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lama2 laminin, alpha 2 [ Poecilia latipinna (sailfin molly) ]

Gene ID: 106962596, updated on 13-Mar-2024

Summary

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Gene symbol
lama2
Gene description
laminin, alpha 2
See related
Ensembl:ENSPLAG00000019881
Gene type
protein coding
RefSeq status
MODEL
Organism
Poecilia latipinna
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Poecilia
Orthologs
human zebrafish all
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Genomic context

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See lama2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
74
Annotation release Status Assembly Chr Location
100 current P_latipinna-1.0 (GCF_001443285.1) Unplaced Scaffold NW_015112677.1 (76458..243254, complement)

NW_015112677.1Genomic Context describing neighboring genes Neighboring gene regulator of G-protein signaling 6-like Neighboring gene vesicular inhibitory amino acid transporter-like Neighboring gene protein tyrosine phosphatase receptor type K

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_015112677.1 Unplaced Scaffold Reference P_latipinna-1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of embryonic development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
laminin subunit alpha-2
Names
laminin subunit alpha 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Poecilia latipinna Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P_latipinna-1.0

Genomic

  1. NW_015112677.1 Reference P_latipinna-1.0

    Range
    76458..243254 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015057151.1 → XP_014912637.1  laminin subunit alpha-2 isoform X6

    UniProtKB/TrEMBL
    A0A3B3VUS6
    Related
    ENSPLAP00000029550.1, ENSPLAT00000030836.1
    Conserved Domains (11) summary
    smart00180
    Location:953 → 997
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1214 → 1343
    LamB; Laminin B domain
    cd00055
    Location:903 → 948
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2989 → 3140
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00052
    Location:569 → 697
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1405 → 1451
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2822 → 2949
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:39 → 274
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06008
    Location:1583 → 1834
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2036 → 2155
    Laminin_II; Laminin Domain II
    pfam16043
    Location:1700 → 1887
    DUF4795; Domain of unknown function (DUF4795)

  2. XM_015057145.1 → XP_014912631.1  laminin subunit alpha-2 isoform X5

    UniProtKB/TrEMBL
    A0A3B3VUS6
    Conserved Domains (11) summary
    smart00180
    Location:953 → 997
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1214 → 1343
    LamB; Laminin B domain
    cd00055
    Location:903 → 948
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2991 → 3142
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00052
    Location:569 → 697
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1405 → 1451
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2824 → 2951
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:39 → 274
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06008
    Location:1583 → 1834
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2036 → 2157
    Laminin_II; Laminin Domain II
    pfam16043
    Location:1700 → 1887
    DUF4795; Domain of unknown function (DUF4795)

  3. XM_015057136.1 → XP_014912622.1  laminin subunit alpha-2 isoform X4

    UniProtKB/TrEMBL
    A0A3B3VUS6
    Conserved Domains (11) summary
    smart00180
    Location:1045 → 1089
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1306 → 1435
    LamB; Laminin B domain
    cd00055
    Location:903 → 946
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3037 → 3188
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00052
    Location:569 → 697
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1497 → 1543
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2870 → 2997
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:39 → 274
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06008
    Location:1629 → 1880
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2082 → 2203
    Laminin_II; Laminin Domain II
    pfam16043
    Location:1746 → 1933
    DUF4795; Domain of unknown function (DUF4795)

  4. XM_015057116.1 → XP_014912602.1  laminin subunit alpha-2 isoform X2

    UniProtKB/TrEMBL
    A0A3B3VUS6
    Conserved Domains (11) summary
    smart00180
    Location:1045 → 1089
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1306 → 1435
    LamB; Laminin B domain
    cd00055
    Location:903 → 946
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3081 → 3232
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00052
    Location:569 → 697
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1497 → 1543
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2914 → 3041
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:39 → 274
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06008
    Location:1675 → 1926
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2128 → 2247
    Laminin_II; Laminin Domain II
    pfam16043
    Location:1792 → 1979
    DUF4795; Domain of unknown function (DUF4795)

  5. XM_015057127.1 → XP_014912613.1  laminin subunit alpha-2 isoform X3

    UniProtKB/TrEMBL
    A0A3B3VUS6
    Conserved Domains (11) summary
    smart00180
    Location:1045 → 1089
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1306 → 1435
    LamB; Laminin B domain
    cd00055
    Location:903 → 946
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3052 → 3203
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00052
    Location:569 → 697
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1497 → 1543
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2885 → 3012
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:39 → 274
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06008
    Location:1675 → 1926
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2128 → 2249
    Laminin_II; Laminin Domain II
    pfam16043
    Location:1792 → 1979
    DUF4795; Domain of unknown function (DUF4795)

  6. XM_015057105.1 → XP_014912591.1  laminin subunit alpha-2 isoform X1

    UniProtKB/TrEMBL
    A0A3B3VUS6
    Conserved Domains (11) summary
    smart00180
    Location:1045 → 1089
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1306 → 1435
    LamB; Laminin B domain
    cd00055
    Location:903 → 946
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3083 → 3234
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00052
    Location:569 → 697
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1497 → 1543
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2916 → 3043
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:39 → 274
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06008
    Location:1675 → 1926
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2128 → 2249
    Laminin_II; Laminin Domain II
    pfam16043
    Location:1792 → 1979
    DUF4795; Domain of unknown function (DUF4795)

  7. XM_015057159.1 → XP_014912645.1  laminin subunit alpha-2 isoform X7

    UniProtKB/TrEMBL
    A0A3B3VUS6
    Conserved Domains (11) summary
    smart00180
    Location:953 → 997
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1214 → 1343
    LamB; Laminin B domain
    cd00055
    Location:903 → 948
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2943 → 3094
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00052
    Location:569 → 697
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1405 → 1451
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2776 → 2903
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:39 → 274
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06008
    Location:1537 → 1788
    Laminin_I; Laminin Domain I
    pfam06009
    Location:1990 → 2109
    Laminin_II; Laminin Domain II
    pfam16043
    Location:1654 → 1841
    DUF4795; Domain of unknown function (DUF4795)
Nucleotide Protein
Heading Accession and Version

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