2K7V,2DN8,2JKU,3BG3,1IYU,1GHJ


Conserved Protein Domain Family
Biotin_lipoyl
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pfam00364: Biotin_lipoyl (this model, PSSM-Id:278778 is obsolete and has been replaced by 395290)
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Biotin-requiring enzyme
This family covers two Prosite entries, the conserved lysine residue binds biotin in one group and lipoic acid in the other. Note that the HMM does not currently recognize the Glycine cleavage system H proteins.
Links
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Statistics
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PSSM-Id: 278778
Aligned: 41 rows
Threshold Bit Score: 59.158
Created: 15-Jun-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2K7V_B      3 KEVNVPDI----V--E---VTEVMVKVGDKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIMIF 70   Escherichia coli K-12
P43874     80 HLVRSPMVgtfyR--SpspEAKAFVEVGQSVKVGDALCIVEAMKMMNRIEADKAGVVKAILINDGNAVEFDEPLIVI 154  Haemophilus influenz...
P37799     81 NVVRSPMVgtfyR--AaspTSANFVEVGQSVKKGDILCIVEAMKMMNHIEAEVSGTIESILVENGQPVEFDQPLFTI 155  Pseudomonas aerugino...
Q06881    105 AEVASPMVgtfyR--ApapGEAVFVEVGDRIRQGQTVCIIEAMKLMNEIEADVSGQVIEILVQNGEPVEYNQPLMRI 179  Nostoc sp. PCC 7120
Q42783    186 PPLKSPMAgtfyR--SpapGEPSFVKVGDKVKKGQVVCIIEAMKLMNEIEADQSGTIVEIVAEDAKSVSVDTPLFVI 260  soybean
Q42533    204 PTVKSPMAgtfyR--SpapGEPPFIKVGDKVQKGQVLCIVEAMKLMNEIESDHTGTVVDIVAEDGKPVSLDTPLFVV 278  thale cress
3BG3_D    650 GQIGAPMPgkviD---------IKVVAGAKVAKGQPLCVLSAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEI 717  human
P32327   1102 HQIGAPMAgviiE---------VKVHKGSLVKKGESIAVLSAMKMEMVVSSPADGQVKDVFIKDGESVDASDLLVVL 1169 Saccharomyces cerevi...
P11154   1101 LHIGAPMAgvivE---------VKVHKGSLIKKGQPVAVLSAMKMEMIISSPSDGQVKEVFVSDGENVDSSDLLVLL 1168 Saccharomyces cerevi...
AAT64974  416 HIVRSPMVgtfyRtpSp--DAKAFIEVGQKVNVGDTLCIVEAMKMMNQIEADKSGTVKAILVESGQPVEFDEPLVVI 490  synthetic construct
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