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upf2 UPF2 regulator of nonsense mediated mRNA decay [ Esox lucius (northern pike) ]

Gene ID: 105020176, updated on 12-Sep-2024

Summary

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Gene symbol
upf2
Gene description
UPF2 regulator of nonsense mediated mRNA decay
See related
Ensembl:ENSELUG00000012014
Gene type
protein coding
RefSeq status
MODEL
Organism
Esox lucius
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes; Esocidae; Esox
Orthologs
zebrafish all
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Genomic context

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See upf2 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
25
Annotation release Status Assembly Chr Location
104 current fEsoLuc1.pri (GCF_011004845.1) 23 NC_047591.1 (7507974..7530834)
103 previous assembly Eluc_v4 (GCF_004634155.1) Linkage Group LG23 NC_025990.4 (17838468..17859017, complement)

Chromosome 23 - NC_047591.1Genomic Context describing neighboring genes Neighboring gene transportin 3 Neighboring gene opsin 1 (cone pigments), short-wave-sensitive 1 Neighboring gene calumenin a Neighboring gene proline and serine-rich protein 2 Neighboring gene serine/threonine kinase receptor associated protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of exon-exon junction complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
regulator of nonsense transcripts 2
Names
UPF2 regulator of nonsense transcripts homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Esox lucius Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fEsoLuc1.pri Primary Assembly

Genomic

  1. NC_047591.1 Reference fEsoLuc1.pri Primary Assembly

    Range
    7507974..7530834
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010886946.4 → XP_010885248.2  regulator of nonsense transcripts 2 isoform X1

    UniProtKB/TrEMBL
    A0A3P8Y6Q1
    Conserved Domains (3) summary
    smart00543
    Location:775 → 988
    MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)
    pfam04050
    Location:1121 → 1246
    Upf2; Up-frameshift suppressor 2
    pfam05672
    Location:100 → 189
    MAP7; MAP7 (E-MAP-115) family

  2. XM_020042901.2 → XP_019898460.2  regulator of nonsense transcripts 2 isoform X2

    UniProtKB/TrEMBL
    A0A3P8Y6Q1
    Conserved Domains (3) summary
    smart00543
    Location:775 → 988
    MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)
    pfam04050
    Location:1121 → 1245
    Upf2; Up-frameshift suppressor 2
    pfam05672
    Location:100 → 189
    MAP7; MAP7 (E-MAP-115) family

  3. XM_020042903.2 → XP_019898462.2  regulator of nonsense transcripts 2 isoform X4

    UniProtKB/TrEMBL
    A0A3P8Y6Q1
    Related
    ENSELUP00000011685.3, ENSELUT00000019800.3
    Conserved Domains (3) summary
    smart00543
    Location:775 → 988
    MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)
    pfam04050
    Location:1104 → 1229
    Upf2; Up-frameshift suppressor 2
    pfam05672
    Location:100 → 189
    MAP7; MAP7 (E-MAP-115) family

  4. XM_020042902.2 → XP_019898461.2  regulator of nonsense transcripts 2 isoform X3

    UniProtKB/TrEMBL
    A0A3P8Y6Q1
    Conserved Domains (3) summary
    smart00543
    Location:771 → 984
    MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)
    pfam04050
    Location:1117 → 1242
    Upf2; Up-frameshift suppressor 2
    pfam05672
    Location:100 → 189
    MAP7; MAP7 (E-MAP-115) family

  5. XM_013140118.3 → XP_012995572.2  regulator of nonsense transcripts 2 isoform X5

    UniProtKB/TrEMBL
    A0A3P8Y6Q1
    Related
    ENSELUP00000044071.2, ENSELUT00000061366.2
    Conserved Domains (3) summary
    smart00543
    Location:771 → 984
    MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)
    pfam04050
    Location:1100 → 1225
    Upf2; Up-frameshift suppressor 2
    pfam05672
    Location:100 → 189
    MAP7; MAP7 (E-MAP-115) family

  6. XM_013140119.3 → XP_012995573.2  regulator of nonsense transcripts 2 isoform X6

    UniProtKB/TrEMBL
    A0A3P8Y6Q1
    Related
    ENSELUP00000094659.1, ENSELUT00000096269.1
    Conserved Domains (3) summary
    smart00543
    Location:771 → 984
    MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)
    pfam04050
    Location:1100 → 1224
    Upf2; Up-frameshift suppressor 2
    pfam05672
    Location:100 → 189
    MAP7; MAP7 (E-MAP-115) family

  7. XM_020042904.2 → XP_019898463.2  regulator of nonsense transcripts 2 isoform X7

    UniProtKB/TrEMBL
    A0A6Q2WTJ6
    Conserved Domains (3) summary
    smart00543
    Location:775 → 988
    MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)
    pfam04050
    Location:1121 → 1246
    Upf2; Up-frameshift suppressor 2
    pfam05672
    Location:100 → 189
    MAP7; MAP7 (E-MAP-115) family

  8. XM_010886947.4 → XP_010885249.2  regulator of nonsense transcripts 2 isoform X1

    UniProtKB/TrEMBL
    A0A3P8Y6Q1
    Conserved Domains (3) summary
    smart00543
    Location:775 → 988
    MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)
    pfam04050
    Location:1121 → 1246
    Upf2; Up-frameshift suppressor 2
    pfam05672
    Location:100 → 189
    MAP7; MAP7 (E-MAP-115) family
Nucleotide Protein
Heading Accession and Version

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