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lama1 laminin, alpha 1 [ Xiphophorus hellerii (green swordtail) ]

Gene ID: 116711857, updated on 18-Mar-2024

Summary

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Gene symbol
lama1
Gene description
laminin, alpha 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Xiphophorus hellerii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Xiphophorus
Orthologs
human zebrafish all
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Genomic context

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See lama1 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
64
Annotation release Status Assembly Chr Location
100 current Xiphophorus_hellerii-4.1 (GCF_003331165.1) 21 NC_045692.1 (26005204..26036196)

Chromosome 21 - NC_045692.1Genomic Context describing neighboring genes Neighboring gene crystallin, gamma N2 Neighboring gene enoyl-CoA delta isomerase 2 Neighboring gene erythrocyte membrane protein band 4.1-like 3a Neighboring gene uncharacterized LOC116711865 Neighboring gene transmembrane protein 200C, genome duplicate a Neighboring gene lethal(3)malignant brain tumor-like protein 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_045692.1 Chromosome 21 Reference Xiphophorus_hellerii-4.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in blood vessel morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in camera-type eye development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of embryonic development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
laminin subunit alpha-1
Names
laminin subunit alpha 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xiphophorus hellerii Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xiphophorus_hellerii-4.1 Primary Assembly

Genomic

  1. NC_045692.1 Reference Xiphophorus_hellerii-4.1 Primary Assembly

    Range
    26005204..26036196
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032551424.1 → XP_032407315.1  laminin subunit alpha-1 isoform X1

    Conserved Domains (11) summary
    smart00136
    Location:20 → 268
    LamNT; Laminin N-terminal domain (domain VI)
    smart00180
    Location:939 → 983
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00282
    Location:2125 → 2265
    LamG; Laminin G domain
    cd00055
    Location:836 → 888
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2292 → 2448
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR02168
    Location:1753 → 2106
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06008
    Location:1558 → 1796
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2033 → 2125
    Laminin_II; Laminin Domain II
    pfam00052
    Location:1202 → 1343
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1032 → 1080
    Laminin_EGF; Laminin EGF domain
    cl02548
    Location:559 → 698
    Laminin_B; Laminin B (Domain IV)

  2. XM_032551426.1 → XP_032407317.1  laminin subunit alpha-1 isoform X3

    Conserved Domains (11) summary
    smart00136
    Location:20 → 268
    LamNT; Laminin N-terminal domain (domain VI)
    smart00180
    Location:939 → 983
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00282
    Location:2101 → 2217
    LamG; Laminin G domain
    cd00055
    Location:836 → 888
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2244 → 2400
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR02168
    Location:1753 → 2099
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06008
    Location:1558 → 1796
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2033 → 2115
    Laminin_II; Laminin Domain II
    pfam00052
    Location:1202 → 1343
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1032 → 1080
    Laminin_EGF; Laminin EGF domain
    cl02548
    Location:559 → 698
    Laminin_B; Laminin B (Domain IV)

  3. XM_032551425.1 → XP_032407316.1  laminin subunit alpha-1 isoform X2

    Conserved Domains (11) summary
    smart00136
    Location:20 → 268
    LamNT; Laminin N-terminal domain (domain VI)
    smart00180
    Location:939 → 983
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00282
    Location:2124 → 2264
    LamG; Laminin G domain
    cd00055
    Location:836 → 888
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2291 → 2447
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR02168
    Location:1753 → 2105
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06008
    Location:1558 → 1796
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2032 → 2124
    Laminin_II; Laminin Domain II
    pfam00052
    Location:1202 → 1343
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1032 → 1080
    Laminin_EGF; Laminin EGF domain
    cl02548
    Location:559 → 698
    Laminin_B; Laminin B (Domain IV)
Nucleotide Protein Strain
Heading Accession and Version

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