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CAMTA1 calmodulin binding transcription activator 1 [ Homo sapiens (human) ]

Gene ID: 23261, updated on 3-Apr-2024

Summary

Official Symbol
CAMTA1provided by HGNC
Official Full Name
calmodulin binding transcription activator 1provided by HGNC
Primary source
HGNC:HGNC:18806
See related
Ensembl:ENSG00000171735 MIM:611501; AllianceGenome:HGNC:18806
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CECBA; CANPMR
Summary
The protein encoded by this gene contains a CG1 DNA-binding domain, a transcription factor immunoglobulin domain, ankyrin repeats, and calmodulin-binding IQ motifs. The encoded protein is thought to be a transcription factor and may be a tumor suppressor. However, a translocation event is sometimes observed between this gene and the WWTR1 gene, with the resulting WWTR1-CAMTA1 oncoprotein leading to epithelioid hemangioendothelioma, a malignant vascular cancer. [provided by RefSeq, Mar 2017]
Expression
Ubiquitous expression in brain (RPKM 5.0), adrenal (RPKM 1.5) and 24 other tissues See more
Orthologs
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Genomic context

Location:
1p36.31-p36.23
Exon count:
42
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (6785454..7769706)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (6313294..7300752)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (6845514..7829766)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U13 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:6843880-6844556 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:6844557-6845231 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 177 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 178 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 179 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:6868944-6869444 Neighboring gene uncharacterized LOC124903832 Neighboring gene CAMTA1 divergent transcript Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:6927405-6928137 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:6967713-6968438 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:6969150-6969650 Neighboring gene ribosomal protein L37 pseudogene 9 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:6969651-6970151 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:6990406-6990906 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7011017-7011720 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7016017-7016546 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr1:7016547-7017077 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr1:7017078-7017607 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 180 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 181 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 182 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7029419-7029919 Neighboring gene MPRA-validated peak33 silencer Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7039565-7040410 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 183 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr1:7086000-7087199 Neighboring gene CAMTA1 antisense RNA 3 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7109791-7110690 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 89 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:7142559-7142729 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:7153467-7153661 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7209665-7210272 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7234210-7234710 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr1:7237955-7238455 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7284388-7284888 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7284889-7285389 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7305529-7306030 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7344591-7345092 Neighboring gene RNA, U1 small nuclear 8, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7354235-7354752 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr1:7377679-7378878 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7395955-7396832 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7433523-7434023 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7438503-7439129 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7439130-7439755 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7439756-7440382 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7440383-7441007 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7448189-7448726 Neighboring gene CAMTA1 intronic transcript 1 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr1:7461491-7462690 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7463312-7463812 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7469057-7469988 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7469989-7470920 Neighboring gene CAMTA1 antisense RNA 2 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:7491149-7491650 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7517439-7518106 Neighboring gene CAMTA1 antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7530650-7531194 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7532917-7533608 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7551761-7552396 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7560506-7561006 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7561007-7561507 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7562099-7562599 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7565577-7566214 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7563935-7564790 Neighboring gene uncharacterized LOC105376691 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7563077-7563934 Neighboring gene MPRA-validated peak35 silencer Neighboring gene MPRA-validated peak36 silencer Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7594027-7595006 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7598278-7598983 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7643497-7643996 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7646449-7647169 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7655704-7656204 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7668502-7669038 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7669039-7669576 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7669577-7670113 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7670114-7670651 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7672975-7673506 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7673507-7674037 Neighboring gene MPRA-validated peak37 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7685250-7685750 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7695174-7696155 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7700515-7701015 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7702117-7703085 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7703871-7704371 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7710763-7711264 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7711265-7711764 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7717029-7717568 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7723269-7723770 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 90 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7729239-7730085 Neighboring gene translation initiation factor IF-2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 185 Neighboring gene MPRA-validated peak40 silencer Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr1:7798026-7799225 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:7830560-7831256 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:7831283-7831525 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 186 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 187 Neighboring gene uncharacterized LOC124903833 Neighboring gene MPRA-validated peak42 silencer Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr1:7886590-7887789 Neighboring gene vesicle associated membrane protein 3 Neighboring gene period circadian regulator 3

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Cerebellar dysfunction with variable cognitive and behavioral abnormalities
MedGen: C3553661 OMIM: 614756 GeneReviews: Not available
Compare labs

Copy number response

Description
Copy number response
Triplosensitivity

No evidence available (Last evaluated 2017-12-14)

ClinGen Genome Curation Page
Haploinsufficency

Sufficient evidence for dosage pathogenicity (Last evaluated 2017-12-14)

ClinGen Genome Curation PagePubMed

EBI GWAS Catalog

Description
Cross-Disorder Genome-Wide Analyses Suggest a Complex Genetic Relationship Between Tourette's Syndrome and OCD.
EBI GWAS Catalog
Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.
EBI GWAS Catalog
Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortiu
EBI GWAS Catalog
Genome-wide association study of periodontal pathogen colonization.
EBI GWAS Catalog
Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • KIAA0833

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables double-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables transcription coregulator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 
located_in nucleolus IDA
Inferred from Direct Assay
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
calmodulin-binding transcription activator 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_053148.1 RefSeqGene

    Range
    5131..989383
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001195563.2NP_001182492.1  calmodulin-binding transcription activator 1 isoform b

    See identical proteins and their annotated locations for NP_001182492.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) uses an alternate, 3' terminal exon compared to variant 1. This results in a much shorter protein (isoform b, also known as 2) that lacks the ankyrin repeats and calmodulin-binding motifs, compared to isoform a.
    Source sequence(s)
    AB020640, BC116457
    Consensus CDS
    CCDS55574.1
    UniProtKB/TrEMBL
    H0YJV1
    Related
    ENSP00000451388.1, ENST00000473578.5
  2. NM_001242701.2NP_001229630.1  calmodulin-binding transcription activator 1 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) uses an alternate, 3' terminal exon compared to variant 1. This results in a shorter protein (isoform c, also known as 3) that lacks the ankyrin repeats and calmodulin-binding motifs, compared to isoform a.
    Source sequence(s)
    AI278074, BC151835, CD103791
    Consensus CDS
    CCDS55575.1
    UniProtKB/Swiss-Prot
    Q9Y6Y1
    Related
    ENSP00000451510.1, ENST00000557126.5
  3. NM_001349608.2NP_001336537.1  calmodulin-binding transcription activator 1 isoform d

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) encodes isoform d.
    Source sequence(s)
    AL359881, AL365194, AL590128, AL596210, KF495855, Z97635, Z98052, Z98884
    Conserved Domains (4) summary
    smart01076
    Location:37153
    CG-1; CG-1 domains are highly conserved domains of about 130 amino-acid residues
    cd00204
    Location:10351156
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:10341077
    ANK; ANK repeat [structural motif]
    pfam01833
    Location:843922
    TIG; IPT/TIG domain
  4. NM_001349609.2NP_001336538.1  calmodulin-binding transcription activator 1 isoform e

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) encodes isoform e.
    Source sequence(s)
    AL359881, AL365194, AL590128, AL596210, KF495855, Z97635, Z98052, Z98884
    Conserved Domains (4) summary
    smart01076
    Location:67183
    CG-1; CG-1 domains are highly conserved domains of about 130 amino-acid residues
    cd00204
    Location:10651186
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:10641107
    ANK; ANK repeat [structural motif]
    pfam01833
    Location:873952
    TIG; IPT/TIG domain
  5. NM_001349610.2NP_001336539.1  calmodulin-binding transcription activator 1 isoform f

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) encodes isoform f.
    Source sequence(s)
    AL359881, AL365194, AL590128, AL596210, KF495855, Z97635, Z98052, Z98884
    Conserved Domains (4) summary
    smart01076
    Location:67183
    CG-1; CG-1 domains are highly conserved domains of about 130 amino-acid residues
    cd00204
    Location:10651186
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:10641107
    ANK; ANK repeat [structural motif]
    pfam01833
    Location:873952
    TIG; IPT/TIG domain
  6. NM_001349612.2NP_001336541.1  calmodulin-binding transcription activator 1 isoform g

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) encodes isoform g.
    Source sequence(s)
    AL359881, AL365194, AL590128, AL596210, KF495855, Z97635, Z98052, Z98884
    Consensus CDS
    CCDS90851.1
    UniProtKB/TrEMBL
    A0A8V8TQ65
    Related
    ENSP00000514979.1, ENST00000700415.1
    Conserved Domains (4) summary
    smart01076
    Location:37153
    CG-1; CG-1 domains are highly conserved domains of about 130 amino-acid residues
    cd00204
    Location:10351156
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:10341077
    ANK; ANK repeat [structural motif]
    pfam01833
    Location:843922
    TIG; IPT/TIG domain
  7. NM_001349613.1NP_001336542.1  calmodulin-binding transcription activator 1 isoform h

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) encodes isoform h.
    Source sequence(s)
    AL359881, KF495855, Z98884
    UniProtKB/TrEMBL
    B4DXR3
    Conserved Domains (2) summary
    cd00204
    Location:108229
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:107150
    ANK; ANK repeat [structural motif]
  8. NM_001349614.1NP_001336543.1  calmodulin-binding transcription activator 1 isoform i

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10), as well as variant 11, encodes isoform i.
    Source sequence(s)
    AL359881, KF495855, Z98884
    UniProtKB/TrEMBL
    A0AA34QVU6
    Conserved Domains (2) summary
    sd00045
    Location:88131
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:93185
    Ank_2; Ankyrin repeats (3 copies)
  9. NM_001349615.2NP_001336544.1  calmodulin-binding transcription activator 1 isoform i

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11), as well as variant 10, encodes isoform i.
    Source sequence(s)
    AL359881, KF495855, Z98884
    UniProtKB/TrEMBL
    A0AA34QVU6
    Related
    ENSP00000518175.1, ENST00000710285.1
    Conserved Domains (2) summary
    sd00045
    Location:88131
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:93185
    Ank_2; Ankyrin repeats (3 copies)
  10. NM_001349616.2NP_001336545.1  calmodulin-binding transcription activator 1 isoform j

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12) encodes isoform j.
    Source sequence(s)
    AL359881, KF495855, Z98884
    UniProtKB/TrEMBL
    A0A8V8TR82
    Conserved Domains (2) summary
    cd00204
    Location:89210
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:88131
    ANK; ANK repeat [structural motif]
  11. NM_001349617.1NP_001336546.1  calmodulin-binding transcription activator 1 isoform k

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13), as well as variant 14, encodes isoform k.
    Source sequence(s)
    AL359881, KF495855, Z98884
    Consensus CDS
    CCDS90852.1
    UniProtKB/TrEMBL
    A0A8V8TPQ2, A0A8V8TR82
    Related
    ENSP00000514995.1, ENST00000700421.1
    Conserved Domains (2) summary
    cd00204
    Location:89210
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:88131
    ANK; ANK repeat [structural motif]
  12. NM_001349618.2NP_001336547.1  calmodulin-binding transcription activator 1 isoform k

    Status: REVIEWED

    Description
    Transcript Variant: This variant (14), as well as variant 13, encodes isoform k.
    Source sequence(s)
    AL359881, KF495855, Z98884
    Consensus CDS
    CCDS90852.1
    UniProtKB/TrEMBL
    A0A8V8TPQ2, A0A8V8TR82
    Conserved Domains (2) summary
    cd00204
    Location:89210
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:88131
    ANK; ANK repeat [structural motif]
  13. NM_001349619.2NP_001336548.1  calmodulin-binding transcription activator 1 isoform l

    Status: REVIEWED

    Description
    Transcript Variant: This variant (15), as well as variant 16, encodes isoform l.
    Source sequence(s)
    AL359881, KF495855, Z98884
    Consensus CDS
    CCDS90853.1
    UniProtKB/TrEMBL
    A0A8V8TQ84, A0A8V8TQA4
    Related
    ENSP00000514996.1, ENST00000700423.1
    Conserved Domains (3) summary
    cd00204
    Location:89210
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:88131
    ANK; ANK repeat [structural motif]
    cl27381
    Location:435561
    Myosin_head; Myosin head (motor domain)
  14. NM_001349620.1NP_001336549.1  calmodulin-binding transcription activator 1 isoform l

    Status: REVIEWED

    Description
    Transcript Variant: This variant (16), as well as variant 15, encodes isoform l.
    Source sequence(s)
    AL359881, KF495855, Z98884
    Consensus CDS
    CCDS90853.1
    UniProtKB/TrEMBL
    A0A8V8TQ84, A0A8V8TQA4
    Conserved Domains (3) summary
    cd00204
    Location:89210
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:88131
    ANK; ANK repeat [structural motif]
    cl27381
    Location:435561
    Myosin_head; Myosin head (motor domain)
  15. NM_001349621.1NP_001336550.1  calmodulin-binding transcription activator 1 isoform m

    Status: REVIEWED

    Description
    Transcript Variant: This variant (17), as well as variant 18, encodes isoform m.
    Source sequence(s)
    AL359881, KF495855, Z98884
    Consensus CDS
    CCDS90854.1
    UniProtKB/TrEMBL
    A0A8V8TQX9, A0AA34QVZ9
    Conserved Domains (2) summary
    cd00204
    Location:89210
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:88131
    ANK; ANK repeat [structural motif]
  16. NM_001349622.2NP_001336551.1  calmodulin-binding transcription activator 1 isoform m

    Status: REVIEWED

    Description
    Transcript Variant: This variant (18), as well as variant 17, encodes isoform m.
    Source sequence(s)
    AL359881, KF495855, Z98884
    Consensus CDS
    CCDS90854.1
    UniProtKB/TrEMBL
    A0A8V8TQX9, A0AA34QVZ9
    Related
    ENSP00000514997.1, ENST00000700424.1
    Conserved Domains (2) summary
    cd00204
    Location:89210
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:88131
    ANK; ANK repeat [structural motif]
  17. NM_001349623.1NP_001336552.1  calmodulin-binding transcription activator 1 isoform n

    Status: REVIEWED

    Description
    Transcript Variant: This variant (19), as well as variant 20, encodes isoform n.
    Source sequence(s)
    AL359881, KF495855, Z98884
    Conserved Domains (2) summary
    cd00204
    Location:89210
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:88131
    ANK; ANK repeat [structural motif]
  18. NM_001349624.3NP_001336553.1  calmodulin-binding transcription activator 1 isoform n

    Status: REVIEWED

    Description
    Transcript Variant: This variant (20), as well as variant 19, encodes isoform n.
    Source sequence(s)
    AL359881, KF495855, Z98884
    Conserved Domains (2) summary
    cd00204
    Location:89210
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:88131
    ANK; ANK repeat [structural motif]
  19. NM_001349625.2NP_001336554.1  calmodulin-binding transcription activator 1 isoform o

    Status: REVIEWED

    Description
    Transcript Variant: This variant (21), as well as variant 22, encodes isoform o.
    Source sequence(s)
    AL359881, KF495855, Z98884
    UniProtKB/TrEMBL
    A0A8V8TQA4
    Conserved Domains (2) summary
    cd00204
    Location:89210
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:88131
    ANK; ANK repeat [structural motif]
  20. NM_001349626.2NP_001336555.1  calmodulin-binding transcription activator 1 isoform o

    Status: REVIEWED

    Description
    Transcript Variant: This variant (22), as well as variant 21, encodes isoform o.
    Source sequence(s)
    AL359881, KF495855, Z98884
    UniProtKB/TrEMBL
    A0A8V8TQA4
    Conserved Domains (2) summary
    cd00204
    Location:89210
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:88131
    ANK; ANK repeat [structural motif]
  21. NM_001349627.2NP_001336556.1  calmodulin-binding transcription activator 1 isoform p

    Status: REVIEWED

    Description
    Transcript Variant: This variant (23) encodes isoform p.
    Source sequence(s)
    AL590128
    Consensus CDS
    CCDS85922.1
    UniProtKB/TrEMBL
    G3V297
    Related
    ENSP00000450530.1, ENST00000467404.6
  22. NM_001410737.1NP_001397666.1  calmodulin-binding transcription activator 1 isoform q

    Status: REVIEWED

    Source sequence(s)
    AL359881, AL365194, AL590128, AL596210, KF495855, Z97635, Z98052, Z98884
    Consensus CDS
    CCDS90849.1
    UniProtKB/TrEMBL
    A0A0C4DGL0
    Related
    ENSP00000452319.2, ENST00000476864.2
  23. NM_001410738.1NP_001397667.1  calmodulin-binding transcription activator 1 isoform r

    Status: REVIEWED

    Source sequence(s)
    AL359881, AL590128, AL596210, KF495855, Z97635, Z98052, Z98884
    Consensus CDS
    CCDS90850.1
    UniProtKB/TrEMBL
    A0A8V8TQ87
    Related
    ENSP00000514981.1, ENST00000700417.1
  24. NM_015215.4NP_056030.1  calmodulin-binding transcription activator 1 isoform a

    See identical proteins and their annotated locations for NP_056030.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a, also known as 1).
    Source sequence(s)
    AL359881, BC151835, KF495855, Z98884
    Consensus CDS
    CCDS30576.1
    UniProtKB/Swiss-Prot
    A7MBM4, G3V3Z7, Q5VUE1, Q6V701, Q8WYI3, Q96S92, Q9Y6Y1
    Related
    ENSP00000306522.6, ENST00000303635.12
    Conserved Domains (5) summary
    smart01076
    Location:67183
    CG-1; CG-1 domains are highly conserved domains of about 130 amino-acid residues
    cd00204
    Location:10651186
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam01833
    Location:873952
    TIG; IPT/TIG domain
    pfam13637
    Location:11121163
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:10641107
    ANK; ANK repeat [structural motif]

RNA

  1. NR_038934.2 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) lacks an alternate exon and uses an alternate, 3' terminal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AI278074, BC151835, BM470492
    Related
    ENST00000476163.5
  2. NR_146202.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AL590128
  3. NR_146203.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AL590128
  4. NR_146204.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AL590128
    Related
    ENST00000490738.5

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    6785454..7769706
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011541084.3XP_011539386.1  calmodulin-binding transcription activator 1 isoform X2

    Conserved Domains (5) summary
    smart01076
    Location:67183
    CG-1; CG-1 domains are highly conserved domains of about 130 amino-acid residues
    cd00204
    Location:10651186
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam01833
    Location:873952
    TIG; IPT/TIG domain
    pfam13637
    Location:11121163
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:10641107
    ANK; ANK repeat [structural motif]
  2. XM_011541083.3XP_011539385.1  calmodulin-binding transcription activator 1 isoform X1

    Conserved Domains (5) summary
    smart01076
    Location:67183
    CG-1; CG-1 domains are highly conserved domains of about 130 amino-acid residues
    cd00204
    Location:10651186
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam01833
    Location:873952
    TIG; IPT/TIG domain
    pfam13637
    Location:11121163
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:10641107
    ANK; ANK repeat [structural motif]
  3. XM_011541086.4XP_011539388.1  calmodulin-binding transcription activator 1 isoform X4

    Conserved Domains (5) summary
    smart01076
    Location:67183
    CG-1; CG-1 domains are highly conserved domains of about 130 amino-acid residues
    cd00204
    Location:10651186
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam01833
    Location:873952
    TIG; IPT/TIG domain
    pfam13637
    Location:11121163
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:10641107
    ANK; ANK repeat [structural motif]
  4. XM_011541090.4XP_011539392.1  calmodulin-binding transcription activator 1 isoform X13

    Conserved Domains (5) summary
    smart01076
    Location:67183
    CG-1; CG-1 domains are highly conserved domains of about 130 amino-acid residues
    cd00204
    Location:10651186
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam01833
    Location:873952
    TIG; IPT/TIG domain
    pfam13637
    Location:11121163
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:10641107
    ANK; ANK repeat [structural motif]
  5. XM_017000778.2XP_016856267.1  calmodulin-binding transcription activator 1 isoform X14

  6. XM_011541087.3XP_011539389.1  calmodulin-binding transcription activator 1 isoform X6

    Conserved Domains (5) summary
    cd00204
    Location:10411162
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam01833
    Location:849928
    TIG; IPT/TIG domain
    pfam13637
    Location:10881139
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:10401083
    ANK; ANK repeat [structural motif]
    cl04295
    Location:67159
    CG-1; CG-1 domain
  7. XM_047415997.1XP_047271953.1  calmodulin-binding transcription activator 1 isoform X9

  8. XM_011541088.3XP_011539390.1  calmodulin-binding transcription activator 1 isoform X8

    Conserved Domains (5) summary
    smart01076
    Location:37153
    CG-1; CG-1 domains are highly conserved domains of about 130 amino-acid residues
    cd00204
    Location:10351156
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam01833
    Location:843922
    TIG; IPT/TIG domain
    pfam13637
    Location:10821133
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:10341077
    ANK; ANK repeat [structural motif]
  9. XM_047415999.1XP_047271955.1  calmodulin-binding transcription activator 1 isoform X10

  10. XM_047416005.1XP_047271961.1  calmodulin-binding transcription activator 1 isoform X11

  11. XM_047416024.1XP_047271980.1  calmodulin-binding transcription activator 1 isoform X15

  12. XM_017000774.3XP_016856263.1  calmodulin-binding transcription activator 1 isoform X5

  13. XM_047415993.1XP_047271949.1  calmodulin-binding transcription activator 1 isoform X7

  14. XM_011541091.3XP_011539393.1  calmodulin-binding transcription activator 1 isoform X16

    Conserved Domains (2) summary
    smart01076
    Location:67183
    CG-1; CG-1 domains are highly conserved domains of about 130 amino-acid residues
    pfam01833
    Location:873952
    TIG; IPT/TIG domain
  15. XM_011541092.4XP_011539394.1  calmodulin-binding transcription activator 1 isoform X17

    Conserved Domains (2) summary
    smart01076
    Location:67183
    CG-1; CG-1 domains are highly conserved domains of about 130 amino-acid residues
    pfam01833
    Location:873952
    TIG; IPT/TIG domain
  16. XM_017000780.3XP_016856269.1  calmodulin-binding transcription activator 1 isoform X22

  17. XM_017000781.2XP_016856270.1  calmodulin-binding transcription activator 1 isoform X23

  18. XM_047415988.1XP_047271944.1  calmodulin-binding transcription activator 1 isoform X3

  19. XM_047416009.1XP_047271965.1  calmodulin-binding transcription activator 1 isoform X12

  20. XM_024454334.1XP_024310102.1  calmodulin-binding transcription activator 1 isoform X21

    UniProtKB/TrEMBL
    A0A8V8TR82
    Related
    ENSP00000514994.1, ENST00000700420.1
    Conserved Domains (2) summary
    cd00204
    Location:89210
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:88131
    ANK; ANK repeat [structural motif]
  21. XM_024454329.2XP_024310097.1  calmodulin-binding transcription activator 1 isoform X18

    UniProtKB/TrEMBL
    A0AA34QVU6
    Conserved Domains (2) summary
    cd00204
    Location:152273
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:151194
    ANK; ANK repeat [structural motif]
  22. XM_024454330.2XP_024310098.1  calmodulin-binding transcription activator 1 isoform X19

    UniProtKB/TrEMBL
    B4DXR3
    Conserved Domains (2) summary
    cd00204
    Location:152273
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:151194
    ANK; ANK repeat [structural motif]
  23. XM_024454332.2XP_024310100.1  calmodulin-binding transcription activator 1 isoform X20

    UniProtKB/TrEMBL
    A0AA34QVU6
    Conserved Domains (2) summary
    sd00045
    Location:88131
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:93185
    Ank_2; Ankyrin repeats (3 copies)
  24. XM_024454331.2XP_024310099.1  calmodulin-binding transcription activator 1 isoform X20

    UniProtKB/TrEMBL
    A0AA34QVU6
    Conserved Domains (2) summary
    sd00045
    Location:88131
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:93185
    Ank_2; Ankyrin repeats (3 copies)
  25. XM_024454333.2XP_024310101.1  calmodulin-binding transcription activator 1 isoform X20

    UniProtKB/TrEMBL
    A0AA34QVU6
    Conserved Domains (2) summary
    sd00045
    Location:88131
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:93185
    Ank_2; Ankyrin repeats (3 copies)

RNA

  1. XR_001737064.2 RNA Sequence

  2. XR_001737062.2 RNA Sequence

  3. XR_007057950.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    6313294..7300752
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054335420.1XP_054191395.1  calmodulin-binding transcription activator 1 isoform X2

  2. XM_054335419.1XP_054191394.1  calmodulin-binding transcription activator 1 isoform X1

  3. XM_054335422.1XP_054191397.1  calmodulin-binding transcription activator 1 isoform X4

  4. XM_054335431.1XP_054191406.1  calmodulin-binding transcription activator 1 isoform X13

  5. XM_054335432.1XP_054191407.1  calmodulin-binding transcription activator 1 isoform X14

  6. XM_054335424.1XP_054191399.1  calmodulin-binding transcription activator 1 isoform X6

  7. XM_054335427.1XP_054191402.1  calmodulin-binding transcription activator 1 isoform X9

  8. XM_054335426.1XP_054191401.1  calmodulin-binding transcription activator 1 isoform X8

  9. XM_054335428.1XP_054191403.1  calmodulin-binding transcription activator 1 isoform X10

  10. XM_054335429.1XP_054191404.1  calmodulin-binding transcription activator 1 isoform X11

  11. XM_054335433.1XP_054191408.1  calmodulin-binding transcription activator 1 isoform X15

  12. XM_054335423.1XP_054191398.1  calmodulin-binding transcription activator 1 isoform X5

  13. XM_054335425.1XP_054191400.1  calmodulin-binding transcription activator 1 isoform X7

  14. XM_054335435.1XP_054191410.1  calmodulin-binding transcription activator 1 isoform X17

  15. XM_054335434.1XP_054191409.1  calmodulin-binding transcription activator 1 isoform X16

  16. XM_054335443.1XP_054191418.1  calmodulin-binding transcription activator 1 isoform X24

  17. XM_054335442.1XP_054191417.1  calmodulin-binding transcription activator 1 isoform X22

  18. XM_054335444.1XP_054191419.1  calmodulin-binding transcription activator 1 isoform X23

  19. XM_054335421.1XP_054191396.1  calmodulin-binding transcription activator 1 isoform X3

  20. XM_054335430.1XP_054191405.1  calmodulin-binding transcription activator 1 isoform X12

  21. XM_054335441.1XP_054191416.1  calmodulin-binding transcription activator 1 isoform X21

  22. XM_054335436.1XP_054191411.1  calmodulin-binding transcription activator 1 isoform X18

  23. XM_054335437.1XP_054191412.1  calmodulin-binding transcription activator 1 isoform X19

  24. XM_054335439.1XP_054191414.1  calmodulin-binding transcription activator 1 isoform X20

  25. XM_054335438.1XP_054191413.1  calmodulin-binding transcription activator 1 isoform X20

  26. XM_054335440.1XP_054191415.1  calmodulin-binding transcription activator 1 isoform X20

RNA

  1. XR_008485965.1 RNA Sequence

  2. XR_008485966.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001349628.1: Suppressed sequence

    Description
    NM_001349628.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.