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ACACA acetyl-CoA carboxylase alpha [ Pteropus vampyrus (large flying fox) ]

Gene ID: 105304993, updated on 30-Mar-2024

Summary

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Gene symbol
ACACA
Gene description
acetyl-CoA carboxylase alpha
Gene type
protein coding
RefSeq status
MODEL
Organism
Pteropus vampyrus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Pteropodinae; Pteropus
Orthologs
human mouse all
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Genomic context

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See ACACA in Genome Data Viewer
Location:
chromosome: Un
Exon count:
58
Annotation release Status Assembly Chr Location
101 current Pvam_2.0 (GCF_000151845.1) Unplaced Scaffold NW_011889139.1 (1397324..1640063)

NW_011889139.1Genomic Context describing neighboring genes Neighboring gene 5S ribosomal RNA Neighboring gene dual specificity phosphatase 14 Neighboring gene 5S ribosomal RNA Neighboring gene transcriptional adaptor 2A Neighboring gene 5S ribosomal RNA Neighboring gene chromosome unknown C17orf78 homolog Neighboring gene mRNA decay activator protein ZFP36L1-like Neighboring gene 5S ribosomal RNA Neighboring gene 5S ribosomal RNA Neighboring gene U4 spliceosomal RNA Neighboring gene apoptosis antagonizing transcription factor Neighboring gene 5S ribosomal RNA Neighboring gene LIM homeobox 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_011889139 Unplaced Scaffold Reference Pvam_2.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables acetyl-CoA carboxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
acetyl-CoA carboxylase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pteropus vampyrus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pvam_2.0

Genomic

  1. NW_011889139.1 Reference Pvam_2.0

    Range
    1397324..1640063
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023522859.1 → XP_023378627.1  acetyl-CoA carboxylase 1 isoform X1

    UniProtKB/TrEMBL
    A0A6P6BU31
    Conserved Domains (4) summary
    COG0439
    Location:155 → 657
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    pfam00364
    Location:790 → 855
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1706 → 2254
    Carboxyl_trans; Carboxyl transferase domain
    pfam08326
    Location:857 → 1599
    ACC_central; Acetyl-CoA carboxylase, central region

  2. XM_023522860.1 → XP_023378628.1  acetyl-CoA carboxylase 1 isoform X2

    UniProtKB/TrEMBL
    A0A6P6BU45
    Conserved Domains (4) summary
    COG0439
    Location:155 → 657
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    pfam00364
    Location:790 → 855
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1698 → 2246
    Carboxyl_trans; Carboxyl transferase domain
    pfam08326
    Location:857 → 1591
    ACC_central; Acetyl-CoA carboxylase, central region

  3. XM_011379399.2 → XP_011377701.1  acetyl-CoA carboxylase 1 isoform X3

    See identical proteins and their annotated locations for XP_011377701.1

    UniProtKB/TrEMBL
    A0A6P3R9L2
    Conserved Domains (7) summary
    COG0439
    Location:118 → 620
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    pfam00289
    Location:118 → 237
    CPSase_L_chain; Carbamoyl-phosphate synthase L chain, N-terminal domain
    pfam00364
    Location:753 → 818
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1669 → 2217
    Carboxyl_trans; Carboxyl transferase domain
    pfam02785
    Location:507 → 614
    Biotin_carb_C; Biotin carboxylase C-terminal domain
    pfam08326
    Location:820 → 1569
    ACC_central; Acetyl-CoA carboxylase, central region
    cl17255
    Location:279 → 470
    ATP-grasp_4; ATP-grasp domain

  4. XM_023522858.1 → XP_023378626.1  acetyl-CoA carboxylase 1 isoform X1

    UniProtKB/TrEMBL
    A0A6P6BU31
    Conserved Domains (4) summary
    COG0439
    Location:155 → 657
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    pfam00364
    Location:790 → 855
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1706 → 2254
    Carboxyl_trans; Carboxyl transferase domain
    pfam08326
    Location:857 → 1599
    ACC_central; Acetyl-CoA carboxylase, central region

  5. XM_011379397.2 → XP_011377699.1  acetyl-CoA carboxylase 1 isoform X3

    See identical proteins and their annotated locations for XP_011377699.1

    UniProtKB/TrEMBL
    A0A6P3R9L2
    Conserved Domains (7) summary
    COG0439
    Location:118 → 620
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    pfam00289
    Location:118 → 237
    CPSase_L_chain; Carbamoyl-phosphate synthase L chain, N-terminal domain
    pfam00364
    Location:753 → 818
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1669 → 2217
    Carboxyl_trans; Carboxyl transferase domain
    pfam02785
    Location:507 → 614
    Biotin_carb_C; Biotin carboxylase C-terminal domain
    pfam08326
    Location:820 → 1569
    ACC_central; Acetyl-CoA carboxylase, central region
    cl17255
    Location:279 → 470
    ATP-grasp_4; ATP-grasp domain

  6. XM_011379396.2 → XP_011377698.1  acetyl-CoA carboxylase 1 isoform X3

    See identical proteins and their annotated locations for XP_011377698.1

    UniProtKB/TrEMBL
    A0A6P3R9L2
    Conserved Domains (7) summary
    COG0439
    Location:118 → 620
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    pfam00289
    Location:118 → 237
    CPSase_L_chain; Carbamoyl-phosphate synthase L chain, N-terminal domain
    pfam00364
    Location:753 → 818
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1669 → 2217
    Carboxyl_trans; Carboxyl transferase domain
    pfam02785
    Location:507 → 614
    Biotin_carb_C; Biotin carboxylase C-terminal domain
    pfam08326
    Location:820 → 1569
    ACC_central; Acetyl-CoA carboxylase, central region
    cl17255
    Location:279 → 470
    ATP-grasp_4; ATP-grasp domain

  7. XM_011379398.2 → XP_011377700.1  acetyl-CoA carboxylase 1 isoform X3

    See identical proteins and their annotated locations for XP_011377700.1

    UniProtKB/TrEMBL
    A0A6P3R9L2
    Conserved Domains (7) summary
    COG0439
    Location:118 → 620
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    pfam00289
    Location:118 → 237
    CPSase_L_chain; Carbamoyl-phosphate synthase L chain, N-terminal domain
    pfam00364
    Location:753 → 818
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1669 → 2217
    Carboxyl_trans; Carboxyl transferase domain
    pfam02785
    Location:507 → 614
    Biotin_carb_C; Biotin carboxylase C-terminal domain
    pfam08326
    Location:820 → 1569
    ACC_central; Acetyl-CoA carboxylase, central region
    cl17255
    Location:279 → 470
    ATP-grasp_4; ATP-grasp domain
Nucleotide Protein
Heading Accession and Version

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