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LAMA2 laminin subunit alpha 2 [ Myotis myotis ]

Gene ID: 118659861, updated on 30-Mar-2024

Summary

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Gene symbol
LAMA2
Gene description
laminin subunit alpha 2
Locus tag
mMyoMyo1_011899
Gene type
protein coding
RefSeq status
MODEL
Organism
Myotis myotis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Myotis
Orthologs
human mouse all
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Genomic context

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See LAMA2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
66
Annotation release Status Assembly Chr Location
100 current mMyoMyo1.p (GCF_014108235.1) Unplaced Scaffold NW_023416379.1 (19185627..19665648)

NW_023416379.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene elongation factor 1-alpha 1-like Neighboring gene 60S acidic ribosomal protein P1-like Neighboring gene U6 spliceosomal RNA Neighboring gene Rho GTPase activating protein 18 Neighboring gene single-stranded DNA-binding protein 2-like Neighboring gene protein-associating with the carboxyl-terminal domain of ezrin-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_023416379 Unplaced Scaffold Reference mMyoMyo1.p Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of embryonic development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
laminin subunit alpha-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Myotis myotis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mMyoMyo1.p Primary Assembly

Genomic

  1. NW_023416379.1 Reference mMyoMyo1.p Primary Assembly

    Range
    19185627..19665648
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036316421.1 → XP_036172314.1  laminin subunit alpha-2 isoform X7

    UniProtKB/TrEMBL
    A0A7J7WVQ1
    Conserved Domains (10) summary
    smart00180
    Location:991 → 1035
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1253 → 1388
    LamB; Laminin B domain
    COG3883
    Location:1820 → 2078
    CwlO1; Uncharacterized N-terminal domain of peptidoglycan hydrolase CwlO [Function unknown]
    cd00055
    Location:941 → 989
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam06008
    Location:1619 → 1876
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2061 → 2197
    Laminin_II; Laminin Domain II
    pfam00052
    Location:587 → 728
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1084 → 1132
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2392 → 2531
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:45 → 290
    Laminin_N; Laminin N-terminal (Domain VI)

  2. XM_036316415.1 → XP_036172308.1  laminin subunit alpha-2 isoform X2

    UniProtKB/TrEMBL
    A0A7J7WVQ1
    Conserved Domains (11) summary
    smart00180
    Location:991 → 1035
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1253 → 1388
    LamB; Laminin B domain
    COG3883
    Location:1820 → 2078
    CwlO1; Uncharacterized N-terminal domain of peptidoglycan hydrolase CwlO [Function unknown]
    cd00055
    Location:941 → 989
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2958 → 3110
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1619 → 1876
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2061 → 2197
    Laminin_II; Laminin Domain II
    pfam00052
    Location:587 → 728
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1130 → 1187
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2810 → 2938
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:45 → 290
    Laminin_N; Laminin N-terminal (Domain VI)

  3. XM_036316414.1 → XP_036172307.1  laminin subunit alpha-2 isoform X1

    UniProtKB/TrEMBL
    A0A7J7WVQ1
    Conserved Domains (11) summary
    smart00180
    Location:991 → 1035
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1253 → 1388
    LamB; Laminin B domain
    COG3883
    Location:1820 → 2078
    CwlO1; Uncharacterized N-terminal domain of peptidoglycan hydrolase CwlO [Function unknown]
    cd00055
    Location:941 → 989
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2962 → 3114
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1619 → 1876
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2061 → 2197
    Laminin_II; Laminin Domain II
    pfam00052
    Location:587 → 728
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1130 → 1187
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2814 → 2942
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:45 → 290
    Laminin_N; Laminin N-terminal (Domain VI)

  4. XM_036316418.1 → XP_036172311.1  laminin subunit alpha-2 isoform X5

    UniProtKB/TrEMBL
    A0A7J7WWB2
    Conserved Domains (11) summary
    smart00180
    Location:991 → 1035
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1253 → 1388
    LamB; Laminin B domain
    COG3883
    Location:1774 → 2032
    CwlO1; Uncharacterized N-terminal domain of peptidoglycan hydrolase CwlO [Function unknown]
    cd00055
    Location:941 → 989
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2916 → 3068
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1573 → 1830
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2015 → 2151
    Laminin_II; Laminin Domain II
    pfam00052
    Location:587 → 728
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1130 → 1187
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2768 → 2896
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:45 → 290
    Laminin_N; Laminin N-terminal (Domain VI)

  5. XM_036316416.1 → XP_036172309.1  laminin subunit alpha-2 isoform X3

    UniProtKB/TrEMBL
    A0A7J7WVQ6
    Conserved Domains (11) summary
    smart00180
    Location:973 → 1017
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1235 → 1370
    LamB; Laminin B domain
    COG3883
    Location:1802 → 2060
    CwlO1; Uncharacterized N-terminal domain of peptidoglycan hydrolase CwlO [Function unknown]
    cd00055
    Location:923 → 971
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2944 → 3096
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1601 → 1858
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2043 → 2179
    Laminin_II; Laminin Domain II
    pfam00052
    Location:587 → 728
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1112 → 1169
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2796 → 2924
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:45 → 290
    Laminin_N; Laminin N-terminal (Domain VI)

  6. XM_036316417.1 → XP_036172310.1  laminin subunit alpha-2 isoform X4

    UniProtKB/TrEMBL
    A0A7J7WVQ6
    Conserved Domains (11) summary
    smart00180
    Location:973 → 1017
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1235 → 1370
    LamB; Laminin B domain
    COG3883
    Location:1802 → 2060
    CwlO1; Uncharacterized N-terminal domain of peptidoglycan hydrolase CwlO [Function unknown]
    cd00055
    Location:923 → 971
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2940 → 3092
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1601 → 1858
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2043 → 2179
    Laminin_II; Laminin Domain II
    pfam00052
    Location:587 → 728
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1112 → 1169
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2792 → 2920
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:45 → 290
    Laminin_N; Laminin N-terminal (Domain VI)

  7. XM_036316419.1 → XP_036172312.1  laminin subunit alpha-2 isoform X6

    UniProtKB/TrEMBL
    A0A7J7WVQ6
    Conserved Domains (11) summary
    smart00180
    Location:935 → 979
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1197 → 1332
    LamB; Laminin B domain
    COG3883
    Location:1764 → 2022
    CwlO1; Uncharacterized N-terminal domain of peptidoglycan hydrolase CwlO [Function unknown]
    cd00055
    Location:885 → 933
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2906 → 3058
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1563 → 1820
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2005 → 2141
    Laminin_II; Laminin Domain II
    pfam00052
    Location:587 → 728
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1074 → 1131
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2758 → 2886
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:45 → 290
    Laminin_N; Laminin N-terminal (Domain VI)
Nucleotide Protein
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