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ACACB acetyl-CoA carboxylase beta [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105866938, updated on 13-Mar-2024

Summary

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Gene symbol
ACACB
Gene description
acetyl-CoA carboxylase beta
See related
Ensembl:ENSMICG00000043665
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
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Genomic context

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See ACACB in Genome Data Viewer
Location:
chromosome: 21
Exon count:
55
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 21 NC_033680.1 (10878561..10991546, complement)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012203685.1 (5846349..5959320, complement)

Chromosome 21 - NC_033680.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105866893 Neighboring gene uncharacterized LOC105866996 Neighboring gene forkhead box N4 Neighboring gene proteasome subunit alpha type-6 pseudogene Neighboring gene uracil DNA glycosylase Neighboring gene alkB homolog 2, alpha-ketoglutarate dependent dioxygenase Neighboring gene ubiquitin specific peptidase 30

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables acetyl-CoA carboxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
acetyl-CoA carboxylase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033680.1 Reference Mmur_3.0 Primary Assembly

    Range
    10878561..10991546 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012756614.2 → XP_012612068.1  acetyl-CoA carboxylase 2 isoform X1

    See identical proteins and their annotated locations for XP_012612068.1

    UniProtKB/TrEMBL
    A0A8B7FSK2
    Related
    ENSMICP00000042018.1, ENSMICT00000063310.1
    Conserved Domains (8) summary
    COG0439
    Location:262 → 765
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    pfam00289
    Location:262 → 381
    CPSase_L_chain; Carbamoyl-phosphate synthase L chain, N-terminal domain
    pfam00364
    Location:897 → 963
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1782 → 2330
    Carboxyl_trans; Carboxyl transferase domain
    pfam02785
    Location:652 → 759
    Biotin_carb_C; Biotin carboxylase C-terminal domain
    pfam08326
    Location:964 → 1690
    ACC_central; Acetyl-CoA carboxylase, central region
    cl17255
    Location:434 → 615
    ATP-grasp_4; ATP-grasp domain
    cl23717
    Location:2066 → 2104
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...

  2. XM_012756613.2 → XP_012612067.1  acetyl-CoA carboxylase 2 isoform X1

    See identical proteins and their annotated locations for XP_012612067.1

    UniProtKB/TrEMBL
    A0A8B7FSK2
    Conserved Domains (8) summary
    COG0439
    Location:262 → 765
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    pfam00289
    Location:262 → 381
    CPSase_L_chain; Carbamoyl-phosphate synthase L chain, N-terminal domain
    pfam00364
    Location:897 → 963
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1782 → 2330
    Carboxyl_trans; Carboxyl transferase domain
    pfam02785
    Location:652 → 759
    Biotin_carb_C; Biotin carboxylase C-terminal domain
    pfam08326
    Location:964 → 1690
    ACC_central; Acetyl-CoA carboxylase, central region
    cl17255
    Location:434 → 615
    ATP-grasp_4; ATP-grasp domain
    cl23717
    Location:2066 → 2104
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...

  3. XM_012756617.2 → XP_012612071.1  acetyl-CoA carboxylase 2 isoform X2

    UniProtKB/TrEMBL
    A0A8B7FTK6
    Conserved Domains (8) summary
    COG0439
    Location:81 → 584
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    pfam00289
    Location:81 → 200
    CPSase_L_chain; Carbamoyl-phosphate synthase L chain, N-terminal domain
    pfam00364
    Location:716 → 782
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1601 → 2149
    Carboxyl_trans; Carboxyl transferase domain
    pfam02785
    Location:471 → 578
    Biotin_carb_C; Biotin carboxylase C-terminal domain
    pfam08326
    Location:783 → 1509
    ACC_central; Acetyl-CoA carboxylase, central region
    cl17255
    Location:253 → 434
    ATP-grasp_4; ATP-grasp domain
    cl23717
    Location:1885 → 1923
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
Nucleotide Protein
Heading Accession and Version

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