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lama2 laminin, alpha 2 [ Cyprinodon variegatus (sheepshead minnow) ]

Gene ID: 107080976, updated on 14-Mar-2024

Summary

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Gene symbol
lama2
Gene description
laminin, alpha 2
See related
Ensembl:ENSCVAG00000000081
Gene type
protein coding
RefSeq status
MODEL
Organism
Cyprinodon variegatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae; Cyprinodon
Orthologs
human zebrafish all
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Genomic context

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See lama2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
75
Annotation release Status Assembly Chr Location
100 current C_variegatus-1.0 (GCF_000732505.1) Unplaced Scaffold NW_015150490.1 (1779936..2004025)

NW_015150490.1Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase receptor type K Neighboring gene vesicular inhibitory amino acid transporter-like Neighboring gene regulator of G-protein signaling 6-like Neighboring gene signal-induced proliferation-associated 1 like 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_015150490.1 Unplaced Scaffold Reference C_variegatus-1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of embryonic development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
laminin subunit alpha-2
Names
laminin subunit alpha 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cyprinodon variegatus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference C_variegatus-1.0 Primary Assembly

Genomic

  1. NW_015150490.1 Reference C_variegatus-1.0 Primary Assembly

    Range
    1779936..2004025
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015369189.1 → XP_015224675.1  laminin subunit alpha-2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q2C9Y8
    Conserved Domains (13) summary
    smart00180
    Location:1045 → 1089
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1306 → 1435
    LamB; Laminin B domain
    smart00282
    Location:2246 → 2388
    LamG; Laminin G domain
    cd00055
    Location:903 → 944
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3082 → 3233
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR04527
    Location:1902 → 2012
    mycoplas_twoTM; two transmembrane protein
    pfam00052
    Location:569 → 698
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1497 → 1543
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2920 → 3047
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:39 → 274
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06008
    Location:1675 → 1928
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2128 → 2249
    Laminin_II; Laminin Domain II
    cl21509
    Location:1839 → 1932
    ApoLp-III_like; Apolipophorin-III and similar insect proteins

  2. XM_015369209.1 → XP_015224695.1  laminin subunit alpha-2 isoform X4

    UniProtKB/TrEMBL
    A0A3Q2C9Y8
    Conserved Domains (13) summary
    smart00180
    Location:1045 → 1089
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1306 → 1435
    LamB; Laminin B domain
    smart00282
    Location:2246 → 2388
    LamG; Laminin G domain
    cd00055
    Location:903 → 944
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3051 → 3202
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR04527
    Location:1902 → 2012
    mycoplas_twoTM; two transmembrane protein
    pfam00052
    Location:569 → 698
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1497 → 1543
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2889 → 3016
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:39 → 274
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06008
    Location:1675 → 1928
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2128 → 2249
    Laminin_II; Laminin Domain II
    cl21509
    Location:1839 → 1932
    ApoLp-III_like; Apolipophorin-III and similar insect proteins

  3. XM_015369194.1 → XP_015224680.1  laminin subunit alpha-2 isoform X2

    UniProtKB/TrEMBL
    A0A3Q2C9Y8
    Conserved Domains (13) summary
    smart00180
    Location:1045 → 1089
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1306 → 1435
    LamB; Laminin B domain
    smart00282
    Location:2244 → 2386
    LamG; Laminin G domain
    cd00055
    Location:903 → 944
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3080 → 3231
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR04527
    Location:1902 → 2012
    mycoplas_twoTM; two transmembrane protein
    pfam00052
    Location:569 → 698
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1497 → 1543
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2918 → 3045
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:39 → 274
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06008
    Location:1675 → 1928
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2128 → 2247
    Laminin_II; Laminin Domain II
    cl21509
    Location:1839 → 1932
    ApoLp-III_like; Apolipophorin-III and similar insect proteins

  4. XM_015369215.1 → XP_015224701.1  laminin subunit alpha-2 isoform X5

    UniProtKB/TrEMBL
    A0A3Q2C9Y8
    Conserved Domains (13) summary
    smart00180
    Location:1045 → 1089
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1306 → 1435
    LamB; Laminin B domain
    smart00282
    Location:2200 → 2342
    LamG; Laminin G domain
    cd00055
    Location:903 → 944
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3036 → 3187
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR04527
    Location:1856 → 1966
    mycoplas_twoTM; two transmembrane protein
    pfam00052
    Location:569 → 698
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1497 → 1543
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2874 → 3001
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:39 → 274
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06008
    Location:1629 → 1882
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2082 → 2203
    Laminin_II; Laminin Domain II
    cl21509
    Location:1793 → 1886
    ApoLp-III_like; Apolipophorin-III and similar insect proteins

  5. XM_015369202.1 → XP_015224688.1  laminin subunit alpha-2 isoform X3

    UniProtKB/TrEMBL
    A0A3Q2C9Y8
    Conserved Domains (13) summary
    smart00180
    Location:1045 → 1089
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1306 → 1435
    LamB; Laminin B domain
    smart00282
    Location:2246 → 2388
    LamG; Laminin G domain
    cd00055
    Location:903 → 944
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3078 → 3229
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR04527
    Location:1902 → 2012
    mycoplas_twoTM; two transmembrane protein
    pfam00052
    Location:569 → 698
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1497 → 1543
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2916 → 3043
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:39 → 274
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06008
    Location:1675 → 1928
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2128 → 2249
    Laminin_II; Laminin Domain II
    cl21509
    Location:1839 → 1932
    ApoLp-III_like; Apolipophorin-III and similar insect proteins

  6. XM_015369222.1 → XP_015224708.1  laminin subunit alpha-2 isoform X6

    UniProtKB/TrEMBL
    A0A3Q2C9Y8
    Conserved Domains (13) summary
    smart00180
    Location:1045 → 1089
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1306 → 1435
    LamB; Laminin B domain
    smart00282
    Location:2200 → 2342
    LamG; Laminin G domain
    cd00055
    Location:903 → 944
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3032 → 3183
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR04527
    Location:1856 → 1966
    mycoplas_twoTM; two transmembrane protein
    pfam00052
    Location:569 → 698
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1497 → 1543
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2870 → 2997
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:39 → 274
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06008
    Location:1629 → 1882
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2082 → 2203
    Laminin_II; Laminin Domain II
    cl21509
    Location:1793 → 1886
    ApoLp-III_like; Apolipophorin-III and similar insect proteins

  7. XM_015369230.1 → XP_015224716.1  laminin subunit alpha-2 isoform X7

    UniProtKB/TrEMBL
    A0A3Q2C9Y8
    Conserved Domains (13) summary
    smart00180
    Location:953 → 997
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1214 → 1343
    LamB; Laminin B domain
    smart00282
    Location:2154 → 2296
    LamG; Laminin G domain
    cd00055
    Location:903 → 948
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2990 → 3141
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR04527
    Location:1810 → 1920
    mycoplas_twoTM; two transmembrane protein
    pfam00052
    Location:569 → 698
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1405 → 1451
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2828 → 2955
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:39 → 274
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06008
    Location:1583 → 1836
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2036 → 2157
    Laminin_II; Laminin Domain II
    cl21509
    Location:1747 → 1840
    ApoLp-III_like; Apolipophorin-III and similar insect proteins

  8. XM_015369234.1 → XP_015224720.1  laminin subunit alpha-2 isoform X8

    UniProtKB/TrEMBL
    A0A3Q2C9Y8
    Related
    ENSCVAP00000001552.1, ENSCVAT00000013225.1
    Conserved Domains (13) summary
    smart00180
    Location:953 → 997
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1214 → 1343
    LamB; Laminin B domain
    smart00282
    Location:2152 → 2294
    LamG; Laminin G domain
    cd00055
    Location:903 → 948
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2984 → 3135
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR04527
    Location:1810 → 1920
    mycoplas_twoTM; two transmembrane protein
    pfam00052
    Location:569 → 698
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1405 → 1451
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2822 → 2949
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:39 → 274
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06008
    Location:1583 → 1836
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2036 → 2155
    Laminin_II; Laminin Domain II
    cl21509
    Location:1747 → 1840
    ApoLp-III_like; Apolipophorin-III and similar insect proteins

  9. XM_015369237.1 → XP_015224723.1  laminin subunit alpha-2 isoform X9

    UniProtKB/TrEMBL
    A0A3Q2C9Y8
    Conserved Domains (13) summary
    smart00180
    Location:953 → 997
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1214 → 1343
    LamB; Laminin B domain
    smart00282
    Location:2106 → 2248
    LamG; Laminin G domain
    cd00055
    Location:903 → 948
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2938 → 3089
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR04527
    Location:1764 → 1874
    mycoplas_twoTM; two transmembrane protein
    pfam00052
    Location:569 → 698
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1405 → 1451
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2776 → 2903
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:39 → 274
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06008
    Location:1537 → 1790
    Laminin_I; Laminin Domain I
    pfam06009
    Location:1990 → 2109
    Laminin_II; Laminin Domain II
    cl21509
    Location:1701 → 1794
    ApoLp-III_like; Apolipophorin-III and similar insect proteins
Nucleotide Protein
Heading Accession and Version

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