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pleca plectin a [ Cynoglossus semilaevis (tongue sole) ]

Gene ID: 103393974, updated on 11-Mar-2024

Summary

Gene symbol
pleca
Gene description
plectin a
See related
Ensembl:ENSCSEG00000009105
Gene type
protein coding
RefSeq status
MODEL
Organism
Cynoglossus semilaevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae; Cynoglossinae; Cynoglossus
Orthologs
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Genomic context

See pleca in Genome Data Viewer
Location:
chromosome: 18
Exon count:
48
Annotation release Status Assembly Chr Location
102 current Cse_v1.0 (GCF_000523025.1) 18 NC_024324.1 (2046137..2145292)

Chromosome 18 - NC_024324.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107989945 Neighboring gene eukaryotic translation initiation factor 3, subunit E, b Neighboring gene uncharacterized LOC103393971 Neighboring gene uncharacterized LOC103393979 Neighboring gene epiplakin 1 Neighboring gene uncharacterized LOC103393977 Neighboring gene F-box and leucine-rich repeat protein 6

Genomic regions, transcripts, and products

Genomic Sequence:
NC_024324.1 Chromosome 18 Reference Cse_v1.0 Primary Assembly

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ankyrin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables cadherin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
PubMed 
enables structural constituent of muscle IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in hemidesmosome assembly IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in intermediate filament cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in wound healing IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in hemidesmosome IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in sarcolemma IEA
Inferred from Electronic Annotation
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cynoglossus semilaevis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Cse_v1.0 Primary Assembly

Genomic

  1. NC_024324.1 Reference Cse_v1.0 Primary Assembly

    Range
    2046137..2145292
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025065181.1XP_024920949.1  plectin-like isoform X2

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:29422978
    PLEC; Plectin repeat
    COG5069
    Location:206428
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:797987
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:42134252
    Plectin; Plectin repeat
    cl25732
    Location:11671752
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:14972310
    Neuromodulin_N; Gap junction protein N-terminal region
  2. XM_008331101.3XP_008329323.1  plectin-like isoform X15

    UniProtKB/TrEMBL
    A0A3P8VH09
    Related
    ENSCSEP00000014583.1, ENSCSET00000014758.1
    Conserved Domains (6) summary
    smart00250
    Location:29422978
    PLEC; Plectin repeat
    COG5069
    Location:206428
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:797987
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:42134252
    Plectin; Plectin repeat
    cl25732
    Location:11671752
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:14972310
    Neuromodulin_N; Gap junction protein N-terminal region
  3. XM_025065180.1XP_024920948.1  plectin-like isoform X1

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:29492985
    PLEC; Plectin repeat
    COG5069
    Location:206428
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:797987
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:42204259
    Plectin; Plectin repeat
    cl25732
    Location:11741759
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:15042317
    Neuromodulin_N; Gap junction protein N-terminal region
  4. XM_025065183.1XP_024920951.1  plectin-like isoform X4

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:28892925
    PLEC; Plectin repeat
    COG5069
    Location:146368
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:737927
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:41604199
    Plectin; Plectin repeat
    cl25732
    Location:11141699
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:14442257
    Neuromodulin_N; Gap junction protein N-terminal region
  5. XM_025065182.1XP_024920950.1  plectin-like isoform X3

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:29132949
    PLEC; Plectin repeat
    COG5069
    Location:170392
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:761951
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:41844223
    Plectin; Plectin repeat
    cl25732
    Location:11381723
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:14682281
    Neuromodulin_N; Gap junction protein N-terminal region
  6. XM_025065186.1XP_024920954.1  plectin-like isoform X7

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:27712807
    PLEC; Plectin repeat
    COG5069
    Location:33250
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:619809
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:40424081
    Plectin; Plectin repeat
    cl25732
    Location:9961581
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:13262139
    Neuromodulin_N; Gap junction protein N-terminal region
  7. XM_025065189.1XP_024920957.1  plectin-like isoform X10

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:27582794
    PLEC; Plectin repeat
    COG5069
    Location:20237
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:606796
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:40294068
    Plectin; Plectin repeat
    cl25732
    Location:9831568
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:13132126
    Neuromodulin_N; Gap junction protein N-terminal region
  8. XM_025065187.1XP_024920955.1  plectin-like isoform X8

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:27612797
    PLEC; Plectin repeat
    COG5069
    Location:23240
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:609799
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:40324071
    Plectin; Plectin repeat
    cl25732
    Location:9861571
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:13162129
    Neuromodulin_N; Gap junction protein N-terminal region
  9. XM_025065190.1XP_024920958.1  plectin-like isoform X11

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:27562792
    PLEC; Plectin repeat
    COG5069
    Location:18235
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:604794
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:40274066
    Plectin; Plectin repeat
    cl25732
    Location:9811566
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:13112124
    Neuromodulin_N; Gap junction protein N-terminal region
  10. XM_025065185.1XP_024920953.1  plectin-like isoform X6

    UniProtKB/TrEMBL
    A0A3P8VJ30, A0A3P8VPQ7
    Related
    ENSCSEP00000014342.1, ENSCSET00000014512.1
    Conserved Domains (6) summary
    smart00250
    Location:27772813
    PLEC; Plectin repeat
    COG5069
    Location:33256
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:625815
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:40484087
    Plectin; Plectin repeat
    cl25732
    Location:10021587
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:13322145
    Neuromodulin_N; Gap junction protein N-terminal region
  11. XM_025065188.1XP_024920956.1  plectin-like isoform X9

    UniProtKB/TrEMBL
    A0A3P8VH09, A0A3P8VPW1
    Related
    ENSCSEP00000014495.1, ENSCSET00000014669.1
    Conserved Domains (6) summary
    smart00250
    Location:27602796
    PLEC; Plectin repeat
    COG5069
    Location:17239
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:608798
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:40314070
    Plectin; Plectin repeat
    cl25732
    Location:9851570
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:13152128
    Neuromodulin_N; Gap junction protein N-terminal region
  12. XM_025065191.1XP_024920959.1  plectin-like isoform X12

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:27532789
    PLEC; Plectin repeat
    COG5069
    Location:17239
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:608798
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:40244063
    Plectin; Plectin repeat
    cl25732
    Location:9781563
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:13082121
    Neuromodulin_N; Gap junction protein N-terminal region
  13. XM_025065184.1XP_024920952.1  plectin-like isoform X5

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:27792815
    PLEC; Plectin repeat
    COG5069
    Location:41258
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:627817
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:40504089
    Plectin; Plectin repeat
    cl25732
    Location:10041589
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:13342147
    Neuromodulin_N; Gap junction protein N-terminal region
  14. XM_025065193.1XP_024920961.1  plectin-like isoform X14

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:27722808
    PLEC; Plectin repeat
    COG5069
    Location:41258
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:627817
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:40434082
    Plectin; Plectin repeat
    cl25732
    Location:9971582
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:13272140
    Neuromodulin_N; Gap junction protein N-terminal region
  15. XM_025065192.1XP_024920960.1  plectin-like isoform X13

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:26892725
    PLEC; Plectin repeat
    cd00176
    Location:537727
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:111173
    CH; Calponin homology (CH) domain
    pfam00681
    Location:39603999
    Plectin; Plectin repeat
    cl25732
    Location:9141499
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:12442057
    Neuromodulin_N; Gap junction protein N-terminal region