U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

c4b complement C4B (Chido/Rodgers blood group) [ Gadus morhua (Atlantic cod) ]

Gene ID: 115545481, updated on 17-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
c4b
Gene description
complement C4B (Chido/Rodgers blood group)
See related
Ensembl:ENSGMOG00000030068
Gene type
protein coding
RefSeq status
MODEL
Organism
Gadus morhua
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Zeiogadaria; Gadariae; Gadiformes; Gadoidei; Gadidae; Gadus
Orthologs
zebrafish all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See c4b in Genome Data Viewer
Location:
chromosome: 6
Exon count:
41
Annotation release Status Assembly Chr Location
100 current gadMor3.0 (GCF_902167405.1) 6 NC_044053.1 (2125708..2146597, complement)

Chromosome 6 - NC_044053.1Genomic Context describing neighboring genes Neighboring gene complement C4-like Neighboring gene complement C4-like Neighboring gene uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02-like Neighboring gene retinoic acid receptor RXR-beta-A-like

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_044053.1 Chromosome 6 Reference gadMor3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The genome sequence of Atlantic cod reveals a unique immune system. Star B, et al. Nature, 2011 Aug 10. PMID 21832995, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
complement C4-like
Names
complement 4B (Chido blood group)

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Gadus morhua Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference gadMor3.0 Primary Assembly

Genomic

  1. NC_044053.1 Reference gadMor3.0 Primary Assembly

    Range
    2125708..2146597 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030358697.1 → XP_030214557.1  complement C4-like isoform X2

    UniProtKB/TrEMBL
    A0A8C4ZDV5
    Related
    ENSGMOP00000010185.2, ENSGMOT00000010462.2
    Conserved Domains (6) summary
    COG2373
    Location:20 → 1313
    YfaS; Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family [General function prediction only]
    cd02896
    Location:971 → 1282
    complement_C3_C4_C5; Proteins similar to C3, C4 and C5 of vertebrate complement. The vertebrate complement system, comprised of a large number of distinct plasma proteins, is an effector of both the acquired and innate immune systems. The point of convergence of the ...
    pfam00207
    Location:772 → 845
    A2M; Alpha-2-macroglobulin family
    pfam07677
    Location:1427 → 1516
    A2M_recep; A-macroglobulin receptor
    pfam01835
    Location:121 → 215
    A2M_N; MG2 domain
    cl02512
    Location:1534 → 1678
    NTR_like; NTR_like domain; a beta barrel with an oligosaccharide/oligonucleotide-binding fold found in netrins, complement proteins, tissue inhibitors of metalloproteases (TIMP), and procollagen C-proteinase enhancers (PCOLCE), amongst others. In netrins, the ...

  2. XM_030358696.1 → XP_030214556.1  complement C4-like isoform X1

    UniProtKB/TrEMBL
    A0A8C4ZDV5
    Conserved Domains (7) summary
    COG2373
    Location:20 → 1058
    YfaS; Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family [General function prediction only]
    cd02896
    Location:971 → 1293
    complement_C3_C4_C5; Proteins similar to C3, C4 and C5 of vertebrate complement. The vertebrate complement system, comprised of a large number of distinct plasma proteins, is an effector of both the acquired and innate immune systems. The point of convergence of the ...
    pfam00207
    Location:772 → 845
    A2M; Alpha-2-macroglobulin family
    pfam07677
    Location:1438 → 1527
    A2M_recep; A-macroglobulin receptor
    pfam17791
    Location:217 → 303
    MG3; Macroglobulin domain MG3
    pfam01835
    Location:121 → 215
    A2M_N; MG2 domain
    cl02512
    Location:1545 → 1689
    NTR_like; NTR_like domain; a beta barrel with an oligosaccharide/oligonucleotide-binding fold found in netrins, complement proteins, tissue inhibitors of metalloproteases (TIMP), and procollagen C-proteinase enhancers (PCOLCE), amongst others. In netrins, the ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.