U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PDIA3 protein disulfide isomerase family A member 3 [ Equus asinus (ass) ]

Gene ID: 106835017, updated on 13-Mar-2024

Summary

Gene symbol
PDIA3
Gene description
protein disulfide isomerase family A member 3
See related
Ensembl:ENSEASG00005004953
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus asinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See PDIA3 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
13
Annotation release Status Assembly Chr Location
101 current ASM1607732v2 (GCF_016077325.2) 2 NC_052178.1 (190058403..190079406, complement)
100 previous assembly ASM130575v1 (GCF_001305755.1) Unplaced Scaffold NW_014637989.1 (2414698..2435694, complement)

Chromosome 2 - NC_052178.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC123282972 Neighboring gene small EDRK-rich factor 2 Neighboring gene elongation factor for RNA polymerase II 3 Neighboring gene cation channel sperm associated 2 Neighboring gene stereocilin

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein disulfide isomerase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in protein folding IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in response to endoplasmic reticulum stress IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
protein disulfide-isomerase A3

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Equus asinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1607732v2

Genomic

  1. NC_052178.1 Reference ASM1607732v2

    Range
    190058403..190079406 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014847105.2XP_014702591.1  protein disulfide-isomerase A3

    UniProtKB/TrEMBL
    A0A8C4LHC4
    Related
    ENSEASP00005008026.2, ENSEAST00005008759.2
    Conserved Domains (5) summary
    cd02995
    Location:377480
    PDI_a_PDI_a'_C; PDIa family, C-terminal TRX domain (a') subfamily; composed of the C-terminal redox active a' domains of PDI, ERp72, ERp57 (or ERp60) and EFP1. PDI, ERp72 and ERp57 are endoplasmic reticulum (ER)-resident eukaryotic proteins involved in oxidative protein ...
    cd03069
    Location:135240
    PDI_b_ERp57; PDIb family, ERp57 subfamily, first redox inactive TRX-like domain b; ERp57 (or ERp60) exhibits both disulfide oxidase and reductase functions like PDI, by catalyzing the formation of disulfide bonds of newly synthesized polypeptides in the ER and acting ...
    cd03073
    Location:244357
    PDI_b'_ERp72_ERp57; PDIb' family, ERp72 and ERp57 subfamily, second redox inactive TRX-like domain b'; ERp72 and ER57 are involved in oxidative protein folding in the ER, like PDI. They exhibit both disulfide oxidase and reductase functions, by catalyzing the formation of ...
    TIGR01130
    Location:25487
    ER_PDI_fam; protein disulfide isomerase, eukaryotic
    pfam00085
    Location:27131
    Thioredoxin; Thioredoxin