Conserved Protein Domain Family
MAP7
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pfam05672: MAP7 (this model, PSSM-Id:398996 is obsolete and has been replaced by 461709)
MAP7 (E-MAP-115) family
The organisation of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilizing protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.
Links
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Statistics
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PSSM-Id: 398996
Aligned: 51 rows
Threshold Bit Score: 39.7079
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_005088298 167 APPVAPSKPMAGTTDREEATRLLAEKRRQAREQRERE-EQERKLQ-AERDKRMREEQLAREAEARAER-EAEARRREEQ- 242  golden hamster
XP_023354711 370 eVGEGKFIAGTTDAEEASKILAEKRRQVRLQKEQEEQ-ERQEREE-RERLEREELERKAEQDRILQEQ-EDRKKEEERKq 446  Tasmanian devil
XP_011961774 403 grASGKPTAGTTDAGEATKILSEKRRQARLQKEQEEQ-ERLEKEK-QDKLEKEELKRKAEEERLRLEE-A-RKQEEEKKq 478  sheep
XP_021404151 486 keESGSKTVAGTTTAEEAAKILTEKRRLAREQRERED-QERIQRQ-EEERIREEEMARRATEEKARRE-EELRKQEEERr 562  Bengalese finch
XP_001342278 315 SPVTPTGK--AGTTDAEEASRLLAERRRLARVLKEQE-EKQRLED-E---RLRVEELQRQQEEERQRQ-EEENRLAEEKr 386  zebrafish
XP_015196643 107 sPVTPTGKPIAGTTDAEEASRLLAERRRQARLQRELE-ERQQREQ-EEAERVRAEEERRKVAEERARQ-EEEARRAEEEr 183  spotted gar
EEN45793     561 pAAPAEDKGKAVLTDEEAAKAALAERRRMVREQREREaELERQRQ-EEEKRRAEEEEKRRLEEEA--RiEEEQRRLAEEy 637  Florida lancelet
EFA11334     347 ENEMTASVTKIRINTEEEAKAALAERRRLAREEAERQaEQERLRI-EMEAQAELE--RQRREEEQIQR-LIEAQRLAEQe 422  red flour beetle
EFN71814     420 vdmSASMIAKIRITTEEEAKAALAERRRLAREQAEREaELERQRQ-EEEARLEAERLRAEEEEQR--RlEEETIRLANEa 496  Florida carpen...
XP_007238974  42 tttsttttkshakpvidgaalrIDEKLRVAKERRE---EQEKQHAaRESQILERERKAKLQVERQ--V-EERQRKLEEQr 115  Mexican tetra

XP_005088298 243 -------------E------AREKAQAeqeeq-----------erlqkQKEEAEARSREEAERQRLEREKHFQKEEQERQ 292  golden hamster
XP_023354711 447 reeeekrkekeeaQkk--amEQQLLKEqqekekqereqqertriekqkEEAEAKAREAAEQMRLEREQIMLQIEQERLVR 524  Tasmanian devil
XP_011961774 479 qeeeekrkvaeeaKqk--akEALLLKEeqekekqekekqekamivkqkEAAEAKAQEAAKQMRLKREQIMLQMEQERLER 556  sheep
XP_021404151 563 vtyeeqqrqaeeeR------VRREQEEqekla-----------elqqqREEAEAKAQEEAERQRLERERIMQQNMQERLE 625  Bengalese finch
XP_001342278 387 lrqeeqrcqremeD------RHQKEQRwkelq-----------ddlerQREEAVQRVHREAERKRQERELLKIQEEQERL 449  zebrafish
XP_015196643 184 lreeeeqrlreeaE------RQQRERQarelq-----------arldrEREEAEARAQQEAERLRQERELQQLQMEQERL 246  spotted gar
EEN45793     638 kkaeeerlrkaieEaekqkrEEEEKQKel-----------------erQREEEERKAREEAEKRQRELEERLAKEEQERQ 700  Florida lancelet
EFA11334     423 rleeairetkrreE--------EERLRreeeq------------rsklLKEEAERKAREEAEKKFAEQQERLKNEEKERE 482  red flour beetle
EFN71814     497 rkaeeqrlqlaieEak--rrEEEDRRKreeea------------rqkqEKEEAERKAREEAEKQRIEMAERLKKEEEERN 562  Florida carpen...
XP_007238974 116 rkeeqrraaveekRk---------------------------------QKQEEEKEHYEAVMRRTLERSNRVEQ------ 156  Mexican tetra

XP_005088298 293 ERRKRLEEIMKRTRKSE-AAETKK 315  golden hamster
XP_023354711 525 KKRIDEIMKRTRKSDVStEVKKEE 548  Tasmanian devil
XP_011961774 557 KKRIDEIMKRTRKSDVSlEVKKED 580  sheep
XP_021404151 626 RKKRIEEIMKRTRKSDQ-NESKlq 648  Bengalese finch
XP_001342278 450 QRKKRIEEIMKRTRKPD--GEKKE 471  zebrafish
XP_015196643 247 QRKKRIEEIMKRTRKSD-TFESKK 269  spotted gar
EEN45793     701 ERKKRLEMIMSRTRKSG-TPGKDK 723  Florida lancelet
EFA11334     483 ARRKRVEAIMRRTRGVN-NANspg 505  red flour beetle
EFN71814     563 ARRKRVEAIMLRTRGRN-QSNTPK 585  Florida carpenter ant
XP_007238974 157 -RQKRwswgglsdadskngesdtg 179  Mexican tetra
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