U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MASP1 MBL associated serine protease 1 [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105575210, updated on 13-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
MASP1
Gene description
MBL associated serine protease 1
See related
Ensembl:ENSCATG00000018550
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See MASP1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
19
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012004056.1 (10510161..10586207)

NW_012004056.1Genomic Context describing neighboring genes Neighboring gene somatostatin Neighboring gene uncharacterized LOC105575212 Neighboring gene receptor transporter protein 4 Neighboring gene receptor transporter protein 1 Neighboring gene uncharacterized LOC105575209 Neighboring gene uncharacterized LOC105575213

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NW_012004056.1 Unplaced Scaffold Reference Caty_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in zymogen activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in blood microparticle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
mannan-binding lectin serine protease 1
Names
mannan binding lectin serine peptidase 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012004056.1 Reference Caty_1.0

    Range
    10510161..10586207
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012036883.1 → XP_011892273.1  mannan-binding lectin serine protease 1 isoform X5

    Conserved Domains (7) summary
    cd00033
    Location:270 → 332
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00020
    Location:418 → 680
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:419 → 680
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:336 → 401
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:154 → 263
    CUB; CUB domain
    pfam14670
    Location:122 → 150
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00049
    Location:50 → 106
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

  2. XM_012036882.1 → XP_011892272.1  mannan-binding lectin serine protease 1 isoform X4

    UniProtKB/TrEMBL
    A0A2K5KYU0
    Related
    ENSCATP00000005866.1, ENSCATT00000021515.1
    Conserved Domains (7) summary
    cd00033
    Location:301 → 363
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00020
    Location:448 → 691
    Tryp_SPc; Trypsin-like serine protease
    cd00041
    Location:28 → 137
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:449 → 694
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:367 → 432
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:185 → 294
    CUB; CUB domain
    pfam14670
    Location:153 → 181
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  3. XM_012036880.1 → XP_011892270.1  mannan-binding lectin serine protease 1 isoform X2

    UniProtKB/TrEMBL
    A0A2K5KYV3
    Related
    ENSCATP00000005877.1, ENSCATT00000021535.1
    Conserved Domains (7) summary
    cd00033
    Location:301 → 363
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00020
    Location:449 → 711
    Tryp_SPc; Trypsin-like serine protease
    cd00041
    Location:28 → 137
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:450 → 711
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:367 → 432
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:185 → 294
    CUB; CUB domain
    pfam14670
    Location:153 → 181
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  4. XM_012036881.1 → XP_011892271.1  mannan-binding lectin serine protease 1 isoform X3

    Conserved Domains (7) summary
    cd00033
    Location:308 → 370
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00020
    Location:455 → 698
    Tryp_SPc; Trypsin-like serine protease
    cd00041
    Location:35 → 144
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:456 → 701
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:374 → 439
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:192 → 301
    CUB; CUB domain
    pfam14670
    Location:160 → 188
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  5. XM_012036886.1 → XP_011892276.1  mannan-binding lectin serine protease 1 isoform X7

    Conserved Domains (7) summary
    cd00033
    Location:308 → 370
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00020
    Location:455 → 583
    Tryp_SPc; Trypsin-like serine protease
    cd00041
    Location:35 → 144
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:456 → 586
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:374 → 439
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:192 → 301
    CUB; CUB domain
    pfam14670
    Location:160 → 188
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  6. XM_012036879.1 → XP_011892269.1  mannan-binding lectin serine protease 1 isoform X1

    Conserved Domains (7) summary
    cd00033
    Location:308 → 370
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00020
    Location:456 → 718
    Tryp_SPc; Trypsin-like serine protease
    cd00041
    Location:35 → 144
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:457 → 718
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:374 → 439
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:192 → 301
    CUB; CUB domain
    pfam14670
    Location:160 → 188
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  7. XM_012036887.1 → XP_011892277.1  mannan-binding lectin serine protease 1 isoform X8

    UniProtKB/TrEMBL
    A0A2K5KYX7
    Related
    ENSCATP00000005888.1, ENSCATT00000021562.1
    Conserved Domains (4) summary
    cd00033
    Location:308 → 370
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    cd00041
    Location:35 → 144
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00431
    Location:192 → 301
    CUB; CUB domain
    pfam14670
    Location:160 → 188
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  8. XM_012036885.1 → XP_011892275.1  mannan-binding lectin serine protease 1 isoform X6

    See identical proteins and their annotated locations for XP_011892275.1

    Conserved Domains (7) summary
    cd00033
    Location:188 → 250
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00020
    Location:336 → 598
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:337 → 598
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:254 → 319
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:72 → 181
    CUB; CUB domain
    pfam14670
    Location:40 → 68
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00057
    Location:8 → 67
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  9. XM_012036884.1 → XP_011892274.1  mannan-binding lectin serine protease 1 isoform X6

    See identical proteins and their annotated locations for XP_011892274.1

    Conserved Domains (7) summary
    cd00033
    Location:188 → 250
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00020
    Location:336 → 598
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:337 → 598
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:254 → 319
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:72 → 181
    CUB; CUB domain
    pfam14670
    Location:40 → 68
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00057
    Location:8 → 67
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.