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ACACA acetyl-CoA carboxylase alpha [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105879961, updated on 13-Mar-2024

Summary

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Gene symbol
ACACA
Gene description
acetyl-CoA carboxylase alpha
See related
Ensembl:ENSMICG00000004237
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
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Genomic context

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See ACACA in Genome Data Viewer
Location:
chromosome: 16
Exon count:
56
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 16 NC_033675.1 (14171779..14420937)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012195040.1 (9374818..9624146, complement)

Chromosome 16 - NC_033675.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105880122 Neighboring gene transcriptional adaptor 2A Neighboring gene chromosome 16 C17orf78 homolog Neighboring gene uncharacterized LOC105880074 Neighboring gene apoptosis antagonizing transcription factor Neighboring gene LIM homeobox 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables acetyl-CoA carboxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
acetyl-CoA carboxylase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033675.1 Reference Mmur_3.0 Primary Assembly

    Range
    14171779..14420937
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012780669.2 → XP_012636123.1  acetyl-CoA carboxylase 1

    UniProtKB/TrEMBL
    A0A8B7HG92, A0A8C5UPV1
    Related
    ENSMICP00000003879.3, ENSMICT00000004254.3
    Conserved Domains (8) summary
    COG0439
    Location:169 → 671
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    COG0511
    Location:722 → 869
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]
    pfam00289
    Location:169 → 288
    CPSase_L_chain; Carbamoyl-phosphate synthase L chain, N-terminal domain
    pfam00364
    Location:804 → 869
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1720 → 2268
    Carboxyl_trans; Carboxyl transferase domain
    pfam02785
    Location:558 → 665
    Biotin_carb_C; Biotin carboxylase C-terminal domain
    pfam08326
    Location:871 → 1620
    ACC_central; Acetyl-CoA carboxylase, central region
    cl17255
    Location:330 → 521
    ATP-grasp_4; ATP-grasp domain
Nucleotide Protein
Heading Accession and Version

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