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Conserved domains on  [gi|767913177|ref|XP_011508634|]
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myelin transcription factor 1-like protein isoform X14 [Homo sapiens]

Protein Classification

zf-C2HC and MYT1 domain-containing protein( domain architecture ID 10479203)

zf-C2HC and MYT1 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MYT1 pfam08474
Myelin transcription factor 1; This domain is found in the myelin transcription factor 1 (MYT1) ...
 621-872 6.79e-123

Myelin transcription factor 1; This domain is found in the myelin transcription factor 1 (MYT1) of chordates. MYT1 contains C2HC zinc finger domains (pfam01530) and is expressed in developing neurons of the central nervous system where it is involved in the selection of neuronal precursor cells.


:

Pssm-ID: 462489 [Multi-domain]  Cd Length: 237  Bit Score: 372.16  E-value: 6.79e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767913177  621 YRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSS 700
Cdd:pfam08474   1 YRNNVPTTTPRANLAKELEKYSKTSFDYASFDAQVFGKRTLAPKVQGQDTSPKGFDAKKYFCKPSSPSSSLTSSYAPSSS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767913177  701 SNLscgggssasstcsKSSFDYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCaTRNPDMEVDENGTLDLSMNKQ 780
Cdd:pfam08474  81 SSS-------------SSSYDYTHDMEAAHMAATAILNLSTRCREMPENLSTKPQDLS-AKPDDIEVDENGTLDLSMKKN 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767913177  781 RPRD-SCCPILTPLEPMSPQQQAVM-NNRCFQLGEG-DCWDLPVDYTKMKprRIDEDESKDitPEDLDPFQEALEERRYP 857
Cdd:pfam08474 147 RPRGvTSGSVLTPLPPMSPQRQASLlNSRCYQALCAqDCWDLPVDYTKIK--RIDEEEKEE--PEDLDPFQELLEERKYP 222

                         250
                  ....*....|....*
gi 767913177  858 GEVTIPSPKPKYPQC 872
Cdd:pfam08474 223 GEVTIPSPKPKYPPC 237
zf-C2HC pfam01530
Zinc finger, C2HC type; This is a DNA binding zinc finger domain.
 31-58 3.73e-16

Zinc finger, C2HC type; This is a DNA binding zinc finger domain.


:

Pssm-ID: 460240  Cd Length: 29  Bit Score: 72.57  E-value: 3.73e-16
                          10        20
                  ....*....|....*....|....*...
gi 767913177   31 CPTPGCDGSGHVSGKYARHRSVYGCPLA 58
Cdd:pfam01530   2 CPTPGCDGSGHVSGKYATHRSLSGCPYA 29
zf-C2HC pfam01530
Zinc finger, C2HC type; This is a DNA binding zinc finger domain.
 505-531 1.93e-14

Zinc finger, C2HC type; This is a DNA binding zinc finger domain.


:

Pssm-ID: 460240  Cd Length: 29  Bit Score: 67.56  E-value: 1.93e-14
                          10        20
                  ....*....|....*....|....*..
gi 767913177  505 KCPTPGCDGTGHVTGLYPHHRSLSGCP 531
Cdd:pfam01530   1 KCPTPGCDGSGHVSGKYATHRSLSGCP 27
zf-C2HC pfam01530
Zinc finger, C2HC type; This is a DNA binding zinc finger domain.
 549-577 1.97e-14

Zinc finger, C2HC type; This is a DNA binding zinc finger domain.


:

Pssm-ID: 460240  Cd Length: 29  Bit Score: 67.56  E-value: 1.97e-14
                          10        20
                  ....*....|....*....|....*....
gi 767913177  549 KCPTPGCTGRGHVNSNRNSHRSLSGCPIA 577
Cdd:pfam01530   1 KCPTPGCDGSGHVSGKYATHRSLSGCPYA 29
 
Name Accession Description Interval E-value
MYT1 pfam08474
Myelin transcription factor 1; This domain is found in the myelin transcription factor 1 (MYT1) ...
 621-872 6.79e-123

Myelin transcription factor 1; This domain is found in the myelin transcription factor 1 (MYT1) of chordates. MYT1 contains C2HC zinc finger domains (pfam01530) and is expressed in developing neurons of the central nervous system where it is involved in the selection of neuronal precursor cells.


Pssm-ID: 462489 [Multi-domain]  Cd Length: 237  Bit Score: 372.16  E-value: 6.79e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767913177  621 YRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSS 700
Cdd:pfam08474   1 YRNNVPTTTPRANLAKELEKYSKTSFDYASFDAQVFGKRTLAPKVQGQDTSPKGFDAKKYFCKPSSPSSSLTSSYAPSSS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767913177  701 SNLscgggssasstcsKSSFDYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCaTRNPDMEVDENGTLDLSMNKQ 780
Cdd:pfam08474  81 SSS-------------SSSYDYTHDMEAAHMAATAILNLSTRCREMPENLSTKPQDLS-AKPDDIEVDENGTLDLSMKKN 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767913177  781 RPRD-SCCPILTPLEPMSPQQQAVM-NNRCFQLGEG-DCWDLPVDYTKMKprRIDEDESKDitPEDLDPFQEALEERRYP 857
Cdd:pfam08474 147 RPRGvTSGSVLTPLPPMSPQRQASLlNSRCYQALCAqDCWDLPVDYTKIK--RIDEEEKEE--PEDLDPFQELLEERKYP 222

                         250
                  ....*....|....*
gi 767913177  858 GEVTIPSPKPKYPQC 872
Cdd:pfam08474 223 GEVTIPSPKPKYPPC 237
zf-C2HC pfam01530
Zinc finger, C2HC type; This is a DNA binding zinc finger domain.
 31-58 3.73e-16

Zinc finger, C2HC type; This is a DNA binding zinc finger domain.


Pssm-ID: 460240  Cd Length: 29  Bit Score: 72.57  E-value: 3.73e-16
                          10        20
                  ....*....|....*....|....*...
gi 767913177   31 CPTPGCDGSGHVSGKYARHRSVYGCPLA 58
Cdd:pfam01530   2 CPTPGCDGSGHVSGKYATHRSLSGCPYA 29
zf-C2HC pfam01530
Zinc finger, C2HC type; This is a DNA binding zinc finger domain.
 505-531 1.93e-14

Zinc finger, C2HC type; This is a DNA binding zinc finger domain.


Pssm-ID: 460240  Cd Length: 29  Bit Score: 67.56  E-value: 1.93e-14
                          10        20
                  ....*....|....*....|....*..
gi 767913177  505 KCPTPGCDGTGHVTGLYPHHRSLSGCP 531
Cdd:pfam01530   1 KCPTPGCDGSGHVSGKYATHRSLSGCP 27
zf-C2HC pfam01530
Zinc finger, C2HC type; This is a DNA binding zinc finger domain.
 549-577 1.97e-14

Zinc finger, C2HC type; This is a DNA binding zinc finger domain.


Pssm-ID: 460240  Cd Length: 29  Bit Score: 67.56  E-value: 1.97e-14
                          10        20
                  ....*....|....*....|....*....
gi 767913177  549 KCPTPGCTGRGHVNSNRNSHRSLSGCPIA 577
Cdd:pfam01530   1 KCPTPGCDGSGHVSGKYATHRSLSGCPYA 29
 
Name Accession Description Interval E-value
MYT1 pfam08474
Myelin transcription factor 1; This domain is found in the myelin transcription factor 1 (MYT1) ...
 621-872 6.79e-123

Myelin transcription factor 1; This domain is found in the myelin transcription factor 1 (MYT1) of chordates. MYT1 contains C2HC zinc finger domains (pfam01530) and is expressed in developing neurons of the central nervous system where it is involved in the selection of neuronal precursor cells.


Pssm-ID: 462489 [Multi-domain]  Cd Length: 237  Bit Score: 372.16  E-value: 6.79e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767913177  621 YRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSS 700
Cdd:pfam08474   1 YRNNVPTTTPRANLAKELEKYSKTSFDYASFDAQVFGKRTLAPKVQGQDTSPKGFDAKKYFCKPSSPSSSLTSSYAPSSS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767913177  701 SNLscgggssasstcsKSSFDYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCaTRNPDMEVDENGTLDLSMNKQ 780
Cdd:pfam08474  81 SSS-------------SSSYDYTHDMEAAHMAATAILNLSTRCREMPENLSTKPQDLS-AKPDDIEVDENGTLDLSMKKN 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767913177  781 RPRD-SCCPILTPLEPMSPQQQAVM-NNRCFQLGEG-DCWDLPVDYTKMKprRIDEDESKDitPEDLDPFQEALEERRYP 857
Cdd:pfam08474 147 RPRGvTSGSVLTPLPPMSPQRQASLlNSRCYQALCAqDCWDLPVDYTKIK--RIDEEEKEE--PEDLDPFQELLEERKYP 222

                         250
                  ....*....|....*
gi 767913177  858 GEVTIPSPKPKYPQC 872
Cdd:pfam08474 223 GEVTIPSPKPKYPPC 237
zf-C2HC pfam01530
Zinc finger, C2HC type; This is a DNA binding zinc finger domain.
 31-58 3.73e-16

Zinc finger, C2HC type; This is a DNA binding zinc finger domain.


Pssm-ID: 460240  Cd Length: 29  Bit Score: 72.57  E-value: 3.73e-16
                          10        20
                  ....*....|....*....|....*...
gi 767913177   31 CPTPGCDGSGHVSGKYARHRSVYGCPLA 58
Cdd:pfam01530   2 CPTPGCDGSGHVSGKYATHRSLSGCPYA 29
zf-C2HC pfam01530
Zinc finger, C2HC type; This is a DNA binding zinc finger domain.
 505-531 1.93e-14

Zinc finger, C2HC type; This is a DNA binding zinc finger domain.


Pssm-ID: 460240  Cd Length: 29  Bit Score: 67.56  E-value: 1.93e-14
                          10        20
                  ....*....|....*....|....*..
gi 767913177  505 KCPTPGCDGTGHVTGLYPHHRSLSGCP 531
Cdd:pfam01530   1 KCPTPGCDGSGHVSGKYATHRSLSGCP 27
zf-C2HC pfam01530
Zinc finger, C2HC type; This is a DNA binding zinc finger domain.
 549-577 1.97e-14

Zinc finger, C2HC type; This is a DNA binding zinc finger domain.


Pssm-ID: 460240  Cd Length: 29  Bit Score: 67.56  E-value: 1.97e-14
                          10        20
                  ....*....|....*....|....*....
gi 767913177  549 KCPTPGCTGRGHVNSNRNSHRSLSGCPIA 577
Cdd:pfam01530   1 KCPTPGCDGSGHVSGKYATHRSLSGCPYA 29
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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