2UZX,3N50


Conserved Protein Domain Family
TIG
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pfam01833: TIG (this model, PSSM-Id:307788 is obsolete and has been replaced by 460355)
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IPT/TIG domain
This family consists of a domain that has an immunoglobulin like fold. These domains are found in cell surface receptors such as Met and Ron as well as in intracellular transcription factors where it is involved in DNA binding. CAUTION: This family does not currently recognize a significant number of members.
Links
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Statistics
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PSSM-Id: 307788
Aligned: 88 rows
Threshold Bit Score: 31.2863
Created: 17-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2UZX_B        542 PAIYKVFP---NSAPLe-gGTRLTICGWDFg--FRRNNkfdlkkTRVLLGNESCTLTl---------SeSTMNTL----- 601  human
B0S5N4       1044 PNISTIEP---NWSIIn-gSTSLTVTGTNLl-tIQEPK------VRAKYGGVETTNIc--------sL-VNDSVM----- 1098 zebrafish
Q5RGW1        163 PEILSLEP---HKVSFn-gRNNVLLRGRNL-----DSV------TKIRIQGDLGCIAkesp---vfdP-SSDTLV----- 218  zebrafish
O45657        750 PRIDKFEP---TSGPIe-gGTIIKIYGNDLgmsVEDVR------GKIYVAGSRCNIVe---------Y-HVSNMI----- 804  Caenorhabditi...
O75051        858 PQITEILT---VSGPPe-gGTRVTIHGVNLgldFSEIA------HHVQVAGVPCTPLpg-------eY-IIAEQI----- 914  human
A0D5V3       1522 LIISASQPtsnNPIVSyagGATITFTGTGFd--TQTEF------SSVQVCGFNCPIT----------S-SSYTSLsceap 1582 Paramecium te...
Q80ZA4       1998 LSIQNIYP---TQGSFg-gGQTLTVTGMGF----DPWN------STILVCNSECAVDk--------lR-SNSTTL----- 2049 house mouse
O45657        928 PSISSIFP---MTSFKa-gGRIVYVQGNSL---NTVQT------AKLFLISSPTPPFyiisdlapchI-INSTLM----- 988  Caenorhabditi...
XP_001626353 1241 MVISDFV----KSESGyggGKIVTIKGSGL-----DSD------TVTKVCGSVCKTV----------S-SAPGQV----- 1289 starlet sea a...
CAA09100      748 PVITLVEP---QCSLHs--GSRLVIQGQNL---DSAHK------TVVEYVSKDANLRplqq--vcngS-TNATHM----- 805  torafugu

2UZX_B        602 ------------KCTVGPAM------------NK-HFNMSIIISNgh---gtTQYSTFSY 633  human
B0S5N4       1099 ------------TCLAPGIIytkreapesgvhPD-EFGFILDHVSal---liLNGTPFTY 1142 zebrafish
Q5RGW1        219 ------------FNIPPSES------------KG-TVKMCVVTPDnr----cHGNSIITY 249  zebrafish
O45657        805 ------------ACQVDKGVs-----------SG-PIRISVGRATva---vaESSELYSF 837  Caenorhabditis elegans
O75051        915 ------------VCEMGHALvg--------ttSG-PVRLCIGECKpef--mtKSHQQYTF 951  human
A0D5V3       1583 kllttsvlqqytALQEPPRY------------IK-LSEVQLLADTiplaqtfFDLQQSTY 1629 Paramecium tetraurelia
Q80ZA4       2050 ------------FCVIPPNNgk--------ghDQ-VCGVSVVNGKds----sHSTKLFTY 2084 house mouse
O45657        989 ------------TCMTPKIL------------ETiTRRVEYTRQPmg---iyPNPTLSPF 1021 Caenorhabditis elegans
XP_001626353 1290 ------------QCEIPAYT------------GSaDTLCPIKCISpdg--rwVMAGFHTY 1323 starlet sea anemone
CAA09100      806 ------------ECWAPALPeem------pdeKE-TGQIYIHMEEql----kVWSSRFEY 842  torafugu
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