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H2-Q8 histocompatibility 2, Q region locus 8 [ Mus musculus (house mouse) ]

Gene ID: 15019, discontinued on 26-Sep-2023

Summary

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Official Symbol
H2-Q8provided by MGI
Official Full Name
histocompatibility 2, Q region locus 8provided by MGI
Primary source
MGI:MGI:95937
Gene type
protein coding
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Qa8; Qa-2; Qa-8; H-2Q8; Ms10t; Gm53175; MMS10-T
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Genomic context

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Location:
17 B1; 17
Exon count:
5
Annotation release Status Assembly Chr Location
108.20200622 latest, but not current GRCm38.p6 (GCF_000001635.26) 17 Unlocalized Scaffold (129X1/SvJ) NT_039662.3 (1642938..1675706)

Genomic regions, transcripts, and products

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Genomic Sequence:
NT_039662.3 Chromosome 17 Reference GRCm38.p6 129X1/SvJ

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The role of structurally conserved class I MHC in tumor rejection: contribution of the Q8 locus. Chiang EY, et al. J Immunol, 2006 Aug 15. PMID 16887971
  2. Two "Qa" specificities: Qa-m7 and Qa-m8 defined by monoclonal antibodies. Sandrin MS, et al. J Immunol, 1983 Aug. PMID 6190932
  3. Expression of the Q8/9d gene by T cells of the mouse. Matsuura A, et al. Immunogenetics, 1989. PMID 2789189
  4. Novel mRNA species from a Q-subregion class-I gene of the murine major histocompatibility complex. Elliott E, et al. Gene, 1987. PMID 3443307
  5. Duplicated gene pairs and alleles of class I genes in the Qa2 region of the murine major histocompatibility complex: a comparison. Devlin JJ, et al. EMBO J, 1985 Dec 1. PMID 3004940, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

General protein information

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Names
histocompatibility 2, Q region locus 8
H-2 class I histocompatibility antigen, Q8 alpha chain
histocompatibility 2, Q region locus 6-like
minisatellite 10t detected by probe MMS10

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mus musculus Updated Annotation Release 108. (NOTE: not current)

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 129X1/SvJ

Genomic

  1. NT_039662.3 Reference GRCm38.p6 129X1/SvJ

    Range
    1642938..1675706
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_023124.5 → NP_075613.3  

    See identical proteins and their annotated locations for NP_075613.3

    Conserved Domains (2) summary
    cd07698
    Location:204 → 296
    IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
    pfam00129
    Location:22 → 200
    MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P14430.1 GenPept UniProtKB/Swiss-Prot:P14430

Gene LinkOut

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