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lama2 laminin, alpha 2 [ Oreochromis aureus ]

Gene ID: 116312764, updated on 18-Jun-2024

Summary

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Gene symbol
lama2
Gene description
laminin, alpha 2
See related
Ensembl:ENSOABG00000025073
Gene type
protein coding
RefSeq status
MODEL
Organism
Oreochromis aureus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini; Oreochromis
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 15
Exon count:
74
Annotation release Status Assembly LG Location
101 current ZZ_aureus (GCF_013358895.1) 15 NC_052956.1 (15898443..16100912)
100 previous assembly ASM587006v1 (GCF_005870065.1) Unplaced Scaffold NW_022247213.1 (1679267..1881248)

Linkage Group 15 - NC_052956.1Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase receptor type K Neighboring gene uncharacterized LOC120433135 Neighboring gene vesicular inhibitory amino acid transporter Neighboring gene uncharacterized LOC120433273 Neighboring gene regulator of G protein signaling 6 Neighboring gene signal-induced proliferation-associated 1 like 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of embryonic development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
laminin subunit alpha-2
Names
laminin subunit alpha 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Oreochromis aureus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ZZ_aureus Primary Assembly

Genomic

  1. NC_052956.1 Reference ZZ_aureus Primary Assembly

    Range
    15898443..16100912
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039599289.1 → XP_039455223.1  laminin subunit alpha-2 isoform X1

    UniProtKB/TrEMBL
    A0A668W2R2
    Conserved Domains (10) summary
    smart00136
    Location:20 → 270
    LamNT; Laminin N-terminal domain (domain VI)
    smart00180
    Location:950 → 994
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1211 → 1340
    LamB; Laminin B domain
    smart00282
    Location:2151 → 2293
    LamG; Laminin G domain
    COG1196
    Location:1745 → 2143
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:996 → 1041
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2983 → 3134
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1572 → 1832
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2033 → 2154
    Laminin_II; Laminin Domain II
    cl02548
    Location:560 → 693
    Laminin_B; Laminin B (Domain IV)

  2. XM_039599293.1 → XP_039455227.1  laminin subunit alpha-2 isoform X5

    UniProtKB/TrEMBL
    A0A668W2R2
    Conserved Domains (10) summary
    smart00136
    Location:20 → 270
    LamNT; Laminin N-terminal domain (domain VI)
    smart00180
    Location:950 → 994
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1211 → 1340
    LamB; Laminin B domain
    smart00282
    Location:2151 → 2293
    LamG; Laminin G domain
    COG1196
    Location:1745 → 2143
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:996 → 1041
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2952 → 3103
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1572 → 1832
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2033 → 2154
    Laminin_II; Laminin Domain II
    cl02548
    Location:560 → 693
    Laminin_B; Laminin B (Domain IV)

  3. XM_039599291.1 → XP_039455225.1  laminin subunit alpha-2 isoform X3

    UniProtKB/TrEMBL
    A0A668W2R2
    Conserved Domains (10) summary
    smart00136
    Location:20 → 270
    LamNT; Laminin N-terminal domain (domain VI)
    smart00180
    Location:950 → 994
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1211 → 1340
    LamB; Laminin B domain
    smart00282
    Location:2151 → 2293
    LamG; Laminin G domain
    COG1196
    Location:1745 → 2143
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:996 → 1041
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2979 → 3130
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1572 → 1832
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2033 → 2154
    Laminin_II; Laminin Domain II
    cl02548
    Location:560 → 693
    Laminin_B; Laminin B (Domain IV)

  4. XM_039599290.1 → XP_039455224.1  laminin subunit alpha-2 isoform X2

    UniProtKB/TrEMBL
    A0A668W2R2
    Related
    ENSOABP00000056952.2, ENSOABT00000058390.2
    Conserved Domains (10) summary
    smart00136
    Location:20 → 270
    LamNT; Laminin N-terminal domain (domain VI)
    smart00180
    Location:950 → 994
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1211 → 1340
    LamB; Laminin B domain
    smart00282
    Location:2149 → 2291
    LamG; Laminin G domain
    COG1196
    Location:1745 → 2141
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:996 → 1041
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2981 → 3132
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1572 → 1832
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2033 → 2152
    Laminin_II; Laminin Domain II
    cl02548
    Location:560 → 693
    Laminin_B; Laminin B (Domain IV)

  5. XM_039599292.1 → XP_039455226.1  laminin subunit alpha-2 isoform X4

    UniProtKB/TrEMBL
    A0A668W2R2
    Related
    ENSOABP00000056955.2, ENSOABT00000058393.2
    Conserved Domains (10) summary
    smart00136
    Location:20 → 270
    LamNT; Laminin N-terminal domain (domain VI)
    smart00180
    Location:950 → 994
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1211 → 1340
    LamB; Laminin B domain
    smart00282
    Location:2149 → 2291
    LamG; Laminin G domain
    COG1196
    Location:1745 → 2141
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:996 → 1041
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2977 → 3128
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1572 → 1832
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2033 → 2152
    Laminin_II; Laminin Domain II
    cl02548
    Location:560 → 693
    Laminin_B; Laminin B (Domain IV)

  6. XM_039599294.1 → XP_039455228.1  laminin subunit alpha-2 isoform X6

    UniProtKB/TrEMBL
    A0A668VZJ1
    Conserved Domains (10) summary
    smart00136
    Location:20 → 270
    LamNT; Laminin N-terminal domain (domain VI)
    smart00180
    Location:950 → 994
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1211 → 1340
    LamB; Laminin B domain
    smart00282
    Location:2105 → 2247
    LamG; Laminin G domain
    COG1196
    Location:1699 → 2097
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:996 → 1041
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2937 → 3088
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1526 → 1786
    Laminin_I; Laminin Domain I
    pfam06009
    Location:1987 → 2108
    Laminin_II; Laminin Domain II
    cl02548
    Location:560 → 693
    Laminin_B; Laminin B (Domain IV)

  7. XM_039599295.1 → XP_039455229.1  laminin subunit alpha-2 isoform X7

    UniProtKB/TrEMBL
    A0A668VZJ1
    Conserved Domains (10) summary
    smart00136
    Location:20 → 270
    LamNT; Laminin N-terminal domain (domain VI)
    smart00180
    Location:950 → 994
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1211 → 1340
    LamB; Laminin B domain
    smart00282
    Location:2103 → 2245
    LamG; Laminin G domain
    COG1196
    Location:1699 → 2095
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:996 → 1041
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2931 → 3082
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1526 → 1786
    Laminin_I; Laminin Domain I
    pfam06009
    Location:1987 → 2106
    Laminin_II; Laminin Domain II
    cl02548
    Location:560 → 693
    Laminin_B; Laminin B (Domain IV)
Nucleotide Protein Strain
Heading Accession and Version

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