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coq8 ABC1 kinase family ubiquinone biosynthesis ATPase Coq8 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540411, updated on 18-Sep-2024

Summary

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Official Symbol
coq8
Official Full Name
ABC1 kinase family ubiquinone biosynthesis ATPase Coq8
Primary source
PomBase:SPBC2D10.18
Locus tag
SPOM_SPBC2D10.18
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
abc1
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Genomic context

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See coq8 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (3001174..3003276)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene peptidyl-tRNA hydrolase Pth1 Neighboring gene protein mhf1 Neighboring gene SHREC complex intermodule linker subunit Clr1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ribosome biogenesis protein Alb1 Neighboring gene ubiquitin conjugating enzyme Ubc1 Neighboring gene kinesin-6 family microtubule motor protein Klp9

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The abc1-/coq8- respiratory-deficient mutant of Schizosaccharomyces pombe suffers from glutathione underproduction and hyperaccumulates Cd2+. Gazdag Z, et al. Folia Microbiol (Praha), 2011 Jul. PMID 21818608
  2. Pleiotropic phenotypes of fission yeast defective in ubiquinone-10 production. A study from the abc1Sp (coq8Sp) mutant. Saiki R, et al. Biofactors, 2003. PMID 14695938
  3. Cloning by functional complementation, and inactivation, of the Schizosaccharomyces pombe homologue of the Saccharomyces cerevisiae gene ABC1. Bonnefoy N, et al. Mol Gen Genet, 1996 May 23. PMID 8668131
  4. Polypeptone induces dramatic cell lysis in ura4 deletion mutants of fission yeast. Matsuo Y, et al. PLoS One, 2013. PMID 23555823, Free PMC Article
  5. Functional conservation of coenzyme Q biosynthetic genes among yeasts, plants, and humans. Hayashi K, et al. PLoS One, 2014. PMID 24911838, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The abc1-/coq8- respiratory-deficient mutant of Schizosaccharomyces pombe NBp17 hyperaccumulated yellow CdS.
    Title: The abc1-/coq8- respiratory-deficient mutant of Schizosaccharomyces pombe suffers from glutathione underproduction and hyperaccumulates Cd2+.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables kinase activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in ubiquinone biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ubiquinone biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in extrinsic component of mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
  
is_active_in mitochondrion HDA PubMed 
is_active_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
ABC1 kinase family ubiquinone biosynthesis ATPase Coq8

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    3001174..3003276
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022157.3 → NP_596237.1  ABC1 kinase family ubiquinone biosynthesis ATPase Coq8 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596237.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q92338
    Conserved Domains (2) summary
    COG0661
    Location:170 → 610
    AarF; Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family [Coenzyme transport and metabolism, Signal transduction mechanisms]
    cd13970
    Location:261 → 511
    ABC1_ADCK3; Activator of bc1 complex (ABC1) kinases, also called aarF domain containing kinase 3
Nucleotide Protein
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