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LAMA2 laminin subunit alpha 2 [ Dermochelys coriacea (leatherback sea turtle) ]

Gene ID: 119853872, updated on 8-May-2024

Summary

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Gene symbol
LAMA2
Gene description
laminin subunit alpha 2
See related
EnsemblRapid:ENSDCOG00030007075
Gene type
protein coding
RefSeq status
MODEL
Organism
Dermochelys coriacea
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Americhelydia; Chelonioidea; Dermochelyidae; Dermochelys
Orthologs
human mouse all
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Genomic context

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See LAMA2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
64
Annotation release Status Assembly Chr Location
101 current rDerCor1.pri.v4 (GCF_009764565.3) 3 NC_050070.1 (99535874..100028437)
100 previous assembly rDerCor1.pri.v3 (GCF_009764565.2) 3 NC_050070.1 (99535827..100028313)

Chromosome 3 - NC_050070.1Genomic Context describing neighboring genes Neighboring gene vesicular inhibitory amino acid transporter-like Neighboring gene uncharacterized LOC122459095 Neighboring gene Rho GTPase activating protein 18 Neighboring gene transmembrane protein 244

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of embryonic development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
laminin subunit alpha-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Dermochelys coriacea Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference rDerCor1.pri.v4

Genomic

  1. NC_050070.1 Reference rDerCor1.pri.v4

    Range
    99535874..100028437
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038397415.2 → XP_038253343.1  laminin subunit alpha-2 isoform X1

    Conserved Domains (10) summary
    smart00180
    Location:962 → 1006
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1677 → 2019
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:912 → 960
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2951 → 3103
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1588 → 1844
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2032 → 2166
    Laminin_II; Laminin Domain II
    pfam00052
    Location:1229 → 1373
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1055 → 1103
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2803 → 2921
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:34 → 280
    Laminin_N; Laminin N-terminal (Domain VI)

  2. XM_043510932.1 → XP_043366867.1  laminin subunit alpha-2 isoform X2

    Related
    ENSDCOP00030026518.1, ENSDCOT00030027760.1
    Conserved Domains (10) summary
    smart00136
    Location:31 → 280
    LamNT; Laminin N-terminal domain (domain VI)
    smart00180
    Location:962 → 1006
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1226 → 1359
    LamB; Laminin B domain
    smart00282
    Location:2162 → 2304
    LamG; Laminin G domain
    COG1196
    Location:1677 → 2019
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:912 → 960
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2772 → 2921
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1588 → 1844
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2032 → 2166
    Laminin_II; Laminin Domain II
    cl02548
    Location:577 → 705
    Laminin_B; Laminin B (Domain IV)
Nucleotide Protein
Heading Accession and Version

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