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LAMA2 laminin subunit alpha 2 [ Mauremys reevesii (Reeves's turtle) ]

Gene ID: 120400335, updated on 21-Mar-2024

Summary

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Gene symbol
LAMA2
Gene description
laminin subunit alpha 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Mauremys reevesii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Testudinoidea; Geoemydidae; Geoemydinae; Mauremys
Orthologs
human mouse all
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Genomic context

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See LAMA2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
69
Annotation release Status Assembly LG Location
100 current ASM1616193v1 (GCF_016161935.1) 3 NC_052625.1 (113187684..113664994, complement)

Linkage Group 3 - NC_052625.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 244 Neighboring gene Rho GTPase activating protein 18 Neighboring gene uncharacterized LOC120400338 Neighboring gene uncharacterized LOC120400337 Neighboring gene vesicular inhibitory amino acid transporter-like Neighboring gene U2 spliceosomal RNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_052625.1 Chromosome 3 Reference ASM1616193v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of embryonic development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
laminin subunit alpha-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mauremys reevesii Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1616193v1 Primary Assembly

Genomic

  1. NC_052625.1 Reference ASM1616193v1 Primary Assembly

    Range
    113187684..113664994 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039528773.1 → XP_039384707.1  laminin subunit alpha-2 isoform X13

    Conserved Domains (10) summary
    smart00180
    Location:968 → 1012
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1683 → 2022
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:918 → 966
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2957 → 3109
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1594 → 1851
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2038 → 2172
    Laminin_II; Laminin Domain II
    pfam00052
    Location:1235 → 1379
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1421 → 1467
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2809 → 2928
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:40 → 286
    Laminin_N; Laminin N-terminal (Domain VI)

  2. XM_039528772.1 → XP_039384706.1  laminin subunit alpha-2 isoform X12

    Conserved Domains (10) summary
    smart00180
    Location:968 → 1012
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1683 → 2022
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:918 → 966
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2961 → 3113
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1594 → 1851
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2038 → 2172
    Laminin_II; Laminin Domain II
    pfam00052
    Location:1235 → 1379
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1421 → 1467
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2813 → 2932
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:40 → 286
    Laminin_N; Laminin N-terminal (Domain VI)

  3. XM_039528762.1 → XP_039384696.1  laminin subunit alpha-2 isoform X3

    Conserved Domains (10) summary
    smart00136
    Location:35 → 286
    LamNT; Laminin N-terminal domain (domain VI)
    smart00180
    Location:968 → 1012
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1683 → 2022
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:918 → 966
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2981 → 3133
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1594 → 1851
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2038 → 2172
    Laminin_II; Laminin Domain II
    pfam00052
    Location:1235 → 1379
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1421 → 1467
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2833 → 2952
    Laminin_G_1; Laminin G domain

  4. XM_039528768.1 → XP_039384702.1  laminin subunit alpha-2 isoform X9

    Conserved Domains (10) summary
    smart00136
    Location:35 → 286
    LamNT; Laminin N-terminal domain (domain VI)
    smart00180
    Location:986 → 1030
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1609 → 1948
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:936 → 984
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2907 → 3059
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1520 → 1777
    Laminin_I; Laminin Domain I
    pfam06009
    Location:1964 → 2098
    Laminin_II; Laminin Domain II
    pfam00052
    Location:1161 → 1305
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1347 → 1393
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2759 → 2878
    Laminin_G_1; Laminin G domain

  5. XM_039528765.1 → XP_039384699.1  laminin subunit alpha-2 isoform X6

    Conserved Domains (10) summary
    smart00136
    Location:35 → 286
    LamNT; Laminin N-terminal domain (domain VI)
    smart00180
    Location:986 → 1030
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1656 → 1995
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:936 → 984
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2954 → 3106
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1567 → 1824
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2011 → 2145
    Laminin_II; Laminin Domain II
    pfam00052
    Location:1253 → 1397
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1079 → 1127
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2806 → 2925
    Laminin_G_1; Laminin G domain

  6. XM_039528766.1 → XP_039384700.1  laminin subunit alpha-2 isoform X7

    Conserved Domains (10) summary
    smart00136
    Location:35 → 286
    LamNT; Laminin N-terminal domain (domain VI)
    smart00180
    Location:986 → 1030
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1655 → 1994
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:936 → 984
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2953 → 3105
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1566 → 1823
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2010 → 2144
    Laminin_II; Laminin Domain II
    pfam00052
    Location:1253 → 1397
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1439 → 1485
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2805 → 2924
    Laminin_G_1; Laminin G domain

  7. XM_039528764.1 → XP_039384698.1  laminin subunit alpha-2 isoform X5

    Conserved Domains (10) summary
    smart00180
    Location:986 → 1030
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1701 → 2040
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:936 → 984
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2975 → 3127
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1612 → 1869
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2056 → 2190
    Laminin_II; Laminin Domain II
    pfam00052
    Location:1253 → 1397
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1439 → 1485
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2827 → 2946
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:40 → 286
    Laminin_N; Laminin N-terminal (Domain VI)

  8. XM_039528761.1 → XP_039384695.1  laminin subunit alpha-2 isoform X2

    Conserved Domains (10) summary
    smart00136
    Location:35 → 286
    LamNT; Laminin N-terminal domain (domain VI)
    smart00180
    Location:986 → 1030
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1701 → 2040
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:936 → 984
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2995 → 3147
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1612 → 1869
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2056 → 2190
    Laminin_II; Laminin Domain II
    pfam00052
    Location:1253 → 1397
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1439 → 1485
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2847 → 2966
    Laminin_G_1; Laminin G domain

  9. XM_039528763.1 → XP_039384697.1  laminin subunit alpha-2 isoform X4

    Conserved Domains (10) summary
    smart00180
    Location:986 → 1030
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1701 → 2040
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:936 → 984
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2979 → 3131
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1612 → 1869
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2056 → 2190
    Laminin_II; Laminin Domain II
    pfam00052
    Location:1253 → 1397
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1439 → 1485
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2831 → 2950
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:40 → 286
    Laminin_N; Laminin N-terminal (Domain VI)

  10. XM_039528760.1 → XP_039384694.1  laminin subunit alpha-2 isoform X1

    Conserved Domains (10) summary
    smart00136
    Location:35 → 286
    LamNT; Laminin N-terminal domain (domain VI)
    smart00180
    Location:986 → 1030
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1701 → 2040
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:936 → 984
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2999 → 3151
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1612 → 1869
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2056 → 2190
    Laminin_II; Laminin Domain II
    pfam00052
    Location:1253 → 1397
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1439 → 1485
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2851 → 2970
    Laminin_G_1; Laminin G domain

  11. XM_039528767.1 → XP_039384701.1  laminin subunit alpha-2 isoform X8

    Conserved Domains (10) summary
    smart00180
    Location:922 → 966
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1637 → 1976
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:872 → 920
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2935 → 3087
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1548 → 1805
    Laminin_I; Laminin Domain I
    pfam06009
    Location:1992 → 2126
    Laminin_II; Laminin Domain II
    pfam00052
    Location:1189 → 1333
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1375 → 1421
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2787 → 2906
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:2 → 222
    Laminin_N; Laminin N-terminal (Domain VI)

  12. XM_039528771.1 → XP_039384705.1  laminin subunit alpha-2 isoform X11

    Conserved Domains (9) summary
    smart00180
    Location:395 → 439
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1110 → 1449
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:345 → 393
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2408 → 2560
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1021 → 1278
    Laminin_I; Laminin Domain I
    pfam06009
    Location:1465 → 1599
    Laminin_II; Laminin Domain II
    pfam00052
    Location:662 → 806
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:848 → 894
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2260 → 2379
    Laminin_G_1; Laminin G domain

  13. XM_039528769.1 → XP_039384703.1  laminin subunit alpha-2 isoform X10

    Conserved Domains (10) summary
    smart00180
    Location:986 → 1030
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1701 → 2040
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:936 → 982
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2545 → 2707
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1612 → 1869
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2056 → 2190
    Laminin_II; Laminin Domain II
    pfam00052
    Location:1253 → 1397
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1439 → 1485
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2385 → 2524
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:40 → 286
    Laminin_N; Laminin N-terminal (Domain VI)
Nucleotide Protein
Heading Accession and Version

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