20178251 289 DEKKLNAWIHSQPL-MPMDKGGSVhlsinkGVNASVAATPTTQAQNKWVSVPNLYSLAVNSINATLVESDNNNGEraLII 367 Yersinia pestis 20178232 1 ---------------------MSN------LRRFSRSLAVAALVLLPFAAVQAEDTVE---PSGYTPMAGESFFL--LAD 48 Pseudomonas aerug... 20178161 205 GEKDLVAWVNSDNVaLAQSDNQYIevkidkNLTALLGNNSLETDIISSVKVPTKYSLDFS-TGILIAQNEKNEAEqvLHL 283 Pasteurella multo... 20178153 196 NTNNTEATIITNIP-PLTDKEDTIsviikdGVKPLHGGEVFTYKNVKDPNNKTPNNIRYSYKENVLIPSLSSYLK--ITN 272 Rickettsia conorii 15604412 196 NTDNTEAISITNIP-PLTDKKDIVsiiikdGVKILYGDEIFTQKNVDIQNNKMQNNIRYSYKEKVLIPSLSSYFK--ITN 272 Rickettsia prowaz... 20178245 1 -------------------MICLA------ALAVAVPARADEAAAVRDKPNPTLAEVP---ASGYVPFTGQPFFL--LSD 50 Ralstonia solanac... 20178234 1 --------------------------------MGMKRLIFLVFLLISFSLFGGYAYFS---RYPVLHPDEGLSFV--ISD 43 Thermotoga maritima 15802775 1 --------MDTQRF-QSQFHWHLS------FKFSGAIAACLSLSLVGTGLANADDSLP---SSNYAPPAGGTFFL--LAD 60 Escherichia coli ... 20178214 200 KNEGLRFQVTLNKEeKPLDKEEPLkk---fDPSARNWIYNLRPQKNLKTATRYRLVFSPGIRPAYGNLVTDREFVskLST 276 Nostoc sp. PCC 7120 16132271 1 ---------------------------------------------MGTGLANADDSLP---SSNYAPPAGGTFFL--LAD 30 Escherichia coli K12
20178251 368 AISDAVKDkeikNAVKAWLLPqhnfqakESAKTSTDFYP----WDMDDIDDNllqqs--------------tplaLTLNE 429 Yersinia pestis 20178232 49 SSFATDEE--------ARVRL---------EAPGRDYRR----YRMEPYGGV-------------------------DVR 82 Pseudomonas aerug... 20178161 284 NFTHSIKGneleKHISAYLLPe------FTPENHPHWRYnlisRDVLQHAVAv---------------------pLQRLA 336 Pasteurella multo... 20178153 273 STATIVKDdklkPEQIIIITTntpvsgeEIKKHLELFLLpqdkPAFLGVAGKknykwqnpkeitddilkssekinFELLS 352 Rickettsia conorii 15604412 273 STATIVKDaklkPEQIIIITTntpvsgeEVKKHLELFLLpknkPHFLGVTGKknykwqspkeitddilklsekinFELLP 352 Rickettsia prowaz... 20178245 51 ASYGTDQE--------AMVRL---------EAPGREYK-----DELARYGGA-------------------------DIL 83 Ralstonia solanac... 20178234 44 -LENITLN--------VWKIS------------EEDFLK----AVFDPESFN---------------------------- 70 Thermotoga maritima 15802775 61 SSFSSSEE--------SKVRL---------EAPGRDYRR----YQMEEYGGV-------------------------DVR 94 Escherichia coli ... 20178214 277 YSPLAFQKinfyGQPDAGGTYgr----fIKGSPQLEFNNilvaESAKTNIKInp-------------------apKDISR 333 Nostoc sp. PCC 7120 16132271 31 SSFSSSEE--------AKVRL---------EAPGRDYRR----YQMEEYGGV-------------------------DVR 64 Escherichia coli K12
20178251 430 AEQEYQPifSFKFDAPSY---RTLLIEVNNSLTSVGGYKMPEKIYQI-VRVPDYPKTLRFMSQGSLLSMQGDKQISVAAR 505 Yersinia pestis 20178232 83 LYRIEQP-----LEFLKRq--KNLHRVLAEGQFKGEGLSNTLAYLWD-NWYRKSRR-VMQRAFSYESRQQVTEAVPELKM 153 Pseudomonas aerug... 20178161 337 TETTYANqqSFKLDIPEK---RCLYIEVQNKITALGGYEMKGALGDL-ACAPDYPKYVGFVGKGSILSSIGERKVTIATR 412 Pasteurella multo... 20178153 353 SVPSITTmhSFKVDTFAS---RALLVKVNQGVKTSDNLTLGSDYFQI-VQIPDNPKEVKLMSDGSILSLAGKRKLPVYSL 428 Rickettsia conorii 15604412 353 SVPKITTvhNFKVNTVAS---RTVLIKIKKGIRTSDNLTLGSDYTQI-IQIPDNPKEVKLMSDGSILSLSGEKKLPVYSL 428 Rickettsia prowaz... 20178245 84 VYRVPQP-----LDFLKAq--KNLHRIDVKANYTGEGLANTLAYLWD-NWTRQARR-AWQRVLSFATRSKAVEAAPQFSM 154 Ralstonia solanac... 20178234 71 ------------FSLLEIt----RPI-YSKKFSSEEWKEFSFPLKDRgFYFATLVS-----NEGTVFRRVIDRSLFIVTD 128 Thermotoga maritima 15802775 95 LYRIPDP-----MAFLRQq--KNLHRIVVQPQYLGDGLNNTLTWLWD-NWYGKSRR-VMQRTFSSQSRQNVTQALPELQL 165 Escherichia coli ... 20178214 334 LLQVNDEdrIIGINPYALepaKTYTITIGENLQDKFGQTLGKPVSLK-YDTGDLAGDIWVPSDLNIFPAGKDLRLNISTV 412 Nostoc sp. PCC 7120 16132271 65 LYRIPDP-----MAFLRQq--KNLHRIVVQPQYLGDGLNNTLTWLWD-NWYGKSRR-VMQRTFSSQSRQNVTQALPELQL 135 Escherichia coli K12
20178251 506 NM--TGMKLDIKRVIPSQLQHIVS--FKSSEYSSAHFNRLS------DEYFTEHFQYQTALNNdNPGEINYQGVDLSRYL 575 Yersinia pestis 20178232 154 GN--AMTAPTPYDAQPQYAPIPGLplVSQFRYPLWDAKPIE------PPQDVKLAGSSSEFIN---VVPGNVYIPLGKLK 222 Pseudomonas aerug... 20178161 413 NF--TKVKLEIGRIQEEQLRHLIA--LNQGNFQNPDLGQLK------IDNIADFFTKNYTLNNkKPQETTYLGIDLEKIV 482 Pasteurella multo... 20178153 429 GI--DKLYLEIDRINQQEVNHLISqtNRYNIFQNPTFINEYtf---nEYNISEVFQEEVIVNSqNLNLPHYTDLDFSKYF 503 Rickettsia conorii 15604412 429 GI--DKLYVEIDKIHQQEINHLISqtNRYNIFQNPTFINEYsf---nEYNISDVFQEEVIINSpNLDLPHYTNLDFGKYF 503 Rickettsia prowaz... 20178245 155 GD--QMAAPTRFSNPPQYAPLKGYelLGRFRYPIWEAKPIA------PPKDVKLEGSSSEWMP---QNVGNVMIPVGKLP 223 Ralstonia solanac... 20178234 129 -----LEAIYFSDSEKLRLHVFDSdgDFVEGAEVLLFEDS--------KLIDRVFTGKDGVVS-ITKHFDTFYIRYGDSR 194 Thermotoga maritima 15802775 166 GN--AIIKPSRYVQNNQFSPLKKYplVEQFRYPLWQAKPVE------PQQGVKLEGASSNFIS---PQPGNIYIPLGQQE 234 Escherichia coli ... 20178214 413 NLpeSKYQAAYRVVKPTDLVYFNYgnDLLPKPAEWKSFQVSgkknqsVDVTVPLREKINAKTGmLAYGVQARTNKYQENG 492 Nostoc sp. PCC 7120 16132271 136 GN--AIIKPSRYVQNNQFSPLKKYplVKQFRYPLWQAKPFE------PQQGVKLEGASSNFIS---PQPGNIYIPLGQQE 204 Escherichia coli K12
20178251 576 Ann-pSARRGVFLLTLSAWDPEKrdnqqhseEDYDedq---ewVGDSRFVVITDLGIITKQSQDRsRDVFVQSIHSGLPA 651 Yersinia pestis 20178232 223 --------PGLYLVEALVGK-----------------------YRATTVVFVSNSVAVSKVAGDE-LLVWTARKHEGTPV 270 Pseudomonas aerug... 20178161 483 Kq--aEPAMGIYWLKVTGDSDNPnstlrdtsQHMDwrndasnqFSDYRLIVISDLGVIAKKAVDGtQSVFVQSISRGEPV 560 Pasteurella multo... 20178153 504 NleeaGSYSKGLFLAKVYAKD-N--------NNII--------SQDKRLILVTDLGCIVKTDKTGtHHIFVSYISNGKPA 566 Rickettsia conorii 15604412 504 YseqaGRYSKGLFLAKVYFKDKN--------NNII--------SQDKRLILVTNLGFIVKTDKTGtHHIFVSYISNGKPA 567 Rickettsia prowaz... 20178245 224 --------AGLYIVEAVIGA-----------------------YRAHTLLFVSDTVAVTKGTSQG-MMVWTAERKSGKPV 271 Ralstonia solanac... 20178234 195 ------FFGGVYFSGGGLER------------------------EKL--FFVTDRPIYKPSDTVH-FRGQIFSFEEGLYK 241 Thermotoga maritima 15802775 235 --------PGLYLVEAMVGG-----------------------YRATTVVFVSDTVALSKVSGKE-LLVWTAGKKQGEAK 282 Escherichia coli ... 20178214 493 Ke--lWREPTTYGLVELTNLGVFs-------QWFPe-------SGLIRVNHLTDGAPVKAAVIEI-YQSKLQAKSRPEPV 555 Nostoc sp. PCC 7120 16132271 205 --------PGLYLVEAMVGG-----------------------YRATTVVFVSDTVALSKVSGKE-LLVWTAGKKQGEAK 252 Escherichia coli K12
20178251 652 ADAKVSVVAKNGVVLLSQITDSKGHVHFPAldafknERQPVMFLVEKEGDVSFLPTrATYDRNLDFSRFDIDGEETPSDp 731 Yersinia pestis 20178232 271 PDTKVLWTDGLG-VMSSGNTDADG---------------LLRLKHASPERSYVIGE-DREGGVFVSENFYYDS---EIY- 329 Pseudomonas aerug... 20178161 561 EGATVSVISRNGSIIKSDYTNEQGVVNFSSlahfkqELAPVMYLVSTQESLSFLPI-DKYDRNLDYSRFDVGGIYASENa 639 Pasteurella multo... 20178153 567 GGVKADIIGLNGEVLVSSKTDSKGHAVLSNindfskEKTPVAYILTTKDDFAFMPY-SRIDRQVNYSRFDVAGAVSSDQ- 644 Rickettsia conorii 15604412 568 EGVKVDIIGLNGEILVSSKTDSQGHTILSNihdlnkAKIPIAYVLTTRDDFSFMPY-NRVDQQVNYSRFDISGTVSSNE- 645 Rickettsia prowaz... 20178245 272 AGSAVSWTDGVG-VLASGTTQADG---------------TAELRHVAPERSYVLGV-DRAGGVFISENFYYDS---EIY- 330 Ralstonia solanac... 20178234 242 AFEKTKVTVSIFDTKKNEVYRSEFETDELG-------GFSGSMKLPDTASVGLYKVnVDHGGRRYYEYFLVEEYRKPE-- 312 Thermotoga maritima 15802775 283 PGSEILWTDGLG-VMTRGVTDDSG---------------TLQLQHISPERSYILGK-DAEGGVFVSENFFYES---EIY- 341 Escherichia coli ... 20178214 556 P-CATGKTDENGTFRVNREALQQCTAGSQN------SIKSPELLVIASEKEDWAFT--RTEEYSGVYGYGIDAGWQGNKp 626 Nostoc sp. PCC 7120 16132271 253 PGSEILWTDGLG-VMTRGVTDDSG---------------TLQLQHISPERSYILGK-DAEGGVFVSENFFYES---EIY- 311 Escherichia coli K12
20178251 732 rTLSSYLFSDRGVYRPGDRFNIGLITRTANWAT---ALDGVPLRAEIRDPRD--TLMSTLPITLDSSGFNELSYTTGENS 806 Yersinia pestis 20178232 330 -DTKIYAFTDRPLYRPGDWVSLKMVGREFKDARqsqAAASAPVRLSVIDASG--TVLQSLDLRFDAKSGANGRFQLPENA 406 Pseudomonas aerug... 20178161 640 aSLKAYLFNDRGIYRPNETLHTGIITKAQDWQL---ALNNIPLQFNLYSPSG--MLMHKQTIRLEKSGLNSVSFTLPETA 714 Pasteurella multo... 20178153 645 -GLKAYLFSDRGIYRPNEQGHIGIMLKQTDWQG---KFDGLPLEIQVTNPRG--KVIDKSKIVLDAEGFGEYLFSTLDDA 718 Rickettsia conorii 15604412 646 -GLKAYLFSDRGIYRPSEQGHIGIMLKQNDWHG---KFDGLPLEIQVTNPHG--KVIDKNKIVLNSEGLGEYLFTTFDDS 719 Rickettsia prowaz... 20178245 331 -NTKLYAFTDRPLYRPGDDVRVKFIGRNFRSATestAPAAGDIKLDVIDPTG--APVATTTTRLSGETGADARFTLPSNA 407 Ralstonia solanac... 20178234 313 --YKVEIETDKDVYISGEVVNYLVRVKYFNGQPv--AKAQVAYYVRAFPEEGsgYLVYRGTDFTDEEGNLRLGVKTEEG- 387 Thermotoga maritima 15802775 342 -NTRLYIFTDRPLYRAGDRVDVKVMGREFHDPLhssPIVSAPAKLSVLDANG--SLLQTVDVTLDARNGGQGSFRLPENA 418 Escherichia coli ... 20178214 627 -ESRGVIFSDRQLYQSGEKAWFTGFADYLQNGVi-qQDKNADYQITLVNPDG--QKTSLGTQTTNEFGTFSLEMPINKTQ 702 Nostoc sp. PCC 7120 16132271 312 -NTRLYIFTDRPLYRAGDRVDVKVIGREFHDPLhssPIVSAPAKLSVLDANG--SLLQTVNVTLDARNGGQGSFRLPENA 388 Escherichia coli K12
20178251 807 PTGEWNVYLYLVGKNnetsmLLGHTTVNVKEFEPDRLKVQLQLTPERqqgWVKPQELQANINVQNLFGTPAQERRVTSRL 886 Yersinia pestis 20178232 407 VAGGYELRFDYRG-------QTYSSAFRVAEYIKPHFEVALDLAKPD---FKTAEPVKGEIVLLYPDGKPVANARLQ--L 474 Pseudomonas aerug... 20178161 715 ETGEWFAELLVTEKNnq--tEIGSMTFQVQEFQPDNLKIKTTFNQAHaegWVAPQDLVATVQLANLFGTPAQNRKVQANL 792 Pasteurella multo... 20178153 719 LTGLYNISLYLVGDKgs-nnYLNSVSVRVGDFQPDRMKININFNNSQdelWTNPKDLKATVNLINLYGTPAENRKVSGFI 797 Rickettsia conorii 15604412 720 LTGLYNISLYL-GDQgi-nnYLNSISVRVGDFQPDRMKININFNNLKdtlWTHPKDLKATVKLINLYGIPAENRKIRGLI 797 Rickettsia prowaz... 20178245 408 QAGGYTLRFDYGG-------STYGGAFRVAEYIKPHFDVNLSLDKAG---YGTGEAIKGKISLRYPDGKPVKDGKVS--V 475 Ralstonia solanac... 20178234 388 FQGSYRLEVIVTDESq----RQIEETRSVKVYADNVLISPLDRYVST----SPGKQVRVKVKVTDLSGNPLNGLLTTSSE 459 Thermotoga maritima 15802775 419 VAGGYELRLAYRN-------QVYSSSFRVANYIKPHFEIGLALDKKE---FKTGEAVSGKLQLLYPDGEPVKNARVQ--L 486 Escherichia coli ... 20178214 703 GLGYYTIQAKGKNG------LEISGEFRVAEFKPPNFKVEVKLDKEF---AYIGDDVDINATSNYLFGAPVEGGEAKYFI 773 Nostoc sp. PCC 7120 16132271 389 VAGGYELRLAYRN-------QVYSSSFRVANYIKPHFEIGLALAKKE---FKTGEAVSGKLQLLYPDGEPVKNARVQ--L 456 Escherichia coli K12
20178251 887 ILRPMYPSFAPFPDYLFYEN--RHNSDGFETELEE---QTTDLQGMATIPLDLKSYAdATYQLQLLSEA-FEAGGGRSVA 960 Yersinia pestis 20178232 475 SLRAQQLSMVDNELQYLGQF---PVELSSTE-------LTTDGKGRAAIELPPAEKP-SRYMLTIFAS----DG------ 533 Pseudomonas aerug... 20178161 793 TLQPLLPKFSQYADYRFFDNqrNKSAILYETELNE---QVTDKEGKAHFPIDLTQYAeNTAQMLYFTADgFENDSGRAVS 869 Pasteurella multo... 20178153 798 DIRPTEFFVPRFKEYKFYSS--KGNKEFFYERLGD---ITTDSKGTANFDLNLEKYY-NATFNLTFSAEgFEPDSGRSVN 871 Rickettsia conorii 15604412 798 DIKPTEFFVTNFKEYTFYRS--KSNEEFFNEHLGD---VTTDSTGTANFDVNLEKYY-NATFNLTFSAEgFELDSGRSVT 871 Rickettsia prowaz... 20178245 476 SLRAQQVTMVEGELQYAGLF---PVKLEQQE-------LTTDGDGNAALTLPAAKEP-SRYVVTVFAN----DG------ 534 Ralstonia solanac... 20178234 460 DSTSTVAVENGEAIVTFTPK--EPKSYRIELS------FGKANTHFYVYAYCGAGTS-SEFVINPATN--TVKPGDE--- 525 Thermotoga maritima 15802775 487 SLRAQQLSMVGNDLRYAGRF---PVSLEGSE-------TVSDASGHVALNLPAADKP-SRYLLTVSAS----DG------ 545 Escherichia coli ... 20178214 774 TRQQANFIPKGWEEFTFGRQwfWPEEAPTISSDVLqsnSQLDGNDKSSQMVNVAKDLpYPMTYRVDVQ--VADVSNLSVA 851 Nostoc sp. PCC 7120 16132271 457 SLRAQQLSMVGNDLRYAGRF---PVSLEGSE-------TVSDASGHVALNLPAADKP-SRYLLTVSAS----DG------ 515 Escherichia coli K12
20178251 961 ATARVLVSPYDSLVGVKADGDLSYINRD-AVRKLNIIAVDPSLNKIALPDLSLSLIEQKYISVLTKQDSGVYKYQSRLKE 1039 Yersinia pestis 20178232 534 --AAYRVKTSKEILIERG--AARYRLS--APQRFSAAGEKVEFSYASEQPTPLK------PSSYQWIRLEDRATDSGPVA 601 Pseudomonas aerug... 20178161 870 TVKSVMVSAQPWLIGYQTKNDLAYLKRN-TPAVVNFIAVNPKLEKVAVEHLKATLLERKYVSVLTQQASGAYKYESKLIE 948 Pasteurella multo... 20178153 872 ASKSLIVSPLPYIIGFRSDSDLKYIKTK-TSAAIEFIAISNKAEKVAAPNLTLNLKKINYVNNLVADSNGNYSYSSVPIE 950 Rickettsia conorii 15604412 872 SSKSLIISPLPYIIGFRSDSNSKYIKKQ-SISTIKFIAISNKAEKVSAHNLTLKLNKINYVNNLVSDANGNYSYNTVPVE 950 Rickettsia prowaz... 20178245 535 --AAYRVKVTRELLVARG--AAPYRLS--TAANFTTPGQSVSFNLQPLPAVDGVRGASAPPAKWELVRLESRTRTEGALQ 608 Ralstonia solanac... 20178234 526 --LSVQILAPGKVMGVLGIVSNRVYDTIpVSFTGSVNLRVRIPKDIPEKNLFISFVGLDDNGRIYKLERLNVLLDTNFTT 603 Thermotoga maritima 15802775 546 --AAYRVTTTKEILIERG--LAHYSLS--TAAQYSNSGESVVFRYAALESSKQV------PVTYEWLRLEDRTSHSGDLP 613 Escherichia coli ... 20178214 852 NSQSFTALPSNRLIGLKSNFIADAGKA----FPIEVIIADPTGKLITGQRVRLELQQIKYSSVTQLVEGSQTPKNQVEYK 927 Nostoc sp. PCC 7120 16132271 516 --AAYRVTTTKEILIERG--LAHYSLS--TAAQYSNSGESVVFRYAALESSKQV------PVTYEWLRLEDRTSHSGELP 583 Escherichia coli K12
20178251 1040 QLVSEQPLQISPTG-TDFTLVTQQpGDFILVVKDSQ-GQVLNRISYTVAGNANLTRSLDr--NTELKLKLNQAEYLQGEE 1115 Yersinia pestis 20178232 602 DG-------RFALT---FERP----GTYSVELRDDK-GQLLGATGHSVSGEGVKSVPGT------VEVVFDKPEYRTGEE 660 Pseudomonas aerug... 20178161 949 NEIEQTTLQINATG-TDFTLNTGKsGDYVLVLSNEH-DQEVNRIHYAVIGNQNVSVAMDk--NTELKLRLNKKQFKPHEE 1024 Pasteurella multo... 20178153 951 TNISSDKINITANEsYIYKVPTKEaGDYVIYLTDKE-DTIFAQAEFSVIGEGNVTANLTd--KANLKVKLDKDDYTAGDT 1027 Rickettsia conorii 15604412 951 TNISSDNVNITANEgYIYNVPTKEeGDYVIYLTDTK-NRVFAQTEFSVIGEGNVTANLTd--KANLKVKLDKDDYKAGDT 1027 Rickettsia prowaz... 20178245 609 PDAKG--SATFPVK---FEQP----GSYTLSVRDAA-GNLLAASSHWVAGDGVQTVPGN------IEIVFDRDRYQIGDT 672 Ralstonia solanac... 20178234 604 MKILFDKDQYEPGEmAQITIES---NVDRVCLFLVD-EAIYAMVGAEPPVLENFLYPYM----NYPRTRGGFPHYWRLYV 675 Thermotoga maritima 15802775 614 SGGK-----SFTVN---FDKP----GNYNLTLRDKD-GLILAGLSHAVSGKGSMSHTGT------VDIVADKTLYQPGET 674 Escherichia coli ... 20178214 928 TVAQTEITSTSNPQsVNLTPPES--GTYRIRVNFSDaKNELGATDSQIWVTGGNAVFWGtrdKDVLEVKLDKKEYKAGET 1005 Nostoc sp. PCC 7120 16132271 584 SGGK-----SFTVN---FAKP----GNYNLTLRDKD-GLILAGLSHAVSGKGSTAHTGT------VDIVADKTLYQPGET 644 Escherichia coli K12
20178251 1116 IEIAINAPYAG--SGLITIEKDKVYSWQWFHSDTTSSVQRIRIPPAME-GNGYINVQFVRDVNSDEIFMSPLS----YGV 1188 Yersinia pestis 20178232 661 ASALITFPEPVe-DALLSLERDKVEATALLSKGADWLRLEKLNPTQYR-VWIPVREEFSPNLTFSVLYTKGGD----YSF 734 Pseudomonas aerug... 20178161 1025 IEIAIHAPYAG--TGLITIESDRVYAHKWFKATTNSSVQRIQLPENFE-GTGYVNVQFSRDIHSDDIFTSPLS----YGV 1097 Pasteurella multo... 20178153 1028 ILLNIITPYTG--YGLITIETDKVHNFEWFKADENNSIQEIKIPDGFE-GKGYVNVQFIRDIEATEIFISPFS----YAV 1100 Rickettsia conorii 15604412 1028 ILLNIKTPYTG--HGLITIETDKVHNFKWFKTDKNNSIQAIKILTVLK-VKDT--------------------------- 1077 Rickettsia prowaz... 20178245 673 AEALITFPQPVd-DALLTLERDKVERHALLSGGGDWLALQRVTPSQYR-ARIKIGAEFSPNMTFSALTVRDGD----MVF 746 Ralstonia solanac... 20178234 676 SRNSFRNKLASlpEEKTFADFKQNALPSKLNVREYFPDTALWIPSLKL-HNGTARVSFKVPDSITSFRATA------YGF 748 Thermotoga maritima 15802775 675 AKMLITFPEPId-EALLTLERDRVEQQSLLSHPANWLTLQRLNDTQYE-ARVPVSNSFAPNITFSVLYTRNGQ----YSF 748 Escherichia coli ... 20178214 1006 ATALIQSPYADa-ELYFAVIKDKPIYQQITKVQGSAPQIQFRVTPEMLpNAAVEAVLVRQGKPINQVEVGSLDnlvkIGF 1084 Nostoc sp. PCC 7120 16132271 645 AKMLITFPEPId-EALLTLERDRVEQQSLLSHPANWLTLQRLNDTQYE-ARVPVSNSFAPNITFSVLYTRNGQ----YSF 718 Escherichia coli K12
20178251 1189 MPFKISTKARQAAIELASPSVIK-PGEVLPIKVTTDS-------PQRVVVFAVDEGILQVARYRLKDPLDYFFRKRELSV 1260 Yersinia pestis 20178232 735 QNAGIKVGMPQVEIDIATDKERYePGETVTVTLATRFagk--pvSSHLTVSVVDEMVYALQAEIAPGIDQFFYHPRRNNV 812 Pseudomonas aerug... 20178161 1098 VPFTVNVDNRRLKLQLDSPKKVK-SGETVEFKLSSDK-------PSKALIYAVNEGILQVAGYQFTDPLSYFFPKYALQV 1169 Pasteurella multo... 20178153 1101 VPFTAGIYKHKQDIGLTLPAKIK-SGEKLAIRYRTTN-------PGKIIIFAVDAGILSFAGYQTPDPLNYFINDKALEV 1172 Rickettsia conorii 15604412 -------------------------------------------------------------------------------- Rickettsia prowaz... 20178245 747 QNAGIVVTQPALDLTVRADKAVYaPGETVTLDLSSALagk--pvPANLTVSVVDEMVYVLQPEVAPSIVDFFYHPRRNSV 824 Ralstonia solanac... 20178234 749 SKDRFSQTESEMVVSKKFYLMPHlPSFLRESDVIKISatvfnrtSKTLPVQLTVELPENIELLEGSSSRHFLMEANSSHT 828 Thermotoga maritima 15802775 749 QNAGIKVAVPQLDIRVKTDKTHYqPGELVNVELTSSLkgk--pvSAQLTVXVVDEMIYALQPEIAPNIGKFFYPLGRNNV 826 Escherichia coli ... 20178214 1085 TPFKVNLEDKYLKLQVKPAQASLePGAEETIQLEVKDnqg-nptKGQLTVMVVNEAVLQLSGYRPPNLVDTVYAEQPIST 1163 Nostoc sp. PCC 7120 16132271 719 QNAGIKVAVPQLDIRVKTDKTHYqPGELVNVELTSSLkgk--pvSAQLTVGVVDEMIYALQPEIAPNIGKFFYPLGRNNV 796 Escherichia coli K12
20178251 1261 QSAQILDLILPEFsKLMALTSAPGGDAGe-------GLDLHLNPFKRKqDKPVAYWSGITEVN--GETTFNYPIPdYFNG 1331 Yersinia pestis 20178232 813 RTSASLAFISYDV-ALPGSTSAPGRANrs------eRGVKVLERPRRE-DVDTAAWQPELVTDaqGKASFSFRMP-DSLT 883 Pseudomonas aerug... 20178161 1170 QTAQILDLILPEF-SKVMQFAQTGGDADmnmelamkMAMANMNPFKRKtDKPVAYWSGIVDIH--GEKTVSYQIPeEFNG 1246 Pasteurella multo... 20178153 1173 RTSQIMDLILPER-PLLMKAYMAAPAGDgc-----iNVARNLNPFKRK-SQPPIAFWSGILEAdlDEREVTFDIPsYFNG 1245 Rickettsia conorii 15604412 -------------------------------------------------------------------------------- Rickettsia prowaz... 20178245 825 RTTSSQSFISYDL-ALSSLPGKPGGTYGrh----neRGVKVLERPRRD-EQDTAAWVANLQTGadGRARMTFTMP-DSLA 897 Ralstonia solanac... 20178234 829 ETWTVKAVSASEG--SFVKFVAVGEDLN---------DAVSMRLPVER-FAFEREFYRIMLLD--GKETLEIPGQ-FISS 893 Thermotoga maritima 15802775 827 RTSSSLSFISYDQ-ALSSEPVAPGATNrs------eRRVKMLERPRRE-EVDTAAWMPSLTTDkqGKAYFTFLMP-DSLT 897 Escherichia coli ... 20178214 1164 RFTDNRPDVILQP-QDVAKPKGWGYGGG--------FSTGAANTRTRTdFQPLAYYNGSVLTDasGNAQITVKLP-DDLT 1233 Nostoc sp. PCC 7120 16132271 797 RTSSSLSFISYDQ-ALSSEPVAPGATNrs------eRRVKMLERPRRE-EVDTAAWMPSLTTDkqGKAYFTFLMP-DSLT 867 Escherichia coli K12
20178251 1332 KIRVMAISAT-----PDRIGKVQTSTTVRDNFILTPNVPAMVAPGDEFDVTVGVSNnlqgLKGKAVDitVrLTPPPQLEV 1406 Yersinia pestis 20178232 884 RWRITARAIDd----NGQVGQKKQFLRSEKPLYLKWSGPTRFRQGDQPDLGLFVFN----QGEQP------VKAELLSGP 949 Pseudomonas aerug... 20178161 1247 NLKVMAIALSh---dGKHLGHVATETLVRNDLILSPTVPLTLTPGDESEINVVIAN----NTNKAQRvnLkATLEPQLSF 1319 Pasteurella multo... 20178153 1246 TLRVIGVASS-----LDSIGTSKADLLVQSDLIINPNLPLFVAPNDEFTVPVTIFN----NLKDSGNaqVfLNIETSEGL 1316 Rickettsia conorii 15604412 -------------------------------------------------------------------------------- Rickettsia prowaz... 20178245 898 RWRVTVRAVSttgaaDGIVGQRTASIRSDKALYLKWTGPSRFRESDQPRLDMVAFN----QTDKD------ITADWIVSG 967 Ralstonia solanac... 20178234 894 RIRFLDSIVP-------LVEDSLKRLIDFPYGCVEQTMSRFFPAVVAASAGIEVEN----LEEIIQR--G-LFKLYSYQH 959 Thermotoga maritima 15802775 898 RWRITARGMNg----DGLVGQGRAYLRSEKNLYMKWSMPTVYRVGDKPSAGLFIFS----QQDN-------EPVALVTKF 962 Escherichia coli ... 20178214 1234 TWRVMAVATDg----NLRFGNGDATFITTKPLLSNAILPQFVRPGDRILAGLSVTN----NTGNTGNlsInGEISGAVKF 1305 Nostoc sp. PCC 7120 16132271 868 RWRITARGMNg----DGLVGQGRAYLRSEKNLYMKWSMPTVYRVGDKPAAGLFIFS----QQDN-------EPVALVTKF 932 Escherichia coli K12
20178251 1407 VGE--AQHSLSLAEKRETLVSFRLRAR----SALGDAPLVFDASYGSQSSRRTVst---sVRPAMPFRTQSVMGRMEG-- 1475 Yersinia pestis 20178232 950 PGSq-RSQTLELAKG-VNYIPLAQQpl---sDGDWSAELRQDGQVRDRLAVRFN------LLADGWQVEQMQNLSLA--- 1015 Pseudomonas aerug... 20178161 1320 IGE--AEKVIDIAPMSESRADFVIKATqelgSSTIRFIASYEDAQQQKVDAVRHvt--lsVRPIMPKQFATQIQKVAAg- 1394 Pasteurella multo... 20178153 1317 KILd-YPKEIPIDENKEATINVKLKATdqlgSADLKVVASINHLKPDIISMAVVhsseltSTTSVRPASPSVTTVNTGfi 1395 Rickettsia conorii 15604412 -------------------------------------------------------------------------------- Rickettsia prowaz... 20178245 968 AGLn-INQRVTLKRG-ANYLHAPLSGTpalqAGIVNAELKQDDRVSDRLQTTVK------LDATGWLADRESIVPLTQ-- 1037 Ralstonia solanac... 20178234 960 NDG--GWGWFRFGESDDFMTCYVMEGLyftmKAGYDVAESVLQRGIEYLRKHPSa-----YGSYVLDLYGVNHEPFKP-- 1030 Thermotoga maritima 15802775 963 AGAe-MRQTLTLHKG-ANYISLAQNiq---qSGLLSAELQQNGQVQDSISTKLS------FVDNSWPVEQQKNVMLG--- 1028 Escherichia coli ... 20178214 1306 NSKnpTTTTLQTQAESATQAYRFPMVAdsvgVGKVRFTTQLNG-TADAFELPLQ------VKPLEITEQIVETGVSQKq- 1377 Nostoc sp. PCC 7120 16132271 933 AGAe-MRQTLTLHKG-ANYISLTQNiq---qSGLLSAELQQNGQVQDSISTKLS------FVDNSWPVEQQKNVMLG--- 998 Escherichia coli K12
20178251 1476 --NKHTVTNLRQMFDNYAQRQATASHSPLVLTQG-LARYLADYPYYSSEQIVSRSIPLIMQSKHPEMDs----------- 1541 Yersinia pestis 20178232 1016 -----AASNPLQLPADARDVRLRLADGPAAAYLG-NLDDLLEYPYGGVEQTASQLLPLSIAYPALAGg-----------e 1078 Pseudomonas aerug... 20178161 1395 --KTVTSPLPMTLFPQHRQQSALFSAAPLALAQG-VSTYLTHYDNYCTEQMISAAMPMVLFSKNPAYQplltalsrkapq 1471 Pasteurella multo... 20178153 1396 tdNKANLKILRDVYPEFAKLQISASKSPLAIISG-FKDFLDNYPYGCTEQLISQNFANILLYNEQELVqi---------l 1465 Rickettsia conorii 15604412 -------------------------------------------------------------------------------- Rickettsia prowaz... 20178245 1038 ---LQGTRLPLGLPADARDVRLRVVGNTASQFAR-VADDLIEYPYGCAEQTASRLIPLALAQQSLAATgarl----pdgn 1109 Ralstonia solanac... 20178234 1031 ----ESEADLVFLSLSSKEALKQLMNYVVQDEQKaYLNVYSNNPLISEIQLNSVFLRALAKWKEFPELe----------- 1095 Thermotoga maritima 15802775 1029 -----GGDNALMLPEQASNIRLQSSETPQEIFRN-NLDALVDEPWGGVINTGSRLIPLSLAWRSLADh-----------q 1091 Escherichia coli ... 20178214 1378 --IKIPLNVDKNTFPEAGGLDIQLASTLIPEIKApAKQVLTDNDLPFTEPSASQLIIATNLQTIAQKYg----------q 1445 Nostoc sp. PCC 7120 16132271 999 -----GGDNALMLPEQASNIRLQSSETPQEIFRN-NLDALVDEPWGGVINTGSRLIPLSLAWRSLADh-----------q 1061 Escherichia coli K12
20178251 1542 ALNQNEVRDQLKNMLRILSS-RQNSTGAIGLWHAS-PTPDPFVTPYVVQFLLEA-KSAGYSLPNDILEGA--NN-ALRLL 1615 Yersinia pestis 20178232 1079 PRIRDRLRLIMQNSRLRLVQ-MAGPDAWFAWWGGD-VDGDAFLTAYAYYADWYAsRALEIQLPAEHWQRI--LEpYAKQA 1154 Pseudomonas aerug... 20178161 1472 NVGSTGTHDTLEKAFKLLPS-RQTEYGNYGIWNNv-EEGNLFVTAYVAHFLIEA-RERHLVLPKAWFGQHglFNnTISAL 1548 Pasteurella multo... 20178153 1466 KTDRKNMDESLSKIFQTLSE-RQNYDGGFRYWNNFnDDSDPFISVYAMHFLSEG-ATRYLAVPSDTFNQG---IyYLENM 1540 Rickettsia conorii 15604412 -------------------------------------------------------------------------------- Rickettsia prowaz... 20178245 1110 PAGTQGVDALLRTQRQRLAL-LAGTNGTFGWWGEL-TSSSALITSYAYYADWLAsRAVGISLPADNWKQV--LEaYKRTS 1185 Ralstonia solanac... 20178234 1096 RKVTNYLLLKKDSAFWTSTKdTSFVILALLEAMPEyASTTLKVINSENTFELKPgEERSLVPGSLTVSGKgiVEvEVVYI 1175 Thermotoga maritima 15802775 1092 SAAANDIRQMIQDNRLRLMQ-LAGPGARFTWWGED-GNGDAFLTAWAWYADWQAsQALGVTQQPEYWQHM--LDsYAEQA 1167 Escherichia coli ... 20178214 1446 TFAEFNSRQQANLAVEKLQK-LQISDGGFAAFPGQ-EKSDPWVSAYSVESLVKAsQVFPNLVDTGMLSRL--KTyLQKVL 1521 Nostoc sp. PCC 7120 16132271 1062 SAAANDIRQMIQDNRLRLMQ-LAGPGARFTWWGED-GNGDAFLTAWAWYADWQAsQAIGVTQQPEYWQHM--LDsYAEQA 1137 Escherichia coli K12
20178251 1616 AAR---------PYDDL-YSLRLRAFAVYLLTLQGEIT----TNTLASVQSTLQQl-YPDSWQTDLSAIYLASSYRLLKM 1680 Yersinia pestis 20178232 1155 TQTpllqralilAFARD-MQLPVNTLLGGLLNDLANAGe---GQARAEPLEADDGl-VLGDPDSAVGLAAARVLAVDLAR 1229 Pseudomonas aerug... 20178161 1549 EEQsv------pQEGDSlATLRQRAYSAYLLTRLAKVP----SNALLSIRTQLEQqfSAEEWQKDTVSAWLAAAYHMLKQ 1618 Pasteurella multo... 20178153 1541 ANr--------sINSL--DEAREKAYAVYILTQNSVIT----TSYIANILKYLDEy-HKNTWQDDLTSVYLAASYKMLQM 1605 Rickettsia conorii 15604412 -------------------------------------------------------------------------------- Rickettsia prowaz... 20178245 1186 QNEpllhralalWFANE-MGLPVATPLSGVAAELARNAk---APADAEPAPG-DSl-IFVAPDSPRGRQVAAILTAQLMR 1259 Ralstonia solanac... 20178234 1176 EVPk-------eAVSEG-LEIKREFYKRYELLIEENKMi--vDAFVPIGRGYVPR--SIHPVEKEQTEELYILPYKYWKK 1243 Thermotoga maritima 15802775 1168 DNMpllhralvlAWAQE-MNLPCKTLLKGLDEAIARRGtkteDFSEEDTRDINDSl-ILDTPESPLADAVANVLTMTLLK 1245 Escherichia coli ... 20178214 1522 ANPg--------EYDFCkQQLCKRQLQLNALIALSELG----DKRNTFLTDIYEQr-NNFDLVTQIKLARYLSQFPEWQD 1588 Nostoc sp. PCC 7120 16132271 1138 DNMpllhralvlAWAQE-MNLPCKTLLKGLDEAIARRGtkteDFSEEDTRDINDSl-ILDTPESPLADAVANVLTMTLLK 1215 Escherichia coli K12
20178251 1681 DDEANK---LLQPTWKQLGKAYSKAWWTQNYFDPLVQDATRLYLITRHfpEKVSSIPPQALENMVLALRDEH----YTTY 1753 Yersinia pestis 20178232 1230 QLRVAVpapLAAQAETATQRLREAGLPFTDALLASRSAVDGQQASALL--QRLAPAQSTLERALALTWLQGA----LAQA 1303 Pseudomonas aerug... 20178161 1619 DNEANK---LIEPVINQLVAARPAQWTYDAYSDPLIKDSTMLYVIARHfpAQLSKVSDSVLERIVQDLNQQR----YNTL 1691 Pasteurella multo... 20178153 1606 NEEAEKl--LDRFTLNKPISKTDYQYYNPLIKYSQYLYLIAMHFPERL--KDFDPKIVQDIALFAKDNYNSL----SASY 1677 Rickettsia conorii 15604412 -------------------------------------------------------------------------------- Rickettsia prowaz... 20178245 1260 QVGQPVpeaLVSADIAARTALANDTSPLVQSLLLMGGGRSAADPAPLL--ARASAAMPTMDRAVALVWLQKG----LGGL 1333 Ralstonia solanac... 20178234 1244 TIEYRG-----VPLEINGAEVKIKGETYTFFRIETFNGLILVFFRNEAliYDTEKNTITRYLDVTDAGFMRS-----GPV 1313 Thermotoga maritima 15802775 1246 KAQLKSt-vMPQVQQYAWDKAVNSNQPLAHTVVLLNSGGDATQAAAIL--SGLTAEQSTIERALAMNWLAKY----MATM 1318 Escherichia coli ... 20178214 1589 ESQQLVnklQQNISETGRTAVVSLPPSWGWMSSPTTAQAQALRLFIAK--QSKPEIIDKLLQSLLALRRDGTwqtdYNNA 1666 Nostoc sp. PCC 7120 16132271 1216 KAQLKSt-vMPQVQQYAWDKAANSNQPLAHTVVLLNSGGDATQTAAIL--SGLTAEQSTIERALAMNWLAKY----MATM 1288 Escherichia coli K12
20178251 1754 SSAMSILALESYTSq-vAAQQDTPETLQIIEISKSKGIDPNVISTLNGLFVqgdftgeakaiqFNNYASAPAWYVVNQSG 1832 Yersinia pestis 20178232 1304 P---QGKLPQP------PKDWQAQRGASGETYWQWRGRGIPSWVDLDEAPAr-----------PLPVALSYRSAQAPSGQ 1363 Pseudomonas aerug... 20178161 1692 SSSMVLLALDAYAQqhqSELANLQIQHQGKEISQSTPLFRFADLADTQMDIs-----------FVNNSQQPAWFALSQVG 1760 Pasteurella multo... 20178153 1678 AIMASLAYADKINHv-dEATIKVTSTDKEVTLKGNKVMIAELSVENKNIDL------------TSSSNGFFYQLLTSGYD 1744 Rickettsia conorii 15604412 -------------------------------------------------------------------------------- Rickettsia prowaz... 20178245 1334 QG-ANVAAIQPVLS---AGGWQAARSTVGVPTWRWAGAQPPAALDLASTPSdv---------tTQSAIVSYRSRAPEASR 1400 Ralstonia solanac... 20178234 1314 FLMKGFVLVGD-------EKIPVPEDVTGLSCTMDEILLRGENKTYWYRNGe-----------FVDLPFVARRVFFWDGK 1375 Thermotoga maritima 15802775 1319 P---SVVLPAP------AGAWAKHKLTGGGEYWRWVGQGVPDILSFGDELS------------PQNVQVRWREAAKTAQQ 1377 Escherichia coli ... 20178214 1667 QALTALVEYGQLQPt--PPNFVATVQLAGRKLGENRFTGYKNPSLQLSVPMnqlp----rgrhDLTLQKSGNGTLHYLVA 1740 Nostoc sp. PCC 7120 16132271 1289 P---PVVLPAP------AGAWAKHKLTGGGEDWRWVGQGVPDILSFGDELS------------PQNVQVRXREPAKMAQQ 1347 Escherichia coli K12
20178251 1833 --YDLQPPKDAIsNGLEISRS--------------------YTDEQGKPVT---QVTLGQKVNVHLKIRaNAKQGQnNLA 1887 Yersinia pestis 20178232 1364 --LPVQISRRLL-RLVPGEGA---------------------FEFKVEEVGd-kPLSSDELYLDEVTLNvPEDTALrYGM 1418 Pseudomonas aerug... 20178161 1761 --YPQNAAQQALsQGLEVDRS--------------------YTDKEGKPIR---QVKIGDVIYVTVKIR-ASTDYVsDVI 1814 Pasteurella multo... 20178153 1745 --KQLTENKEIV-KGIEITKK--------------------YLDENNKEVSk-vKLGDNITVEITMRSG-SNKTLS-NMV 1798 Rickettsia conorii 15604412 -------------------------------------------------------------------------------- Rickettsia prowaz... 20178245 1401 --LPITVERKLY-RLEPVDAAapkddakapkraaadvtanaGITFKAKPVKpgdTLDSNALYVDEVVLT-PRQGTYrYGL 1476 Ralstonia solanac... 20178234 1376 --KLVAENIRFS-GSSKTLRN--------------------RVFEVVFDVGd-vKIELGDIIKTVVRVK---GDGN-YLI 1427 Thermotoga maritima 15802775 1378 snIPVTVERQLY-RLIPGEEE---------------------MSFTLQPVTs-nEIDSDALYLDEITLTsEQDAVLrYGQ 1434 Escherichia coli ... 20178214 1741 ynYRLQGNQPGRfNGLRITREisqvn-----------akriLRKTGIYALDqplTLALGQVFDIGLEIIvDRPVDH--LV 1807 Nostoc sp. PCC 7120 16132271 1348 snIPVTVERQLY-RLIPGEEE---------------------MSFILQPVTs-nEIDSDALYLDEITLTsEQDAVLrYGQ 1404 Escherichia coli K12
20178251 1888 IVDLLPGGFEVVQQTAPEPEFydnqdDQDeeTGSGWQSPLMVSgsswypdYSDIREDRVIIYGS-ASTDVKEFIYQIKST 1966 Yersinia pestis 20178232 1419 LELPLPPGADVERTTWGIKIS------GLagDEATTLERARNE-------PGELFYGVPVDSLS----GEQRFRHLVRFS 1481 Pseudomonas aerug... 20178161 1815 ITDLYPAGFEVLWQQGAE---------D------DFEDSWLAQ-------HTELREDRLLSYLD-AEKEMKVLKYQLKAV 1871 Pasteurella multo... 20178153 1799 LIDLLPAGFELLPDNNHINILe----------rTQEVMIWKPI-------YINNRDDRVMIFGT-ISDQKMTYQYKIKAV 1860 Rickettsia conorii 15604412 -------------------------------------------------------------------------------- Rickettsia prowaz... 20178245 1477 VEVPLPPGAEVEATTWGIQIDglkgePNEgnGPQPFERRAAYE-------MGQLSYNQPVPTLE----RPTALRQLVRFS 1545 Ralstonia solanac... 20178234 1428 VEDFIPSCAQVLSNYREKGIE-----ENK--FSYSWYSSWNAWy-----sGREIRTDRVALFAR--YLYGNSFDYVWRAT 1493 Thermotoga maritima 15802775 1435 VEVPLPPGADVERTTWGISVNk----PNAgkQQGQLLEKARNE-------MGELAYMVPVKELT----GTVTFRHLLRFS 1499 Escherichia coli ... 20178214 1808 IKDPLPAGLEAVDASFQTTT-------A---ALQAKADSWELG-------FRNIYSDRIIAYADhLEPGVYSLHYLVRSV 1870 Nostoc sp. PCC 7120 16132271 1405 VEVPLPPGADVERTTWGISVNk----PNAakQQGQLLEKARNE-------MGELAYMVPVKELT----GTVTFRHLLRFS 1469 Escherichia coli K12
20178251 1967 NTGRFVVPPAYGEAMYDRNVQALSv------GKGHILVVPP 2001 Yersinia pestis 20178232 1482 QKGSFNLPPARYLRLYAPEQQALE-------AKPALAKVKV 1515 Pseudomonas aeruginosa 20178161 1872 NIGTFQIPPIYAESMYDRAIKAYSa------SEGQIKVRK- 1905 Pasteurella multocida 20178153 1861 NKGIFSTPAIYSEAMYDPQTYYRG-------VIGNIIVE-- 1892 Rickettsia conorii 15604412 ----------------------------------------- Rickettsia prowazekii 20178245 1546 LPGRFALPPARYFRMYQPEAKALQ-------GDGKAASYPF 1579 Ralstonia solanacearum 20178234 1494 AEGVFHLLPARVYPMYSRGLYAHTdpdvlfiGADFIDGRDD 1534 Thermotoga maritima 15802775 1500 QKGQFVLPPARYVRSYAPAQQSVA-------AGSEWTGMQV 1533 Escherichia coli O157:H7 EDL933 20178214 1871 TPGTFSWPGAEVHLQYAPEEFGRT-------AEMKLIVEEK 1904 Nostoc sp. PCC 7120 16132271 1470 QKGQFVLPPARYVRSYAPAQQSVA-------AGSEWTGMQV 1503 Escherichia coli K12
Jiyao W et al.(2023). "The conserved domain database in 2023.",