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MYT1L myelin transcription factor 1 like [ Homo sapiens (human) ]

Gene ID: 23040, updated on 11-Apr-2024

Summary

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Official Symbol
MYT1Lprovided by HGNC
Official Full Name
myelin transcription factor 1 likeprovided by HGNC
Primary source
HGNC:HGNC:7623
See related
Ensembl:ENSG00000186487 MIM:613084; AllianceGenome:HGNC:7623
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NZF1; MRD39; myT1-L; ZC2H2C2; ZC2HC4B
Summary
This gene encodes a member of the zinc finger superfamily of transcription factors whose expression, thus far, has been found only in neuronal tissues. The encoded protein belongs to a novel class of cystein-cystein-histidine-cystein zinc finger proteins that function in the developing mammalian central nervous system. Forced expression of this gene in combination with the basic helix-loop-helix transcription factor NeuroD1 and the transcription factors POU class 3 homeobox 2 and achaete-scute family basic helix-loop-helix transcription factor 1 can convert fetal and postnatal human fibroblasts into induced neuronal cells, which are able to generate action potentials. Mutations in this gene have been associated with an autosomal dominant form of cognitive disability and with autism spectrum disorder. Alternative splicing results in multiple variants. [provided by RefSeq, Jul 2017]
Expression
Biased expression in brain (RPKM 9.8) and testis (RPKM 1.0) See more
Orthologs
mouse all
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Genomic context

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See MYT1L in Genome Data Viewer
Location:
2p25.3
Exon count:
34
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (1789113..2331275, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (1796915..2341550, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (1792885..2335047, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124907723 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1640917-1641511 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1643345-1644278 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1661268-1661929 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1681235-1682160 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1690124-1690637 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1690638-1691152 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1696267-1696766 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1698687-1699427 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1708299-1708902 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1708903-1709506 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1711357-1712002 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1712003-1712647 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1713293-1713937 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1714484-1714990 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1714991-1715497 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1716916-1717895 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1731880-1732562 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1732563-1733245 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr2:1734173-1734778 Neighboring gene peroxidasin Neighboring gene uncharacterized LOC124907724 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1755052-1755552 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1784798-1785298 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1785299-1785799 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:1805517-1806018 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:1806019-1806518 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1807745-1808377 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1820106-1821018 Neighboring gene uncharacterized LOC124905967 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1829865-1830422 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1842467-1842968 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1845570-1846224 Neighboring gene uncharacterized LOC107985838 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1846879-1847533 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1847534-1848187 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1868997-1869620 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1878441-1878941 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1969195-1969716 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1977845-1978345 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr2:1990006-1990664 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr2:1990665-1991322 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:2010989-2011490 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:2011491-2011992 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:2028319-2028820 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:2028821-2029320 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:2029757-2030573 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11104 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:2149801-2150324 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr2:2150847-2151369 Neighboring gene NANOG hESC enhancer GRCh37_chr2:2252484-2253019 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:2276633-2277264 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:2295761-2296549 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr2:2297557-2298056 Neighboring gene MYT1L antisense RNA 1 Neighboring gene uncharacterized LOC105373389 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11105 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:2530602-2531801 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:2569029-2569986 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:2641129-2641629 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:2650988-2651602 Neighboring gene uncharacterized LOC107985839 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:2660703-2661676 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:2665611-2666112

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. MYT1L-associated neurodevelopmental disorder: description of 40 new cases and literature review of clinical and molecular aspects. Coursimault J, et al. Hum Genet, 2022 Jan. PMID 34748075
  2. A web-based survey on various symptoms of computer vision syndrome and the genetic understanding based on a multi-trait genome-wide association study. Yoshimura K, et al. Sci Rep, 2021 May 3. PMID 33941792, Free PMC Article
  3. MYT1L: A systematic review of genetic variation encompassing schizophrenia and autism. Mansfield P, et al. Am J Med Genet B Neuropsychiatr Genet, 2020 Jun. PMID 32267091, Free PMC Article
  4. Nine newly identified individuals refine the phenotype associated with MYT1L mutations. Windheuser IC, et al. Am J Med Genet A, 2020 May. PMID 32065501
  5. A novel MYT1L mutation in a patient with severe early-onset obesity and intellectual disability. Loid P, et al. Am J Med Genet A, 2018 Sep. PMID 30055078

See all (45) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention.
    Title: MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention.
  2. 2p25.3 microduplications involving MYT1L: further phenotypic characterization through an assessment of 16 new cases and a literature review.
    Title: 2p25.3 microduplications involving MYT1L: further phenotypic characterization through an assessment of 16 new cases and a literature review.
  3. Co-Occurrence of Fragile X Syndrome with a Second Genetic Condition: Three Independent Cases of Double Diagnosis.
    Title: Co-Occurrence of Fragile X Syndrome with a Second Genetic Condition: Three Independent Cases of Double Diagnosis.
  4. MYT1L-associated neurodevelopmental disorder: description of 40 new cases and literature review of clinical and molecular aspects.
    Title: MYT1L-associated neurodevelopmental disorder: description of 40 new cases and literature review of clinical and molecular aspects.
  5. A web-based survey on various symptoms of computer vision syndrome and the genetic understanding based on a multi-trait genome-wide association study.
    Title: A web-based survey on various symptoms of computer vision syndrome and the genetic understanding based on a multi-trait genome-wide association study.
  6. The neuronal transcription factor Myt1L interacts via a conserved motif with the PAH1 domain of Sin3 to recruit the Sin3L/Rpd3L histone deacetylase complex.
    Title: The neuronal transcription factor Myt1L interacts via a conserved motif with the PAH1 domain of Sin3 to recruit the Sin3L/Rpd3L histone deacetylase complex.
  7. Nine newly identified individuals refine the phenotype associated with MYT1L mutations.
    Title: Nine newly identified individuals refine the phenotype associated with MYT1L mutations.
  8. MYT1L: A systematic review of genetic variation encompassing schizophrenia and autism.
    Title: MYT1L: A systematic review of genetic variation encompassing schizophrenia and autism.
  9. The crucial role of DNA-dependent protein kinase and myelin transcription factor 1-like protein in the miR-141 tumor suppressor network.
    Title: The crucial role of DNA-dependent protein kinase and myelin transcription factor 1-like protein in the miR-141 tumor suppressor network.
  10. Our finding supports the association of MYT1L mutations with early-onset syndromic obesity. The identification of novel monogenic forms of childhood-onset obesity will provide insights to the involved genetic and biologic pathways.
    Title: A novel MYT1L mutation in a patient with severe early-onset obesity and intellectual disability.
Submit: New GeneRIF Correction See all GeneRIFs (28)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Intellectual disability, autosomal dominant 39
MedGen: C4225296 OMIM: 616521 GeneReviews: Not available
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Copy number response

Description
Copy number response
Triplosensitivity

No evidence available (Last evaluated 2017-03-09)

ClinGen Genome Curation Page
Haploinsufficency

Sufficient evidence for dosage pathogenicity (Last evaluated 2017-03-09)

ClinGen Genome Curation PagePubMed

EBI GWAS Catalog

Description
Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial.
EBI GWAS Catalog
Genome-wide meta-analysis for severe diabetic retinopathy.
EBI GWAS Catalog
Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific ISA
Inferred from Sequence Alignment
more info
  
enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISS
Inferred from Sequence or Structural Similarity
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in nervous system development ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in neuron development ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in neuron differentiation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in neuron fate commitment ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in neuron fate specification ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
part_of chromatin ISA
Inferred from Sequence Alignment
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
myelin transcription factor 1-like protein
Names
neural zinc finger transcription factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_051313.1 RefSeqGene

    Range
    5114..547276
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001303052.2 → NP_001289981.1  myelin transcription factor 1-like protein isoform 1

    See identical proteins and their annotated locations for NP_001289981.1

    Status: REVIEWED

    Source sequence(s)
    AC011301, AF036943, BC042833, BC137272, BC150281, DA248951
    Consensus CDS
    CCDS77378.1
    UniProtKB/Swiss-Prot
    A7E2C7, B2RP54, Q6IQ17, Q9UL68, Q9UPP6
    UniProtKB/TrEMBL
    A0A3B3ITJ8
    Related
    ENSP00000497479.2, ENST00000647738.2
    Conserved Domains (3) summary
    COG1196
    Location:1033 → 1185
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:904 → 932
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:621 → 872
    MYT1; Myelin transcription factor 1

  2. NM_001329844.2 → NP_001316773.1  myelin transcription factor 1-like protein isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC008276, AC009232, AC009471, AC011301, AC093390, BC042833
    Consensus CDS
    CCDS77378.1
    UniProtKB/Swiss-Prot
    A7E2C7, B2RP54, Q6IQ17, Q9UL68, Q9UPP6
    UniProtKB/TrEMBL
    A0A3B3ITJ8
    Related
    ENSP00000396103.3, ENST00000428368.7
    Conserved Domains (3) summary
    COG1196
    Location:1033 → 1185
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:904 → 932
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:621 → 872
    MYT1; Myelin transcription factor 1

  3. NM_001329845.1 → NP_001316774.1  myelin transcription factor 1-like protein isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC008276, AC009232, AC009471, AC011301, AC093390, BC042833
    Consensus CDS
    CCDS77378.1
    UniProtKB/Swiss-Prot
    A7E2C7, B2RP54, Q6IQ17, Q9UL68, Q9UPP6
    UniProtKB/TrEMBL
    A0A3B3ITJ8
    Related
    ENSP00000497722.1, ENST00000647694.1
    Conserved Domains (3) summary
    COG1196
    Location:1033 → 1185
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:904 → 932
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:621 → 872
    MYT1; Myelin transcription factor 1

  4. NM_001329846.3 → NP_001316775.1  myelin transcription factor 1-like protein isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC008276, AC009232, AC009471, AC011301, AC093390
    Consensus CDS
    CCDS92709.1
    UniProtKB/TrEMBL
    A0A3B3IRT9, A0A3B3IRX5
    Related
    ENSP00000496922.1, ENST00000647755.1
    Conserved Domains (3) summary
    pfam01530
    Location:902 → 930
    zf-C2HC; Zinc finger, C2HC type
    pfam05667
    Location:890 → 1115
    DUF812; Protein of unknown function (DUF812)
    pfam08474
    Location:619 → 870
    MYT1; Myelin transcription factor 1

  5. NM_001329847.2 → NP_001316776.1  myelin transcription factor 1-like protein isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC008276, AC009232, AC009471, AC011301, AC093390, BC042833
    Consensus CDS
    CCDS46222.1
    UniProtKB/TrEMBL
    A0A3B3ITJ8
    Related
    ENSP00000497017.1, ENST00000648928.1
    Conserved Domains (3) summary
    COG1196
    Location:1031 → 1183
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:902 → 930
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:619 → 870
    MYT1; Myelin transcription factor 1

  6. NM_001329848.1 → NP_001316777.1  myelin transcription factor 1-like protein isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC008276, AC009232, AC009471, AC011301, AC093390, BC042833
    Consensus CDS
    CCDS46222.1
    UniProtKB/TrEMBL
    A0A3B3ITJ8
    Related
    ENSP00000496986.1, ENST00000649207.1
    Conserved Domains (3) summary
    COG1196
    Location:1031 → 1183
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:902 → 930
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:619 → 870
    MYT1; Myelin transcription factor 1

  7. NM_001329849.3 → NP_001316778.1  myelin transcription factor 1-like protein isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC008276, AC009232, AC009471, AC011301, AC093390, BC042833
    Consensus CDS
    CCDS92707.1
    UniProtKB/TrEMBL
    A0A3B3IRT9, A0A3B3IS61
    Related
    ENSP00000497115.1, ENST00000648665.2
    Conserved Domains (3) summary
    TIGR04211
    Location:1058 → 1136
    SH3_and_anchor; SH3 domain protein
    pfam01530
    Location:902 → 930
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:619 → 870
    MYT1; Myelin transcription factor 1

  8. NM_001329851.3 → NP_001316780.1  myelin transcription factor 1-like protein isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC008276, AC009232, AC009471, AC011301, AC093390, BC042833
    Consensus CDS
    CCDS92704.1
    UniProtKB/TrEMBL
    A0A3B3IRT9, A0A3B3ISW5
    Related
    ENSP00000497273.1, ENST00000649663.1
    Conserved Domains (1) summary
    COG1196
    Location:1059 → 1126
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  9. NM_001329852.3 → NP_001316781.1  myelin transcription factor 1-like protein isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC008276, AC009232, AC009471, AC011301, AC093390, BC042833
    Consensus CDS
    CCDS92706.1
    UniProtKB/TrEMBL
    A0A3B3IRM3, A0A3B3IRT9
    Related
    ENSP00000496831.1, ENST00000648318.1

  10. NM_015025.4 → NP_055840.2  myelin transcription factor 1-like protein isoform 2

    See identical proteins and their annotated locations for NP_055840.2

    Status: REVIEWED

    Source sequence(s)
    AC011301, BC042833, BC137272, BC150281, DA248951
    Consensus CDS
    CCDS46222.1
    UniProtKB/TrEMBL
    A0A3B3ITJ8
    Related
    ENSP00000382114.3, ENST00000399161.8
    Conserved Domains (3) summary
    COG1196
    Location:1031 → 1183
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:902 → 930
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:619 → 870
    MYT1; Myelin transcription factor 1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    1789113..2331275 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011510326.2 → XP_011508628.1  myelin transcription factor 1-like protein isoform X5

    UniProtKB/TrEMBL
    A0A3B3ITJ8
    Conserved Domains (3) summary
    TIGR04211
    Location:1060 → 1138
    SH3_and_anchor; SH3 domain protein
    pfam01530
    Location:904 → 932
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:621 → 872
    MYT1; Myelin transcription factor 1

  2. XM_011510324.3 → XP_011508626.1  myelin transcription factor 1-like protein isoform X2

    UniProtKB/TrEMBL
    A0A2R8YF72, A0A3B3ITJ8
    Related
    ENSP00000496210.1, ENST00000644820.1
    Conserved Domains (3) summary
    pfam01530
    Location:925 → 951
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:621 → 872
    MYT1; Myelin transcription factor 1
    pfam10267
    Location:1077 → 1149
    Tmemb_cc2; Predicted transmembrane and coiled-coil 2 protein

  3. XM_011510318.2 → XP_011508620.1  myelin transcription factor 1-like protein isoform X1

    See identical proteins and their annotated locations for XP_011508620.1

    UniProtKB/TrEMBL
    A0A3B3ITJ8
    Conserved Domains (3) summary
    pfam01530
    Location:925 → 951
    zf-C2HC; Zinc finger, C2HC type
    pfam05087
    Location:1075 → 1141
    Rota_VP2; Rotavirus VP2 protein
    pfam08474
    Location:621 → 872
    MYT1; Myelin transcription factor 1

  4. XM_017003604.2 → XP_016859093.1  myelin transcription factor 1-like protein isoform X1

    UniProtKB/TrEMBL
    A0A3B3ITJ8
    Conserved Domains (3) summary
    pfam01530
    Location:925 → 951
    zf-C2HC; Zinc finger, C2HC type
    pfam05087
    Location:1075 → 1141
    Rota_VP2; Rotavirus VP2 protein
    pfam08474
    Location:621 → 872
    MYT1; Myelin transcription factor 1

  5. XM_017003612.2 → XP_016859101.1  myelin transcription factor 1-like protein isoform X6

    UniProtKB/TrEMBL
    A0A3B3IS14, A0A3B3ITJ8
    Related
    ENSP00000497068.1, ENST00000650485.2
    Conserved Domains (3) summary
    TIGR04211
    Location:1058 → 1136
    SH3_and_anchor; SH3 domain protein
    pfam01530
    Location:902 → 930
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:619 → 870
    MYT1; Myelin transcription factor 1

  6. XM_017003606.2 → XP_016859095.1  myelin transcription factor 1-like protein isoform X3

    UniProtKB/TrEMBL
    A0A3B3ITJ8
    Conserved Domains (3) summary
    pfam01530
    Location:923 → 949
    zf-C2HC; Zinc finger, C2HC type
    pfam05087
    Location:1073 → 1139
    Rota_VP2; Rotavirus VP2 protein
    pfam08474
    Location:619 → 870
    MYT1; Myelin transcription factor 1

  7. XM_011510319.2 → XP_011508621.1  myelin transcription factor 1-like protein isoform X1

    See identical proteins and their annotated locations for XP_011508621.1

    UniProtKB/TrEMBL
    A0A3B3ITJ8
    Conserved Domains (3) summary
    pfam01530
    Location:925 → 951
    zf-C2HC; Zinc finger, C2HC type
    pfam05087
    Location:1075 → 1141
    Rota_VP2; Rotavirus VP2 protein
    pfam08474
    Location:621 → 872
    MYT1; Myelin transcription factor 1

  8. XM_017003605.2 → XP_016859094.1  myelin transcription factor 1-like protein isoform X1

    UniProtKB/TrEMBL
    A0A3B3ITJ8
    Conserved Domains (3) summary
    pfam01530
    Location:925 → 951
    zf-C2HC; Zinc finger, C2HC type
    pfam05087
    Location:1075 → 1141
    Rota_VP2; Rotavirus VP2 protein
    pfam08474
    Location:621 → 872
    MYT1; Myelin transcription factor 1

  9. XM_011510322.3 → XP_011508624.1  myelin transcription factor 1-like protein isoform X1

    See identical proteins and their annotated locations for XP_011508624.1

    UniProtKB/TrEMBL
    A0A3B3ITJ8
    Conserved Domains (3) summary
    pfam01530
    Location:925 → 951
    zf-C2HC; Zinc finger, C2HC type
    pfam05087
    Location:1075 → 1141
    Rota_VP2; Rotavirus VP2 protein
    pfam08474
    Location:621 → 872
    MYT1; Myelin transcription factor 1

  10. XM_017003607.3 → XP_016859096.1  myelin transcription factor 1-like protein isoform X3

    UniProtKB/TrEMBL
    A0A3B3ITJ8
    Conserved Domains (3) summary
    pfam01530
    Location:923 → 949
    zf-C2HC; Zinc finger, C2HC type
    pfam05087
    Location:1073 → 1139
    Rota_VP2; Rotavirus VP2 protein
    pfam08474
    Location:619 → 870
    MYT1; Myelin transcription factor 1

  11. XM_011510320.4 → XP_011508622.1  myelin transcription factor 1-like protein isoform X1

    See identical proteins and their annotated locations for XP_011508622.1

    UniProtKB/TrEMBL
    A0A3B3ITJ8
    Conserved Domains (3) summary
    pfam01530
    Location:925 → 951
    zf-C2HC; Zinc finger, C2HC type
    pfam05087
    Location:1075 → 1141
    Rota_VP2; Rotavirus VP2 protein
    pfam08474
    Location:621 → 872
    MYT1; Myelin transcription factor 1

  12. XM_011510321.3 → XP_011508623.1  myelin transcription factor 1-like protein isoform X1

    See identical proteins and their annotated locations for XP_011508623.1

    UniProtKB/TrEMBL
    A0A3B3ITJ8
    Conserved Domains (3) summary
    pfam01530
    Location:925 → 951
    zf-C2HC; Zinc finger, C2HC type
    pfam05087
    Location:1075 → 1141
    Rota_VP2; Rotavirus VP2 protein
    pfam08474
    Location:621 → 872
    MYT1; Myelin transcription factor 1

  13. XM_011510323.1 → XP_011508625.1  myelin transcription factor 1-like protein isoform X1

    See identical proteins and their annotated locations for XP_011508625.1

    UniProtKB/TrEMBL
    A0A3B3ITJ8
    Conserved Domains (3) summary
    pfam01530
    Location:925 → 951
    zf-C2HC; Zinc finger, C2HC type
    pfam05087
    Location:1075 → 1141
    Rota_VP2; Rotavirus VP2 protein
    pfam08474
    Location:621 → 872
    MYT1; Myelin transcription factor 1

  14. XM_017003620.1 → XP_016859109.1  myelin transcription factor 1-like protein isoform X11

    UniProtKB/TrEMBL
    A0A3B3IS77
    Related
    ENSP00000497206.2, ENST00000648753.2
    Conserved Domains (3) summary
    pfam01530
    Location:827 → 853
    zf-C2HC; Zinc finger, C2HC type
    pfam05087
    Location:977 → 1043
    Rota_VP2; Rotavirus VP2 protein
    pfam08474
    Location:523 → 774
    MYT1; Myelin transcription factor 1

  15. XM_017003616.2 → XP_016859105.1  myelin transcription factor 1-like protein isoform X10

    UniProtKB/TrEMBL
    A0A3B3IRT9
    Conserved Domains (3) summary
    pfam01530
    Location:904 → 932
    zf-C2HC; Zinc finger, C2HC type
    pfam05667
    Location:892 → 1117
    DUF812; Protein of unknown function (DUF812)
    pfam08474
    Location:621 → 872
    MYT1; Myelin transcription factor 1

  16. XM_017003615.2 → XP_016859104.1  myelin transcription factor 1-like protein isoform X9

    UniProtKB/TrEMBL
    A0A3B3IRT9
    Conserved Domains (3) summary
    TIGR04211
    Location:1060 → 1138
    SH3_and_anchor; SH3 domain protein
    pfam01530
    Location:904 → 932
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:621 → 872
    MYT1; Myelin transcription factor 1

  17. XM_011510328.3 → XP_011508630.1  myelin transcription factor 1-like protein isoform X8

    UniProtKB/TrEMBL
    A0A3B3IRT9
    Conserved Domains (3) summary
    pfam01530
    Location:925 → 951
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:621 → 872
    MYT1; Myelin transcription factor 1
    pfam10267
    Location:1077 → 1149
    Tmemb_cc2; Predicted transmembrane and coiled-coil 2 protein

  18. XM_011510327.2 → XP_011508629.1  myelin transcription factor 1-like protein isoform X7

    UniProtKB/TrEMBL
    A0A3B3IRT9
    Conserved Domains (3) summary
    pfam01530
    Location:925 → 951
    zf-C2HC; Zinc finger, C2HC type
    pfam05087
    Location:1075 → 1141
    Rota_VP2; Rotavirus VP2 protein
    pfam08474
    Location:621 → 872
    MYT1; Myelin transcription factor 1

  19. XM_017003608.2 → XP_016859097.1  myelin transcription factor 1-like protein isoform X4

    UniProtKB/TrEMBL
    A0A3B3IRT9

  20. XM_011510332.3 → XP_011508634.1  myelin transcription factor 1-like protein isoform X14

    UniProtKB/TrEMBL
    B4DS48
    Conserved Domains (2) summary
    pfam01530
    Location:30 → 56
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:621 → 872
    MYT1; Myelin transcription factor 1

  21. XM_017003622.2 → XP_016859111.1  myelin transcription factor 1-like protein isoform X15

    UniProtKB/TrEMBL
    B4DS48
    Related
    ENSP00000498096.1, ENST00000649810.1

  22. XM_011510331.3 → XP_011508633.1  myelin transcription factor 1-like protein isoform X12

    UniProtKB/TrEMBL
    B4DS48
    Conserved Domains (2) summary
    pfam01530
    Location:882 → 907
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:621 → 872
    MYT1; Myelin transcription factor 1

  23. XM_017003621.2 → XP_016859110.1  myelin transcription factor 1-like protein isoform X13

    UniProtKB/TrEMBL
    B4DS48

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    1796915..2341550 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054341060.1 → XP_054197035.1  myelin transcription factor 1-like protein isoform X6

    UniProtKB/TrEMBL
    A0A3B3IS14

  2. XM_054341057.1 → XP_054197032.1  myelin transcription factor 1-like protein isoform X3

  3. XM_054341059.1 → XP_054197034.1  myelin transcription factor 1-like protein isoform X5

  4. XM_054341056.1 → XP_054197031.1  myelin transcription factor 1-like protein isoform X2

    UniProtKB/TrEMBL
    A0A2R8YF72

  5. XM_054341048.1 → XP_054197023.1  myelin transcription factor 1-like protein isoform X1

  6. XM_054341054.1 → XP_054197029.1  myelin transcription factor 1-like protein isoform X1

  7. XM_054341049.1 → XP_054197024.1  myelin transcription factor 1-like protein isoform X1

  8. XM_054341053.1 → XP_054197028.1  myelin transcription factor 1-like protein isoform X1

  9. XM_054341052.1 → XP_054197027.1  myelin transcription factor 1-like protein isoform X1

  10. XM_054341050.1 → XP_054197025.1  myelin transcription factor 1-like protein isoform X1

  11. XM_054341051.1 → XP_054197026.1  myelin transcription factor 1-like protein isoform X1

  12. XM_054341055.1 → XP_054197030.1  myelin transcription factor 1-like protein isoform X1

  13. XM_054341066.1 → XP_054197041.1  myelin transcription factor 1-like protein isoform X11

  14. XM_054341065.1 → XP_054197040.1  myelin transcription factor 1-like protein isoform X16

    UniProtKB/TrEMBL
    A0A3B3IRX5

  15. XM_054341064.1 → XP_054197039.1  myelin transcription factor 1-like protein isoform X10

  16. XM_054341063.1 → XP_054197038.1  myelin transcription factor 1-like protein isoform X9

  17. XM_054341062.1 → XP_054197037.1  myelin transcription factor 1-like protein isoform X8

  18. XM_054341061.1 → XP_054197036.1  myelin transcription factor 1-like protein isoform X7

  19. XM_054341058.1 → XP_054197033.1  myelin transcription factor 1-like protein isoform X4

  20. XM_054341069.1 → XP_054197044.1  myelin transcription factor 1-like protein isoform X14

  21. XM_054341070.1 → XP_054197045.1  myelin transcription factor 1-like protein isoform X15

  22. XM_054341067.1 → XP_054197042.1  myelin transcription factor 1-like protein isoform X12

  23. XM_054341068.1 → XP_054197043.1  myelin transcription factor 1-like protein isoform X13

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9UL68.3 GenPept UniProtKB/Swiss-Prot:Q9UL68

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