3024871 49 ESWEYHPDLIMEFYRKRPLQVLGRLINILFPLLRFILGIWWEKLRGKDPTVSRAK--A-------IQLRELLTNLGPTYI 119 Synechocystis sp. P... 15828014 1 -----MSSTNNHQVVKLDRVPLPVEAARIAATYWQITRAAARVATKLAGKGPWQQkvI-------REIPQTFANLGPTYV 68 Mycobacterium leprae 15840050 36 WHTAQMGSTTHREVAKLDRVPLPVEAARVAATGWQVTRTAVRFIGRLPRKGPWQQkvI-------KELPQTFADLGPTYV 108 Mycobacterium tuber... 15842780 3 D---GSVSDIKRGRAARNAKLASIPVGFAGRAALGLGKRLT-GKSKDEVTAELMEkaA-------NQLFTVLGELKGGAM 71 Mycobacterium tuber... 15610333 3 D---GSVSDIKRGRAARNAKLASIPVGFAGRAALGLGKRLT-GKSKDEVTAELMEkaA-------NQLFTVLGELKGGAM 71 Mycobacterium tuber... 19114177 46 KWMKRFVFVGAAGIGVYAWDRVYNAHALTRSIRTVYTASIIAADYKLNFSEKKADkiDalhqrvaQRLFKTIYKNGGLYI 125 fission yeast 19112714 84 ITLMASVALVDFDPVKHAGVSSKRAYRVVLAGFLCFSDYKKVLGSSYASEEERQLalSechlrcaERSLKVFEENGGIYI 163 fission yeast 3023256 170 SPVILSSSKVPSSQWSRLWHYGGLATSLSVGAIGEKMKRMW-GISKDDGALLLNErnV-------EILVNKLTQMRGAAL 241 fission yeast 112996 63 D--TLKSSSVPTSRISRLFHYGSLAAGVGMNAAAKGISEVAKGNSPTWKSLILSDsnI-------DRITNKFSKMRGVAL 133 baker's yeast 3025214 45 AVVLYNFNDTFHDSVKHTALTTKRIAVVTQATTRCFYHYKRALNKSYENKKEREValNkchkmcaLITLHALRSNGGIYI 124 baker's yeast
3024871 120 KVGQALSTRPDLVPPVF----LDELTTLQDQLPSFPNEVAYRFIEEELGAPAEEIYAELSPEPIAAASLGQVYKGKLKT- 194 Synechocystis sp. P... 15828014 69 KFGQIIASSPSAFGESL----AREFRGLLDQVPPADTNEVHKLFVEELGDAPSKLFASFSEEPFASASIAQVHSAILHS- 143 Mycobacterium leprae 15840050 109 KFGQIIASSPGAFGESL----SREFRGLLDRVPPAKTDEVHKLFVEELGDEPARLFASFEEEPFASASIAQVHYATLRS- 183 Mycobacterium tuber... 15842780 72 KVGQALSVMEAAIPDEFgepyREALTKLQKDAPPLPASKVHRVLDGQLGTKWRERFSSFNDTPVASASIGQVHKAIWSD- 150 Mycobacterium tuber... 15610333 72 KVGQALSVMEAAIPDEFgepyREALTKLQKDAPPLPASKVHRVLDGQLGTKWRERFSSFNDTPVASASIGQVHKAIWSD- 150 Mycobacterium tuber... 19114177 126 KMGQIIAMQSNNLPEAY----GKAFQGMFDNAPQVEWEELQDIFKEQYGRPVEEVFASIEKRAAASASIAQVHRAVLPS- 200 fission yeast 19112714 164 KIGQHLSAMGYVIPKEW----TNTMVKLQDRCPSTSLKDIDHLFRVDTGKGLDETFDEFDPIALGVASLAQVHKARLKDs 239 fission yeast 3023256 242 KMGQMLSFQDSKLIDPRv---SQILERVRDGAHSMPEKQLEQVMVKNLGKNWMTHYSEFDRKPMAAASIGQVHRARLASn 318 fission yeast 112996 134 KIGQLLSFQDEKVLPKEl---YEILSRVQNSANHMPQRQLEKVMAKELGANWKTKFSKFDKIPMAAASIGQVHAAELPS- 209 baker's yeast 3025214 125 KLGQHIGAMTYLLPKEW----TDTMIPLQDHCPESTYEEIDELFKEDLGTSIEDMFLEFNKTPIGVASLAQVHVAKLKNs 200 baker's yeast
3024871 195 ---GEAVAVKVQRPDLVRRITLDIYIMRSLSLWARRSVKRLRSDLVAITDELASRVFEEMNYYQEAINGEKFAQLYG--- 268 Synechocystis sp. P... 15828014 144 ---GEHVVVKIQRPGIRRRVAADLQILKRFAQAVELAKLGRRLSAQDVVADFSDNLAEELNFRLEAQSMEAWGSYLHts- 219 Mycobacterium leprae 15840050 184 ---GEEVVVKIQRPGIRRRVAADLQILKRFAQTVELAKLGRRLSAQDVVADFADNLAEELDFRLEAQSMEAWVSHLHas- 259 Mycobacterium tuber... 15842780 151 ---GREVAVKIQYPGADEALRADLKTMQRMVGVLKQLSPG--ADVQGMVDELVERTEMELDYRLEAANQRAFAKAYH--- 222 Mycobacterium tuber... 15610333 151 ---GREVAVKIQYPGADEALRADLKTMQRMVGVLKQLSPG--ADVQGVVDELVERTEMELDYRLEAANQRAFAKAYH--- 222 Mycobacterium tuber... 19114177 201 ---GEKVAVKIQKPDVAKQMSWDLLVYKYMMYVYDKWIFH--IPLYFTVDYVSERLRSEVDFTTEANNSEHAREGVEetd 275 fission yeast 19112714 240 ---DVWVAVKVQHPSVSLNSPLDLSMTRWVFKAIKTFFPD--FKLMWLADEIERSLPQELDFTREAKNSIETKEHFAh-- 312 fission yeast 3023256 319 ---HMEVVVKVQYPGVMSSIDSDLNNLAYLLKASRILPKG--LFLENSLAAARKELKWECDYEREAAFAERFGSLLK--- 390 fission yeast 112996 210 ---GQRVVVKIQYPGVKESIDSDLNSLLMLLTASSLLPKG--LFLDKTIANARTELKWECDYNREARALQKFEALLK--- 281 baker's yeast 3025214 201 dgkGSSVAVKCQHPSLKEFIPLDVMLTRTVFELLDVFFPD--YPLTWLGDELQSSIYVELNFTKEAENAEKTRHYFSkf- 277 baker's yeast
3024871 269 -SLPEIYVPSIYWQYTGRRVLTMEWVEGIKLTNIKAIQA-QGIDATHLVEVGVQCSLRQLLE-HGFFHADPHPGNLLAMA 345 Synechocystis sp. P... 15828014 220 pLGKNIRVPKVHWEFTGERVLTMEQVHGIRIDNADAIRK-SGFDGVELVKALLFSVFEGGLR-HGLFHGDLHAGNLHVDD 297 Mycobacterium leprae 15840050 260 pLGKNIRVPQVHWDFTTERVLTMERVHGIRIDNAAAIRK-AGFDGVELVKALLFSVFEGGLR-HGLFHGDLHAGNLYVDE 337 Mycobacterium tuber... 15842780 223 -DHPRFQVPHVV--ASAPKVVIQEWIEGVPMAEIIRHGTtEQRD--LIGTLLAELTFDAPRR-LGLMHGDAHPGNFMLLP 296 Mycobacterium tuber... 15610333 223 -DHPRFQVPHVV--ASAPKVVIQEWIEGVPMAEIIRHGTtEQRD--LIGTLLAELTFDAPRR-LGLMHGDAHPGNFMLLP 296 Mycobacterium tuber... 19114177 276 yLRDKIYIPKVYKEISGKRVMVTEWADGIPLYDQTALSE-AGMSKKEILTNLFRFLAFQMFH-SKQVHCDPHPGNILVRK 353 fission yeast 19112714 313 -LSTSLYVPEVMWS--KPRILVMEYVAGARIDNLSFMDE-HSISRDLVSVDICHIFNEMIFGkGGHLHCDPHGGNVLIRS 388 fission yeast 3023256 391 -NDSDFKVPMVFREASGPSVITLEYLHGIALGKQ--KYSqATRN--HIGYLLTKQCLREISE-YHFMQTDPNWSNFLYNG 464 fission yeast 112996 282 -DDPAFEVPHVFPEYTTDNIITMTRMEGTEIMKLP-KASqETKN--FISENIMRLCLEEIAT-FKYMQTDPNWANFLYNG 356 baker's yeast 3025214 278 kKQTALKIPKVIES--HKRILIMEYVGGKRLDDLEYIDS-HGISRSEVSSCLSHIFNNMIFTpNVGIHCDPHGGNLAIRS 354 baker's yeast
3024871 346 D----------GRLAYLDFGMMSTIQPYQRYGLIEAVVHLVNR-DFDSLAKDYVKLDFLKP-DTDLKPIIPALGQVFGNA 413 Synechocystis sp. P... 15828014 298 Q----------GRIVFFDFGIMGRIDPRTRWLLRELVFALLVKkDHAAAGKIVVLMGAVGT-VKPEARAAKDLENFTTPL 366 Mycobacterium leprae 15840050 338 A----------GRIVFFDFGIMGRIDPRTRWLLRELVYALLVKkDHAAAGKIVVLMGAVGT-MKPETQAAKDLERFATPL 406 Mycobacterium tuber... 15842780 297 D----------GRMGIIDFGAVAPMPGGFPIELGMTIRLAREK-NYDLLLPTMEKAGLIQ---RGRQVSVREIDEMLR-- 360 Mycobacterium tuber... 15610333 297 D----------GRMGIIDFGAVAPMPGGFPIELGMTIRLAREK-NYDLLLPTMEKAGLIQ---RGRQVSVREIDEMLR-- 360 Mycobacterium tuber... 19114177 354 Nqa------glCQTVILDHGLYVFESEKFRKEFALLFTAAYSL-DKKSILQVMDAWGIGQPeLFANRMLNIPMDEEQPHT 426 fission yeast 19112714 389 Kpknsk-sprnYEIVLLDHGLYRDIPHELQVDYANMWLNIINF-NEKNLKFYAKKVANVSD--ENFPIFATAITGRPYKS 464 fission yeast 3023256 465 Kt---------KKIELLDFGASIEYDEKFIKKYCRLLLAAAHR-NREKCKKLSVELGYLNN-HESAQMIDAHINSIF--- 530 fission yeast 112996 357 Rt---------KKIELLDFGASRPFAEDFILKYRKLLTYATLR-DRKGAYEMSVQLGYLTG-LESQSMKDAHVDSVL--- 422 baker's yeast 3025214 355 VkpakdngyhnFEIVLFDHGLYRYPSTRTRRLYAKFWLSLLFD--KDQTKMKKYAKGFANItDEQFPLLAAAITGRSIDA 432 baker's yeast
3024871 414 -LG--ASVAELNFKSITDQMSAMMYEFPFRVPAYYALIIRSMVTLEGIAIGIDPNFKVLSKAYPYIAKRLLTDQSEElrt 490 Synechocystis sp. P... 15828014 367 -AM--KTLGDMSYTDIGRQLSALSDAYNVKLPRELVLIGKQFLYVERYMKLLAPEWQIML--DPELTGYFANFMVEV--- 438 Mycobacterium leprae 15840050 407 -TM--QSLGDMSYADIGRQLSALADAYDVKLPRELVLIGKQFLYVERYMKLLAPRWQMMS--DPQLTGYFANFMVEV--- 478 Mycobacterium tuber... 15842780 361 -QY--VEPIQVEVFHYTRKWLQKMTVSQIDRSVAQIRTARQMDLPAKLAIPMRVIASVGAILCQLDAHVPIKALSEE--- 434 Mycobacterium tuber... 15610333 361 -QY--VEPIQVEVFHYTRKWLQKMTVSQIDRSVAQIRTARQMDLPAKLAIPMRVIASVGAILCQLDAHVPIKALSEE--- 434 Mycobacterium tuber... 19114177 427 gEKiiSKKEAFQQQLAERKKFIGFLQDCTRLPKELLMLGRCLMLIQKNNQNFGYPVNSIAVMAKVADKYTTDKPSPT--- 503 fission yeast 19112714 465 lKS--LPIGGPNHEEEQKKFISALQKGGMLQSIIRLLSTMPRLTLLLMKTNDLVRSLDENLKTKSGPEKLYLIMARY--- 539 fission yeast 3023256 531 -TL--AEPFAFDAPDVYDFGDQTIT-ARVKQQIPVMLDLRLQPPPEETYSLHRRLSGHFLLCAKLGAKVRCKELFSG--- 603 fission yeast 112996 423 -TL--GEPFRGDVDKSFDFKDQTVS-DRIRGNIGLMLNERLCPPPEETYSLHRKFSGIFLLCARMGASVHCAKLFKE--- 495 baker's yeast 3025214 433 aLN--YDISTSRTQEEMDVMANGILEGTLLSDLMSILSRIPRVVLLILKTNDLTRHLDECLQNPLGPERTFLIMTQY--- 507 baker's yeast
3024871 491 sLKELLFKEGSFRWNRLENLLRNAKNSPGFDFDyvlneATEFLLSDRGQFIRDRLVAELV 550 Synechocystis sp. PCC 6803 15828014 439 --SREHQSDVEI------------------------------------------------ 448 Mycobacterium leprae 15840050 479 --SREHQSDIEV------------------------------------------------ 488 Mycobacterium tuberculosis CDC1551 15842780 435 -LIPGFAEPDAIVV---------------------------------------------- 447 Mycobacterium tuberculosis CDC1551 15610333 435 -LIPGFAEPDAIVV---------------------------------------------- 447 Mycobacterium tuberculosis H37Rv 19114177 504 -WYQRLLSPIFWVFQHLFYPGNFRLPELTNDKK--------------------------- 535 fission yeast 19112714 540 -CLRCVYDDKMDSLWNSRSFWVSKVFKGTYYRLsylfsSLKYTLAENYFYYKHMYL---- 594 fission yeast 3023256 604 -MLKHYAD---------------------------------------------------- 610 fission yeast 112996 496 -IFAYKV----------------------------------------------------- 501 baker's yeast 3025214 508 -CAKTVYDEKVERINSEYARWSIKWMWENLTNWivyerRINQLYFYDFVLWWKKFIPKTW 566 baker's yeast
Jiyao W et al.(2023). "The conserved domain database in 2023.",