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lama1 laminin, alpha 1 [ Cyclopterus lumpus (lumpfish) ]

Gene ID: 117749872, updated on 19-Mar-2024

Summary

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Gene symbol
lama1
Gene description
laminin, alpha 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Cyclopterus lumpus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Perciformes; Cottioidei; Cottales; Cyclopteridae; Cyclopterus
Orthologs
human zebrafish all
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Genomic context

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See lama1 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
64
Annotation release Status Assembly Chr Location
100 current fCycLum1.pri (GCF_009769545.1) 20 NC_046985.1 (709934..786194, complement)

Chromosome 20 - NC_046985.1Genomic Context describing neighboring genes Neighboring gene piezo-type mechanosensitive ion channel component 2-like Neighboring gene protein 4.1-like Neighboring gene activin receptor type-2B-like Neighboring gene xylulokinase homolog (H. influenzae)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_046985.1 Chromosome 20 Reference fCycLum1.pri

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in blood vessel morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in camera-type eye development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of embryonic development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
laminin subunit alpha-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cyclopterus lumpus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fCycLum1.pri

Genomic

  1. NC_046985.1 Reference fCycLum1.pri

    Range
    709934..786194 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_034560689.1 → XP_034416580.1  laminin subunit alpha-1

    Conserved Domains (9) summary
    smart00136
    Location:16 → 266
    LamNT; Laminin N-terminal domain (domain VI)
    smart00282
    Location:2125 → 2265
    LamG; Laminin G domain
    cd00055
    Location:889 → 936
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2292 → 2448
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1558 → 1813
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2006 → 2128
    Laminin_II; Laminin Domain II
    pfam00052
    Location:1202 → 1342
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1031 → 1079
    Laminin_EGF; Laminin EGF domain
    pfam02210
    Location:2498 → 2635
    Laminin_G_2; Laminin G domain
Nucleotide Protein
Heading Accession and Version

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