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Ago2 argonaute RISC catalytic component 2 [ Dipodomys ordii (Ord's kangaroo rat) ]

Gene ID: 105992362, updated on 13-Mar-2024

Summary

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Gene symbol
Ago2
Gene description
argonaute RISC catalytic component 2
See related
Ensembl:ENSDORG00000011242
Gene type
protein coding
RefSeq status
MODEL
Organism
Dipodomys ordii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae; Dipodomyinae; Dipodomys
Orthologs
human mouse all
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Genomic context

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See Ago2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
18
Annotation release Status Assembly Chr Location
100 current Dord_2.0 (GCF_000151885.1) Unplaced Scaffold NW_012267298.1 (10964978..11004627, complement)

NW_012267298.1Genomic Context describing neighboring genes Neighboring gene trafficking protein particle complex subunit 9 Neighboring gene chromatin accessibility complex subunit 1 Neighboring gene protein tyrosine kinase 2 Neighboring gene DENN domain containing 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012267298.1 Unplaced Scaffold Reference Dord_2.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables endoribonuclease activity, cleaving siRNA-paired mRNA IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulatory ncRNA-mediated gene silencing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of RISC complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein argonaute-2
Names
argonaute 2, RISC catalytic component

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Dipodomys ordii Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Dord_2.0

Genomic

  1. NW_012267298.1 Reference Dord_2.0

    Range
    10964978..11004627 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013025215.1 → XP_012880669.1  protein argonaute-2

    UniProtKB/TrEMBL
    A0A1S3FXC0
    Related
    ENSDORP00000017829.1, ENSDORT00000032435.1
    Conserved Domains (5) summary
    PLN03202
    Location:1 → 812
    PLN03202; protein argonaute; Provisional
    cd02846
    Location:181 → 301
    PAZ_argonaute_like; PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille. ...
    cd04657
    Location:346 → 771
    Piwi_ago-like; Piwi_ago-like: PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of ...
    pfam08699
    Location:131 → 180
    ArgoL1; Argonaute linker 1 domain
    pfam16486
    Location:1 → 120
    ArgoN; N-terminal domain of argonaute
Nucleotide Protein
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