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lama2 laminin, alpha 2 [ Plectropomus leopardus (leopard coralgrouper) ]

Gene ID: 121955856, updated on 22-Mar-2024

Summary

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Gene symbol
lama2
Gene description
laminin, alpha 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Plectropomus leopardus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Perciformes; Serranoidei; Serranidae; Epinephelinae; Epinephelini; Plectropomus
Orthologs
human zebrafish all
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Genomic context

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See lama2 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
74
Annotation release Status Assembly Chr Location
100 current YSFRI_Pleo_2.0 (GCF_008729295.1) 16 NC_056478.1 (18728805..18927501)

Chromosome 16 - NC_056478.1Genomic Context describing neighboring genes Neighboring gene receptor-type tyrosine-protein phosphatase kappa-like Neighboring gene vesicular inhibitory amino acid transporter-like Neighboring gene regulator of G protein signaling 6 Neighboring gene signal-induced proliferation-associated 1 like 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056478.1 Chromosome 16 Reference YSFRI_Pleo_2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of embryonic development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
laminin subunit alpha-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Plectropomus leopardus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference YSFRI_Pleo_2.0 Primary Assembly

Genomic

  1. NC_056478.1 Reference YSFRI_Pleo_2.0 Primary Assembly

    Range
    18728805..18927501
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042503943.1 → XP_042359877.1  laminin subunit alpha-2

    Conserved Domains (10) summary
    smart00136
    Location:10 → 261
    LamNT; Laminin N-terminal domain (domain VI)
    smart00180
    Location:941 → 985
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1202 → 1331
    LamB; Laminin B domain
    smart00282
    Location:2142 → 2284
    LamG; Laminin G domain
    COG1196
    Location:1766 → 2108
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:987 → 1032
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2982 → 3133
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1571 → 1824
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2024 → 2145
    Laminin_II; Laminin Domain II
    cl02548
    Location:551 → 684
    Laminin_B; Laminin B (Domain IV)
Nucleotide Protein
Heading Accession and Version

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