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pleca plectin a [ Cynoglossus semilaevis (tongue sole) ]

Gene ID: 103393974, updated on 11-Mar-2024

Summary

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Gene symbol
pleca
Gene description
plectin a
See related
Ensembl:ENSCSEG00000009105
Gene type
protein coding
RefSeq status
MODEL
Organism
Cynoglossus semilaevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae; Cynoglossinae; Cynoglossus
Orthologs
zebrafish all
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Genomic context

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See pleca in Genome Data Viewer
Location:
chromosome: 18
Exon count:
48
Annotation release Status Assembly Chr Location
102 current Cse_v1.0 (GCF_000523025.1) 18 NC_024324.1 (2046137..2145292)

Chromosome 18 - NC_024324.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107989945 Neighboring gene eukaryotic translation initiation factor 3, subunit E, b Neighboring gene uncharacterized LOC103393971 Neighboring gene uncharacterized LOC103393979 Neighboring gene epiplakin 1 Neighboring gene uncharacterized LOC103393977 Neighboring gene F-box and leucine-rich repeat protein 6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_024324.1 Chromosome 18 Reference Cse_v1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ankyrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cadherin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables structural constituent of muscle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in hemidesmosome assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intermediate filament cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in wound healing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in hemidesmosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in sarcolemma IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
plectin-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cynoglossus semilaevis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Cse_v1.0 Primary Assembly

Genomic

  1. NC_024324.1 Reference Cse_v1.0 Primary Assembly

    Range
    2046137..2145292
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025065181.1 → XP_024920949.1  plectin-like isoform X2

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:2942 → 2978
    PLEC; Plectin repeat
    COG5069
    Location:206 → 428
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:797 → 987
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4213 → 4252
    Plectin; Plectin repeat
    cl25732
    Location:1167 → 1752
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:1497 → 2310
    Neuromodulin_N; Gap junction protein N-terminal region

  2. XM_008331101.3 → XP_008329323.1  plectin-like isoform X15

    UniProtKB/TrEMBL
    A0A3P8VH09
    Related
    ENSCSEP00000014583.1, ENSCSET00000014758.1
    Conserved Domains (6) summary
    smart00250
    Location:2942 → 2978
    PLEC; Plectin repeat
    COG5069
    Location:206 → 428
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:797 → 987
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4213 → 4252
    Plectin; Plectin repeat
    cl25732
    Location:1167 → 1752
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:1497 → 2310
    Neuromodulin_N; Gap junction protein N-terminal region

  3. XM_025065180.1 → XP_024920948.1  plectin-like isoform X1

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:2949 → 2985
    PLEC; Plectin repeat
    COG5069
    Location:206 → 428
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:797 → 987
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4220 → 4259
    Plectin; Plectin repeat
    cl25732
    Location:1174 → 1759
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:1504 → 2317
    Neuromodulin_N; Gap junction protein N-terminal region

  4. XM_025065183.1 → XP_024920951.1  plectin-like isoform X4

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:2889 → 2925
    PLEC; Plectin repeat
    COG5069
    Location:146 → 368
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:737 → 927
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4160 → 4199
    Plectin; Plectin repeat
    cl25732
    Location:1114 → 1699
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:1444 → 2257
    Neuromodulin_N; Gap junction protein N-terminal region

  5. XM_025065182.1 → XP_024920950.1  plectin-like isoform X3

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:2913 → 2949
    PLEC; Plectin repeat
    COG5069
    Location:170 → 392
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:761 → 951
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4184 → 4223
    Plectin; Plectin repeat
    cl25732
    Location:1138 → 1723
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:1468 → 2281
    Neuromodulin_N; Gap junction protein N-terminal region

  6. XM_025065186.1 → XP_024920954.1  plectin-like isoform X7

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:2771 → 2807
    PLEC; Plectin repeat
    COG5069
    Location:33 → 250
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:619 → 809
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4042 → 4081
    Plectin; Plectin repeat
    cl25732
    Location:996 → 1581
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:1326 → 2139
    Neuromodulin_N; Gap junction protein N-terminal region

  7. XM_025065189.1 → XP_024920957.1  plectin-like isoform X10

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:2758 → 2794
    PLEC; Plectin repeat
    COG5069
    Location:20 → 237
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:606 → 796
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4029 → 4068
    Plectin; Plectin repeat
    cl25732
    Location:983 → 1568
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:1313 → 2126
    Neuromodulin_N; Gap junction protein N-terminal region

  8. XM_025065187.1 → XP_024920955.1  plectin-like isoform X8

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:2761 → 2797
    PLEC; Plectin repeat
    COG5069
    Location:23 → 240
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:609 → 799
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4032 → 4071
    Plectin; Plectin repeat
    cl25732
    Location:986 → 1571
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:1316 → 2129
    Neuromodulin_N; Gap junction protein N-terminal region

  9. XM_025065190.1 → XP_024920958.1  plectin-like isoform X11

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:2756 → 2792
    PLEC; Plectin repeat
    COG5069
    Location:18 → 235
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:604 → 794
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4027 → 4066
    Plectin; Plectin repeat
    cl25732
    Location:981 → 1566
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:1311 → 2124
    Neuromodulin_N; Gap junction protein N-terminal region

  10. XM_025065185.1 → XP_024920953.1  plectin-like isoform X6

    UniProtKB/TrEMBL
    A0A3P8VJ30, A0A3P8VPQ7
    Related
    ENSCSEP00000014342.1, ENSCSET00000014512.1
    Conserved Domains (6) summary
    smart00250
    Location:2777 → 2813
    PLEC; Plectin repeat
    COG5069
    Location:33 → 256
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:625 → 815
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4048 → 4087
    Plectin; Plectin repeat
    cl25732
    Location:1002 → 1587
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:1332 → 2145
    Neuromodulin_N; Gap junction protein N-terminal region

  11. XM_025065188.1 → XP_024920956.1  plectin-like isoform X9

    UniProtKB/TrEMBL
    A0A3P8VH09, A0A3P8VPW1
    Related
    ENSCSEP00000014495.1, ENSCSET00000014669.1
    Conserved Domains (6) summary
    smart00250
    Location:2760 → 2796
    PLEC; Plectin repeat
    COG5069
    Location:17 → 239
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:608 → 798
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4031 → 4070
    Plectin; Plectin repeat
    cl25732
    Location:985 → 1570
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:1315 → 2128
    Neuromodulin_N; Gap junction protein N-terminal region

  12. XM_025065191.1 → XP_024920959.1  plectin-like isoform X12

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:2753 → 2789
    PLEC; Plectin repeat
    COG5069
    Location:17 → 239
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:608 → 798
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4024 → 4063
    Plectin; Plectin repeat
    cl25732
    Location:978 → 1563
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:1308 → 2121
    Neuromodulin_N; Gap junction protein N-terminal region

  13. XM_025065184.1 → XP_024920952.1  plectin-like isoform X5

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:2779 → 2815
    PLEC; Plectin repeat
    COG5069
    Location:41 → 258
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:627 → 817
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4050 → 4089
    Plectin; Plectin repeat
    cl25732
    Location:1004 → 1589
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:1334 → 2147
    Neuromodulin_N; Gap junction protein N-terminal region

  14. XM_025065193.1 → XP_024920961.1  plectin-like isoform X14

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:2772 → 2808
    PLEC; Plectin repeat
    COG5069
    Location:41 → 258
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:627 → 817
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4043 → 4082
    Plectin; Plectin repeat
    cl25732
    Location:997 → 1582
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:1327 → 2140
    Neuromodulin_N; Gap junction protein N-terminal region

  15. XM_025065192.1 → XP_024920960.1  plectin-like isoform X13

    UniProtKB/TrEMBL
    A0A3P8VH09
    Conserved Domains (6) summary
    smart00250
    Location:2689 → 2725
    PLEC; Plectin repeat
    cd00176
    Location:537 → 727
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:111 → 173
    CH; Calponin homology (CH) domain
    pfam00681
    Location:3960 → 3999
    Plectin; Plectin repeat
    cl25732
    Location:914 → 1499
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:1244 → 2057
    Neuromodulin_N; Gap junction protein N-terminal region
Nucleotide Protein
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