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Conserved domains on  [gi|564337089|ref|XP_006232666|]
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large ribosomal subunit protein uL24m isoform X1 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RplX COG0198
Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 ...
 59-154 4.12e-20

Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 is part of the Pathway/BioSystem: Ribosome 50S subunit


:

Pssm-ID: 439968 [Multi-domain]  Cd Length: 104  Bit Score: 81.26  E-value: 4.12e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564337089  59 GDMVEILEGKDAGKQGKVVQVVRQRNWVVLEGLNTHYRYIGRTKDHR-GTMIPSEAPLLHHQVKLVDPVDRKPTEIQWRF 137
Cdd:COG0198    8 GDTVIVIAGKDKGKRGKVLKVLPKKNRVIVEGVNIVKKHQKPNQQNPqGGIIEKEAPIHISNVMLVDPKTGKPTRVGFKV 87

                         90
                 ....*....|....*..
gi 564337089 138 TEAGERVRVSTRSGRII 154
Cdd:COG0198   88 LEDGKKVRVCKKSGEVI 104
 
Name Accession Description Interval E-value
RplX COG0198
Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 ...
 59-154 4.12e-20

Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 439968 [Multi-domain]  Cd Length: 104  Bit Score: 81.26  E-value: 4.12e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564337089  59 GDMVEILEGKDAGKQGKVVQVVRQRNWVVLEGLNTHYRYIGRTKDHR-GTMIPSEAPLLHHQVKLVDPVDRKPTEIQWRF 137
Cdd:COG0198    8 GDTVIVIAGKDKGKRGKVLKVLPKKNRVIVEGVNIVKKHQKPNQQNPqGGIIEKEAPIHISNVMLVDPKTGKPTRVGFKV 87

                         90
                 ....*....|....*..
gi 564337089 138 TEAGERVRVSTRSGRII 154
Cdd:COG0198   88 LEDGKKVRVCKKSGEVI 104
rplX_bact TIGR01079
ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar ...
 59-154 6.80e-19

ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar forms of ribosomal protein L24. It excludes eukaryotic and archaeal forms, designated L26 in eukaryotes. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273431 [Multi-domain]  Cd Length: 102  Bit Score: 78.08  E-value: 6.80e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564337089   59 GDMVEILEGKDAGKQGKVVQVVRQRNWVVLEGLNTHYRYIGRTKDHR-GTMIPSEAPLLHHQVKLVDPVDRKPTEIQWRF 137
Cdd:TIGR01079   6 GDTVKVISGKDKGKRGKVLKVLPKKNKVIVEGVNMVKKHVKPVPANRqGGIIEKEAPIHISNVMLFDPKTGKATRVGYRF 85

                          90
                  ....*....|....*..
gi 564337089  138 TEAGERVRVSTRSGRII 154
Cdd:TIGR01079  86 EEDGKKVRVFKKNGEII 102
KOW_RPL26 cd06089
KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at ...
 59-122 1.53e-18

KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at their N terminal. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. RPL26 makes a very minor contributions to the biogenesis, structure, and function of 60s ribosomal subunits. However, RPL24 is essential to generate the first intermediate during 50s ribosomal subunits assembly. RPL26 have an extra-ribosomal function to enhances p53 translation after DNA damage.


Pssm-ID: 240513  Cd Length: 65  Bit Score: 76.01  E-value: 1.53e-18
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564337089  59 GDMVEILEGKDAGKQGKVVQVVRQRNWVVLEGLNTHYRYIGRTKDHR-GTMIPSEAPLLHHQVKL 122
Cdd:cd06089    1 GDEVQVIRGKDKGKQGKVLKVDRKKNRVIVEGVNVVKKHVKPSQENPqGGIIEVEAPIHISNVML 65
ribosomal_L24 pfam17136
Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ...
 91-151 2.43e-10

Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ribosomal subunit proteins L24. It also carries some mitochondrial 39S L24 proteins.


Pssm-ID: 465359  Cd Length: 60  Bit Score: 54.37  E-value: 2.43e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564337089   91 LNTHYRYIGRTKDHR-GTMIPSEAPLLHHQVKLVDPVDRKPTEIqwRFTEAGERVRVSTRSG 151
Cdd:pfam17136   1 VNMVKKHVKPSQQNPqGGIIEKEAPIHVSNVMLVDPKCGKPTRV--GFKEDGKKVRVSKKTG 60
rplX PRK12281
50S ribosomal protein L24; Reviewed
 59-123 3.80e-08

50S ribosomal protein L24; Reviewed


Pssm-ID: 183399  Cd Length: 76  Bit Score: 48.88  E-value: 3.80e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564337089  59 GDMVEILEGKDAGKQGKVVQVVRQRNWVVLEGLNTHYRYIGRTKDH-RGTMIPSEAPLLHHQVKLV 123
Cdd:PRK12281  10 GDMVKVIAGDDKGKTGKVLAVLPKKNRVIVEGVKIAKKAIKPSQKNpNGGFIEKEMPIHISNVKKV 75
KOW smart00739
KOW (Kyprides, Ouzounis, Woese) motif; Motif in ribosomal proteins, NusG, Spt5p, KIN17 and T54.
 59-79 8.71e-04

KOW (Kyprides, Ouzounis, Woese) motif; Motif in ribosomal proteins, NusG, Spt5p, KIN17 and T54.


Pssm-ID: 128978  Cd Length: 28  Bit Score: 35.77  E-value: 8.71e-04
                           10        20
                   ....*....|....*....|.
gi 564337089    59 GDMVEILEGKDAGKQGKVVQV 79
Cdd:smart00739   5 GDTVRVIAGPFKGKVGKVLEV 25
 
Name Accession Description Interval E-value
RplX COG0198
Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 ...
 59-154 4.12e-20

Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 439968 [Multi-domain]  Cd Length: 104  Bit Score: 81.26  E-value: 4.12e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564337089  59 GDMVEILEGKDAGKQGKVVQVVRQRNWVVLEGLNTHYRYIGRTKDHR-GTMIPSEAPLLHHQVKLVDPVDRKPTEIQWRF 137
Cdd:COG0198    8 GDTVIVIAGKDKGKRGKVLKVLPKKNRVIVEGVNIVKKHQKPNQQNPqGGIIEKEAPIHISNVMLVDPKTGKPTRVGFKV 87

                         90
                 ....*....|....*..
gi 564337089 138 TEAGERVRVSTRSGRII 154
Cdd:COG0198   88 LEDGKKVRVCKKSGEVI 104
rplX_bact TIGR01079
ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar ...
 59-154 6.80e-19

ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar forms of ribosomal protein L24. It excludes eukaryotic and archaeal forms, designated L26 in eukaryotes. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273431 [Multi-domain]  Cd Length: 102  Bit Score: 78.08  E-value: 6.80e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564337089   59 GDMVEILEGKDAGKQGKVVQVVRQRNWVVLEGLNTHYRYIGRTKDHR-GTMIPSEAPLLHHQVKLVDPVDRKPTEIQWRF 137
Cdd:TIGR01079   6 GDTVKVISGKDKGKRGKVLKVLPKKNKVIVEGVNMVKKHVKPVPANRqGGIIEKEAPIHISNVMLFDPKTGKATRVGYRF 85

                          90
                  ....*....|....*..
gi 564337089  138 TEAGERVRVSTRSGRII 154
Cdd:TIGR01079  86 EEDGKKVRVFKKNGEII 102
KOW_RPL26 cd06089
KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at ...
 59-122 1.53e-18

KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at their N terminal. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. RPL26 makes a very minor contributions to the biogenesis, structure, and function of 60s ribosomal subunits. However, RPL24 is essential to generate the first intermediate during 50s ribosomal subunits assembly. RPL26 have an extra-ribosomal function to enhances p53 translation after DNA damage.


Pssm-ID: 240513  Cd Length: 65  Bit Score: 76.01  E-value: 1.53e-18
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564337089  59 GDMVEILEGKDAGKQGKVVQVVRQRNWVVLEGLNTHYRYIGRTKDHR-GTMIPSEAPLLHHQVKL 122
Cdd:cd06089    1 GDEVQVIRGKDKGKQGKVLKVDRKKNRVIVEGVNVVKKHVKPSQENPqGGIIEVEAPIHISNVML 65
ribosomal_L24 pfam17136
Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ...
 91-151 2.43e-10

Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ribosomal subunit proteins L24. It also carries some mitochondrial 39S L24 proteins.


Pssm-ID: 465359  Cd Length: 60  Bit Score: 54.37  E-value: 2.43e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564337089   91 LNTHYRYIGRTKDHR-GTMIPSEAPLLHHQVKLVDPVDRKPTEIqwRFTEAGERVRVSTRSG 151
Cdd:pfam17136   1 VNMVKKHVKPSQQNPqGGIIEKEAPIHVSNVMLVDPKCGKPTRV--GFKEDGKKVRVSKKTG 60
rplX PRK12281
50S ribosomal protein L24; Reviewed
 59-123 3.80e-08

50S ribosomal protein L24; Reviewed


Pssm-ID: 183399  Cd Length: 76  Bit Score: 48.88  E-value: 3.80e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564337089  59 GDMVEILEGKDAGKQGKVVQVVRQRNWVVLEGLNTHYRYIGRTKDH-RGTMIPSEAPLLHHQVKLV 123
Cdd:PRK12281  10 GDMVKVIAGDDKGKTGKVLAVLPKKNRVIVEGVKIAKKAIKPSQKNpNGGFIEKEMPIHISNVKKV 75
KOW pfam00467
KOW motif; This family has been extended to coincide with ref. The KOW (Kyprides, Ouzounis, ...
 59-89 1.50e-06

KOW motif; This family has been extended to coincide with ref. The KOW (Kyprides, Ouzounis, Woese) motif is found in a variety of ribosomal proteins and NusG.


Pssm-ID: 425698 [Multi-domain]  Cd Length: 32  Bit Score: 43.53  E-value: 1.50e-06
                          10        20        30
                  ....*....|....*....|....*....|.
gi 564337089   59 GDMVEILEGKDAGKQGKVVQVVRQRNWVVLE 89
Cdd:pfam00467   2 GDVVRVIAGPFKGKVGKVVEVDDKKNRVLVE 32
KOW smart00739
KOW (Kyprides, Ouzounis, Woese) motif; Motif in ribosomal proteins, NusG, Spt5p, KIN17 and T54.
 59-79 8.71e-04

KOW (Kyprides, Ouzounis, Woese) motif; Motif in ribosomal proteins, NusG, Spt5p, KIN17 and T54.


Pssm-ID: 128978  Cd Length: 28  Bit Score: 35.77  E-value: 8.71e-04
                           10        20
                   ....*....|....*....|.
gi 564337089    59 GDMVEILEGKDAGKQGKVVQV 79
Cdd:smart00739   5 GDTVRVIAGPFKGKVGKVLEV 25
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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