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chd4b chromodomain helicase DNA binding protein 4b [ Xiphophorus maculatus (southern platyfish) ]

Gene ID: 102236567, updated on 10-Mar-2024

Summary

Gene symbol
chd4b
Gene description
chromodomain helicase DNA binding protein 4b
See related
Ensembl:ENSXMAG00000011263
Gene type
protein coding
RefSeq status
MODEL
Organism
Xiphophorus maculatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Xiphophorus
Also known as
chd4
Orthologs
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Genomic context

See chd4b in Genome Data Viewer
Location:
chromosome: 3
Exon count:
40
Annotation release Status Assembly Chr Location
102 current X_maculatus-5.0-male (GCF_002775205.1) 3 NC_036445.1 (1638805..1671067, complement)
101 previous assembly Xiphophorus_maculatus-4.4.2 (GCF_000241075.1) Unplaced Scaffold NW_005372208.1 (1393747..1426065)

Chromosome 3 - NC_036445.1Genomic Context describing neighboring genes Neighboring gene lymphotoxin beta receptor Neighboring gene retinol binding protein 1a, cellular Neighboring gene protein tyrosine phosphatase non-receptor type 6 Neighboring gene wingless-type MMTV integration site family, member 4b Neighboring gene cell division cycle 42, like

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables ATP-dependent chromatin remodeler activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables histone binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of NuRD complex IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of chromatin IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
chromodomain-helicase-DNA-binding protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xiphophorus maculatus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference X_maculatus-5.0-male Primary Assembly

Genomic

  1. NC_036445.1 Reference X_maculatus-5.0-male Primary Assembly

    Range
    1638805..1671067 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023330676.1XP_023186444.1  chromodomain-helicase-DNA-binding protein 4 isoform X4

    UniProtKB/TrEMBL
    M4AA75
    Conserved Domains (10) summary
    smart00298
    Location:647700
    CHROMO; Chromatin organization modifier domain
    cd00024
    Location:560599
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd15531
    Location:392434
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:473515
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    pfam06461
    Location:14051540
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:13231372
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:162215
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:17811951
    CHDCT2; CHDCT2 (NUC038) domain
    cl26465
    Location:7491289
    SNF2_N; SNF2 family N-terminal domain
    cl26511
    Location:15241782
    Neuromodulin_N; Gap junction protein N-terminal region
  2. XM_023330674.1XP_023186442.1  chromodomain-helicase-DNA-binding protein 4 isoform X2

    UniProtKB/TrEMBL
    M4AA75
    Conserved Domains (10) summary
    smart00298
    Location:647700
    CHROMO; Chromatin organization modifier domain
    cd00024
    Location:560599
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd15531
    Location:392434
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:473515
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    pfam06461
    Location:14091544
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:13231372
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:162215
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:17851955
    CHDCT2; CHDCT2 (NUC038) domain
    cl26465
    Location:7491289
    SNF2_N; SNF2 family N-terminal domain
    cl26511
    Location:15281786
    Neuromodulin_N; Gap junction protein N-terminal region
  3. XM_023330675.1XP_023186443.1  chromodomain-helicase-DNA-binding protein 4 isoform X3

    UniProtKB/TrEMBL
    M4AA75
    Related
    ENSXMAP00000011369.2, ENSXMAT00000011383.2
    Conserved Domains (10) summary
    smart00298
    Location:647700
    CHROMO; Chromatin organization modifier domain
    cd00024
    Location:560599
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd15531
    Location:392434
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:473515
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    pfam06461
    Location:14061541
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:13241373
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:162215
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:17821952
    CHDCT2; CHDCT2 (NUC038) domain
    cl26465
    Location:7491289
    SNF2_N; SNF2 family N-terminal domain
    cl26511
    Location:15251783
    Neuromodulin_N; Gap junction protein N-terminal region
  4. XM_005798757.3XP_005798814.1  chromodomain-helicase-DNA-binding protein 4 isoform X1

    UniProtKB/TrEMBL
    M4AA75
    Conserved Domains (13) summary
    smart00298
    Location:647700
    CHROMO; Chromatin organization modifier domain
    COG1111
    Location:8941269
    MPH1; ERCC4-related helicase [Replication, recombination and repair]
    cd00024
    Location:560599
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:771929
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd15531
    Location:392434
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:473515
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    pfam00176
    Location:7541050
    SNF2_N; SNF2 family N-terminal domain
    pfam00271
    Location:10741189
    Helicase_C; Helicase conserved C-terminal domain
    pfam06461
    Location:14101545
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:13251373
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:162214
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:17861956
    CHDCT2; CHDCT2 (NUC038) domain
    cl22451
    Location:15901715
    ASF1_hist_chap; ASF1 like histone chaperone