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lama2 laminin, alpha 2 [ Perca flavescens (yellow perch) ]

Gene ID: 114572804, updated on 15-Mar-2024

Summary

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Gene symbol
lama2
Gene description
laminin, alpha 2
Locus tag
EPR50_G00190060
Gene type
protein coding
RefSeq status
MODEL
Organism
Perca flavescens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Perciformes; Percoidei; Percidae; Percinae; Perca
Orthologs
human zebrafish all
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Genomic context

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See lama2 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
74
Annotation release Status Assembly Chr Location
100 current PFLA_1.0 (GCF_004354835.1) 18 NC_041348.1 (23268070..23460471)

Chromosome 18 - NC_041348.1Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase receptor type K Neighboring gene vesicular inhibitory amino acid transporter-like Neighboring gene regulator of G protein signaling 6 Neighboring gene signal-induced proliferation-associated 1 like 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_041348.1 Chromosome 18 Reference PFLA_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of embryonic development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
laminin subunit alpha-2
Names
laminin subunit alpha 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Perca flavescens Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PFLA_1.0 Primary Assembly

Genomic

  1. NC_041348.1 Reference PFLA_1.0 Primary Assembly

    Range
    23268070..23460471
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028604575.1 → XP_028460376.1  laminin subunit alpha-2 isoform X1

    UniProtKB/TrEMBL
    A0A484CF35
    Conserved Domains (10) summary
    smart00180
    Location:950 → 994
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:847 → 899
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2984 → 3135
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR02168
    Location:1694 → 1984
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06009
    Location:2033 → 2154
    Laminin_II; Laminin Domain II
    pfam06008
    Location:1580 → 1833
    Laminin_I; Laminin Domain I
    pfam00052
    Location:1216 → 1354
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1089 → 1146
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2821 → 2948
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:34 → 270
    Laminin_N; Laminin N-terminal (Domain VI)

  2. XM_028604576.1 → XP_028460377.1  laminin subunit alpha-2 isoform X2

    UniProtKB/TrEMBL
    A0A484CF35
    Conserved Domains (10) summary
    smart00180
    Location:950 → 994
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:847 → 899
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2982 → 3133
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR02168
    Location:1694 → 1984
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06009
    Location:2033 → 2152
    Laminin_II; Laminin Domain II
    pfam06008
    Location:1580 → 1833
    Laminin_I; Laminin Domain I
    pfam00052
    Location:1216 → 1354
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1089 → 1146
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2819 → 2946
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:34 → 270
    Laminin_N; Laminin N-terminal (Domain VI)

  3. XM_028604577.1 → XP_028460378.1  laminin subunit alpha-2 isoform X3

    UniProtKB/TrEMBL
    A0A484CF35
    Conserved Domains (10) summary
    smart00180
    Location:950 → 994
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:847 → 899
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2936 → 3087
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR02168
    Location:1648 → 1938
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06009
    Location:1987 → 2106
    Laminin_II; Laminin Domain II
    pfam06008
    Location:1534 → 1787
    Laminin_I; Laminin Domain I
    pfam00052
    Location:1216 → 1354
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1089 → 1146
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2773 → 2900
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:34 → 270
    Laminin_N; Laminin N-terminal (Domain VI)

  4. XM_028604578.1 → XP_028460379.1  laminin subunit alpha-2 isoform X4

    UniProtKB/TrEMBL
    A0A484CF35
    Conserved Domains (9) summary
    smart00180
    Location:636 → 680
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:442 → 494
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2670 → 2821
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR02168
    Location:1380 → 1670
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06009
    Location:1719 → 1840
    Laminin_II; Laminin Domain II
    pfam06008
    Location:1266 → 1519
    Laminin_I; Laminin Domain I
    pfam00052
    Location:902 → 1040
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:775 → 832
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2507 → 2634
    Laminin_G_1; Laminin G domain
Nucleotide Protein
Heading Accession and Version

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