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ACACA acetyl-CoA carboxylase alpha [ Colobus angolensis palliatus ]

Gene ID: 105520050, updated on 13-Mar-2024

Summary

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Gene symbol
ACACA
Gene description
acetyl-CoA carboxylase alpha
See related
Ensembl:ENSCANG00000027168
Gene type
protein coding
RefSeq status
MODEL
Organism
Colobus angolensis palliatus (sub-species: palliatus)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Colobus
Orthologs
human mouse all
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Genomic context

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See ACACA in Genome Data Viewer
Location:
chromosome: Un
Exon count:
62
Annotation release Status Assembly Chr Location
100 current Cang.pa_1.0 (GCF_000951035.1) Unplaced Scaffold NW_012117043.1 (505515..865979)

NW_012117043.1Genomic Context describing neighboring genes Neighboring gene dual specificity phosphatase 14 Neighboring gene transcriptional adaptor 2A Neighboring gene chromosome unknown open reading frame, human C17orf78 Neighboring gene 40S ribosomal protein S2 pseudogene Neighboring gene apoptosis antagonizing transcription factor Neighboring gene LIM homeobox 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012117043.1 Unplaced Scaffold Reference Cang.pa_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables acetyl-CoA carboxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
acetyl-CoA carboxylase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Colobus angolensis palliatus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Cang.pa_1.0

Genomic

  1. NW_012117043.1 Reference Cang.pa_1.0

    Range
    505515..865979
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011953628.1 → XP_011809018.1  acetyl-CoA carboxylase 1 isoform X2

    See identical proteins and their annotated locations for XP_011809018.1

    UniProtKB/TrEMBL
    A0A2K5HV90, A0A2K5HVR2
    Conserved Domains (5) summary
    COG0439
    Location:118 → 620
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    pfam00364
    Location:753 → 818
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1669 → 2217
    Carboxyl_trans; Carboxyl transferase domain
    pfam08326
    Location:820 → 1562
    ACC_central; Acetyl-CoA carboxylase, central region
    cl27427
    Location:671 → 818
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]

  2. XM_011953625.1 → XP_011809015.1  acetyl-CoA carboxylase 1 isoform X1

    UniProtKB/TrEMBL
    A0A2K5HVE8, A0A2K5HVH0
    Related
    ENSCANP00000008297.1, ENSCANT00000030894.1
    Conserved Domains (8) summary
    COG0439
    Location:155 → 657
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    COG0511
    Location:708 → 855
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]
    pfam00289
    Location:155 → 274
    CPSase_L_chain; Carbamoyl-phosphate synthase L chain, N-terminal domain
    pfam00364
    Location:790 → 855
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1706 → 2254
    Carboxyl_trans; Carboxyl transferase domain
    pfam02785
    Location:544 → 651
    Biotin_carb_C; Biotin carboxylase C-terminal domain
    pfam08326
    Location:857 → 1606
    ACC_central; Acetyl-CoA carboxylase, central region
    cl17255
    Location:316 → 507
    ATP-grasp_4; ATP-grasp domain

  3. XM_011953626.1 → XP_011809016.1  acetyl-CoA carboxylase 1 isoform X2

    See identical proteins and their annotated locations for XP_011809016.1

    UniProtKB/TrEMBL
    A0A2K5HV90, A0A2K5HVR2
    Related
    ENSCANP00000008303.1, ENSCANT00000030910.1
    Conserved Domains (5) summary
    COG0439
    Location:118 → 620
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    pfam00364
    Location:753 → 818
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1669 → 2217
    Carboxyl_trans; Carboxyl transferase domain
    pfam08326
    Location:820 → 1562
    ACC_central; Acetyl-CoA carboxylase, central region
    cl27427
    Location:671 → 818
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]

  4. XM_011953629.1 → XP_011809019.1  acetyl-CoA carboxylase 1 isoform X3

    See identical proteins and their annotated locations for XP_011809019.1

    UniProtKB/TrEMBL
    A0A2K5HVR0, A0A2K5HVR2
    Related
    ENSCANP00000008402.1, ENSCANT00000031171.1
    Conserved Domains (5) summary
    COG0439
    Location:60 → 562
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    pfam00364
    Location:695 → 760
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1611 → 2159
    Carboxyl_trans; Carboxyl transferase domain
    pfam08326
    Location:762 → 1504
    ACC_central; Acetyl-CoA carboxylase, central region
    cl27427
    Location:613 → 760
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]
Nucleotide Protein
Heading Accession and Version

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