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CD74 CD74 molecule [ Pseudonaja textilis ]

Gene ID: 113433814, updated on 15-Mar-2024

Summary

Gene symbol
CD74
Gene description
CD74 molecule
See related
Ensembl:ENSPTXG00000013677
Gene type
protein coding
RefSeq status
MODEL
Organism
Pseudonaja textilis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Elapidae; Acanthophiinae; Pseudonaja
Orthologs
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Genomic context

See CD74 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
100 current EBS10Xv2-PRI (GCF_900518735.1) Unplaced Scaffold NW_020769314.1 (27967343..27986801, complement)

NW_020769314.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC113433517 Neighboring gene treacle ribosome biogenesis factor 1 Neighboring gene ribosomal protein S14 Neighboring gene N-deacetylase and N-sulfotransferase 1

Genomic regions, transcripts, and products

Genomic Sequence:
NW_020769314 Unplaced Scaffold Reference EBS10Xv2-PRI

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables MHC class II protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables macrophage migration inhibitory factor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in T cell activation involved in immune response IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in antigen processing and presentation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in negative regulation of DNA damage response, signal transduction by p53 class mediator IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of macrophage cytokine production IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of peptidyl-tyrosine phosphorylation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of type 2 immune response IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein trimerization IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
HLA class II histocompatibility antigen gamma chain

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pseudonaja textilis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EBS10Xv2-PRI

Genomic

  1. NW_020769314.1 Reference EBS10Xv2-PRI

    Range
    27967343..27986801 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_026696608.1XP_026552393.1  HLA class II histocompatibility antigen gamma chain

    UniProtKB/TrEMBL
    A0A670ZD18
    Related
    ENSPTXP00000019763.1, ENSPTXT00000020364.1
    Conserved Domains (3) summary
    cd00191
    Location:180238
    TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
    pfam08831
    Location:110178
    MHCassoc_trimer; Class II MHC-associated invariant chain trimerisation domain
    pfam09307
    Location:1894
    MHC2-interact; CLIP, MHC2 interacting