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MTIF2 mitochondrial translational initiation factor 2 [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105576396, updated on 13-Mar-2024

Summary

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Gene symbol
MTIF2
Gene description
mitochondrial translational initiation factor 2
See related
Ensembl:ENSCATG00000038926
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Orthologs
human mouse all
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Genomic context

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See MTIF2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
19
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012004605.1 (2269447..2301364, complement)

NW_012004605.1Genomic Context describing neighboring genes Neighboring gene reticulon 4 Neighboring gene uncharacterized LOC105576392 Neighboring gene clathrin heavy chain linker domain containing 1 Neighboring gene ribosomal protein S27a Neighboring gene putative prolyl-tRNA synthetase associated domain-containing protein 1 Neighboring gene coiled-coil domain containing 88A Neighboring gene uncharacterized LOC105576403

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012004605.1 Unplaced Scaffold Reference Caty_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in translational initiation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
translation initiation factor IF-2, mitochondrial

NCBI Reference Sequences (RefSeq)

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NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012004605.1 Reference Caty_1.0

    Range
    2269447..2301364 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012039413.1 → XP_011894803.1  translation initiation factor IF-2, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_011894803.1

    UniProtKB/TrEMBL
    A0A2K5N2R0
    Conserved Domains (5) summary
    cd01887
    Location:181 → 345
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:176 → 718
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:515 → 606
    IF-2; Translation-initiation factor 2
    cd03692
    Location:624 → 711
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:354 → 448
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

  2. XM_012039421.1 → XP_011894811.1  translation initiation factor IF-2, mitochondrial isoform X2

    See identical proteins and their annotated locations for XP_011894811.1

    Conserved Domains (5) summary
    cd01887
    Location:85 → 249
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:80 → 622
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:419 → 510
    IF-2; Translation-initiation factor 2
    cd03692
    Location:528 → 615
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:258 → 352
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

  3. XM_012039410.1 → XP_011894800.1  translation initiation factor IF-2, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_011894800.1

    UniProtKB/TrEMBL
    A0A2K5N2R0
    Conserved Domains (5) summary
    cd01887
    Location:181 → 345
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:176 → 718
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:515 → 606
    IF-2; Translation-initiation factor 2
    cd03692
    Location:624 → 711
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:354 → 448
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

  4. XM_012039414.1 → XP_011894804.1  translation initiation factor IF-2, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_011894804.1

    UniProtKB/TrEMBL
    A0A2K5N2R0
    Conserved Domains (5) summary
    cd01887
    Location:181 → 345
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:176 → 718
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:515 → 606
    IF-2; Translation-initiation factor 2
    cd03692
    Location:624 → 711
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:354 → 448
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

  5. XM_012039412.1 → XP_011894802.1  translation initiation factor IF-2, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_011894802.1

    UniProtKB/TrEMBL
    A0A2K5N2R0
    Conserved Domains (5) summary
    cd01887
    Location:181 → 345
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:176 → 718
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:515 → 606
    IF-2; Translation-initiation factor 2
    cd03692
    Location:624 → 711
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:354 → 448
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

  6. XM_012039408.1 → XP_011894798.1  translation initiation factor IF-2, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_011894798.1

    UniProtKB/TrEMBL
    A0A2K5N2R0
    Conserved Domains (5) summary
    cd01887
    Location:181 → 345
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:176 → 718
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:515 → 606
    IF-2; Translation-initiation factor 2
    cd03692
    Location:624 → 711
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:354 → 448
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

  7. XM_012039407.1 → XP_011894797.1  translation initiation factor IF-2, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_011894797.1

    UniProtKB/TrEMBL
    A0A2K5N2R0
    Conserved Domains (5) summary
    cd01887
    Location:181 → 345
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:176 → 718
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:515 → 606
    IF-2; Translation-initiation factor 2
    cd03692
    Location:624 → 711
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:354 → 448
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

  8. XM_012039411.1 → XP_011894801.1  translation initiation factor IF-2, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_011894801.1

    UniProtKB/TrEMBL
    A0A2K5N2R0
    Conserved Domains (5) summary
    cd01887
    Location:181 → 345
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:176 → 718
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:515 → 606
    IF-2; Translation-initiation factor 2
    cd03692
    Location:624 → 711
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:354 → 448
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

  9. XM_012039403.1 → XP_011894793.1  translation initiation factor IF-2, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_011894793.1

    UniProtKB/TrEMBL
    A0A2K5N2R0
    Conserved Domains (5) summary
    cd01887
    Location:181 → 345
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:176 → 718
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:515 → 606
    IF-2; Translation-initiation factor 2
    cd03692
    Location:624 → 711
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:354 → 448
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

  10. XM_012039406.1 → XP_011894796.1  translation initiation factor IF-2, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_011894796.1

    UniProtKB/TrEMBL
    A0A2K5N2R0
    Conserved Domains (5) summary
    cd01887
    Location:181 → 345
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:176 → 718
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:515 → 606
    IF-2; Translation-initiation factor 2
    cd03692
    Location:624 → 711
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:354 → 448
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

  11. XM_012039404.1 → XP_011894794.1  translation initiation factor IF-2, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_011894794.1

    UniProtKB/TrEMBL
    A0A2K5N2R0
    Conserved Domains (5) summary
    cd01887
    Location:181 → 345
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:176 → 718
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:515 → 606
    IF-2; Translation-initiation factor 2
    cd03692
    Location:624 → 711
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:354 → 448
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

  12. XM_012039400.1 → XP_011894790.1  translation initiation factor IF-2, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_011894790.1

    UniProtKB/TrEMBL
    A0A2K5N2R0
    Conserved Domains (5) summary
    cd01887
    Location:181 → 345
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:176 → 718
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:515 → 606
    IF-2; Translation-initiation factor 2
    cd03692
    Location:624 → 711
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:354 → 448
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

  13. XM_012039402.1 → XP_011894792.1  translation initiation factor IF-2, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_011894792.1

    UniProtKB/TrEMBL
    A0A2K5N2R0
    Conserved Domains (5) summary
    cd01887
    Location:181 → 345
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:176 → 718
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:515 → 606
    IF-2; Translation-initiation factor 2
    cd03692
    Location:624 → 711
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:354 → 448
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

  14. XM_012039401.1 → XP_011894791.1  translation initiation factor IF-2, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_011894791.1

    UniProtKB/TrEMBL
    A0A2K5N2R0
    Conserved Domains (5) summary
    cd01887
    Location:181 → 345
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:176 → 718
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:515 → 606
    IF-2; Translation-initiation factor 2
    cd03692
    Location:624 → 711
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:354 → 448
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

  15. XM_012039415.1 → XP_011894805.1  translation initiation factor IF-2, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_011894805.1

    UniProtKB/TrEMBL
    A0A2K5N2R0
    Conserved Domains (5) summary
    cd01887
    Location:181 → 345
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:176 → 718
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:515 → 606
    IF-2; Translation-initiation factor 2
    cd03692
    Location:624 → 711
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:354 → 448
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

  16. XM_012039409.1 → XP_011894799.1  translation initiation factor IF-2, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_011894799.1

    UniProtKB/TrEMBL
    A0A2K5N2R0
    Conserved Domains (5) summary
    cd01887
    Location:181 → 345
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:176 → 718
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:515 → 606
    IF-2; Translation-initiation factor 2
    cd03692
    Location:624 → 711
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:354 → 448
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

  17. XM_012039420.1 → XP_011894810.1  translation initiation factor IF-2, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_011894810.1

    UniProtKB/TrEMBL
    A0A2K5N2R0
    Related
    ENSCATP00000031610.1, ENSCATT00000055876.1
    Conserved Domains (5) summary
    cd01887
    Location:181 → 345
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:176 → 718
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:515 → 606
    IF-2; Translation-initiation factor 2
    cd03692
    Location:624 → 711
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:354 → 448
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

  18. XM_012039417.1 → XP_011894807.1  translation initiation factor IF-2, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_011894807.1

    UniProtKB/TrEMBL
    A0A2K5N2R0
    Conserved Domains (5) summary
    cd01887
    Location:181 → 345
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:176 → 718
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:515 → 606
    IF-2; Translation-initiation factor 2
    cd03692
    Location:624 → 711
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:354 → 448
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

  19. XM_012039419.1 → XP_011894809.1  translation initiation factor IF-2, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_011894809.1

    UniProtKB/TrEMBL
    A0A2K5N2R0
    Conserved Domains (5) summary
    cd01887
    Location:181 → 345
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:176 → 718
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:515 → 606
    IF-2; Translation-initiation factor 2
    cd03692
    Location:624 → 711
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:354 → 448
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

  20. XM_012039418.1 → XP_011894808.1  translation initiation factor IF-2, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_011894808.1

    UniProtKB/TrEMBL
    A0A2K5N2R0
    Conserved Domains (5) summary
    cd01887
    Location:181 → 345
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:176 → 718
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:515 → 606
    IF-2; Translation-initiation factor 2
    cd03692
    Location:624 → 711
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:354 → 448
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

  21. XM_012039423.1 → XP_011894813.1  translation initiation factor IF-2, mitochondrial isoform X2

    See identical proteins and their annotated locations for XP_011894813.1

    Conserved Domains (5) summary
    cd01887
    Location:85 → 249
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:80 → 622
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:419 → 510
    IF-2; Translation-initiation factor 2
    cd03692
    Location:528 → 615
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:258 → 352
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2

  22. XM_012039422.1 → XP_011894812.1  translation initiation factor IF-2, mitochondrial isoform X2

    See identical proteins and their annotated locations for XP_011894812.1

    Conserved Domains (5) summary
    cd01887
    Location:85 → 249
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:80 → 622
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam11987
    Location:419 → 510
    IF-2; Translation-initiation factor 2
    cd03692
    Location:528 → 615
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:258 → 352
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2
Nucleotide Protein
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