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PDIA3 protein disulfide isomerase family A, member 3 [ Latimeria chalumnae (coelacanth) ]

Gene ID: 102357316, updated on 30-Apr-2024

Summary

Gene symbol
PDIA3
Gene description
protein disulfide isomerase family A, member 3
See related
Ensembl:ENSLACG00000013320
Gene type
protein coding
RefSeq status
MODEL
Organism
Latimeria chalumnae
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Coelacanthiformes; Coelacanthidae; Latimeria
Orthologs
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Genomic context

Location:
chromosome: 13
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_04 current fLatCha1.pri (GCF_037176945.1) 13 NC_088151.1 (50082816..50103024, complement)
101 previous assembly LatCha1 (GCF_000225785.1) Unplaced Scaffold NW_005819060.1 (839848..860468)

Chromosome 13 - NC_088151.1Genomic Context describing neighboring genes Neighboring gene small EDRK-rich factor 2-like Neighboring gene RNA polymerase II elongation factor ELL2 Neighboring gene FKBP prolyl isomerase 16 Neighboring gene cation channel sperm-associated protein 2 Neighboring gene zinc transporter ZIP1-like

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein disulfide isomerase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in protein folding IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in response to endoplasmic reticulum stress IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
protein disulfide-isomerase A3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_037176945.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fLatCha1.pri

Genomic

  1. NC_088151.1 Reference fLatCha1.pri

    Range
    50082816..50103024 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005989740.3XP_005989802.1  protein disulfide-isomerase A3

    UniProtKB/TrEMBL
    H3AZR2
    Related
    ENSLACP00000015133.1
    Conserved Domains (5) summary
    cd02995
    Location:368471
    PDI_a_PDI_a'_C; PDIa family, C-terminal TRX domain (a') subfamily; composed of the C-terminal redox active a' domains of PDI, ERp72, ERp57 (or ERp60) and EFP1. PDI, ERp72 and ERp57 are endoplasmic reticulum (ER)-resident eukaryotic proteins involved in oxidative protein ...
    cd03069
    Location:126231
    PDI_b_ERp57; PDIb family, ERp57 subfamily, first redox inactive TRX-like domain b; ERp57 (or ERp60) exhibits both disulfide oxidase and reductase functions like PDI, by catalyzing the formation of disulfide bonds of newly synthesized polypeptides in the ER and acting ...
    cd03073
    Location:235348
    PDI_b'_ERp72_ERp57; PDIb' family, ERp72 and ERp57 subfamily, second redox inactive TRX-like domain b'; ERp72 and ER57 are involved in oxidative protein folding in the ER, like PDI. They exhibit both disulfide oxidase and reductase functions, by catalyzing the formation of ...
    TIGR01130
    Location:19479
    ER_PDI_fam; protein disulfide isomerase, eukaryotic
    cl00388
    Location:25123
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold