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lama1 laminin, alpha 1 [ Oreochromis aureus ]

Gene ID: 116328709, updated on 18-Jun-2024

Summary

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Gene symbol
lama1
Gene description
laminin, alpha 1
See related
Ensembl:ENSOABG00000011262
Gene type
protein coding
RefSeq status
MODEL
Organism
Oreochromis aureus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini; Oreochromis
Orthologs
human zebrafish all
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Genomic context

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See lama1 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
64
Annotation release Status Assembly LG Location
101 current ZZ_aureus (GCF_013358895.1) 9 NC_052950.1 (5833459..5874578, complement)
100 previous assembly ASM587006v1 (GCF_005870065.1) Unplaced Scaffold NW_022245927.1 (1301833..1340508, complement)

Linkage Group 9 - NC_052950.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 200C-like Neighboring gene erythrocyte membrane protein band 4.1-like 3a Neighboring gene cubilin (intrinsic factor-cobalamin receptor) Neighboring gene tRNA aspartic acid methyltransferase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in blood vessel morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in camera-type eye development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of embryonic development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
laminin subunit alpha-1
Names
laminin subunit alpha 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Oreochromis aureus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ZZ_aureus Primary Assembly

Genomic

  1. NC_052950.1 Reference ZZ_aureus Primary Assembly

    Range
    5833459..5874578 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031750565.2 → XP_031606425.1  laminin subunit alpha-1

    UniProtKB/TrEMBL
    A0A668TJ23
    Related
    ENSOABP00000026698.1, ENSOABT00000027460.2
    Conserved Domains (9) summary
    smart00136
    Location:18 → 266
    LamNT; Laminin N-terminal domain (domain VI)
    smart00180
    Location:987 → 1030
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00282
    Location:2137 → 2277
    LamG; Laminin G domain
    cd00055
    Location:891 → 937
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2304 → 2460
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1569 → 1813
    Laminin_I; Laminin Domain I
    pfam00052
    Location:1208 → 1330
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1033 → 1081
    Laminin_EGF; Laminin EGF domain
    pfam06009
    Location:2016 → 2141
    Laminin_II; Laminin Domain II
Nucleotide Protein Strain
Heading Accession and Version

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