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ago2 argonaute RISC catalytic component 2 [ Xiphophorus maculatus (southern platyfish) ]

Gene ID: 102232716, updated on 10-Mar-2024

Summary

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Gene symbol
ago2
Gene description
argonaute RISC catalytic component 2
See related
Ensembl:ENSXMAG00000000787
Gene type
protein coding
RefSeq status
MODEL
Organism
Xiphophorus maculatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Xiphophorus
Orthologs
human zebrafish all
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Genomic context

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See ago2 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
22
Annotation release Status Assembly Chr Location
102 current X_maculatus-5.0-male (GCF_002775205.1) 13 NC_036455.1 (21261663..21280385, complement)
101 previous assembly Xiphophorus_maculatus-4.4.2 (GCF_000241075.1) Unplaced Scaffold NW_005372261.1 (999587..1009465)

Chromosome 13 - NC_036455.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 221 member A Neighboring gene neuropeptide Y Neighboring gene protein associated with LIN7 2, MAGUK p55 family member b Neighboring gene distal-less homeobox 5a Neighboring gene distal-less homeobox 6a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables endoribonuclease activity, cleaving siRNA-paired mRNA IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulatory ncRNA-mediated gene silencing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of RISC complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein argonaute-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xiphophorus maculatus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference X_maculatus-5.0-male Primary Assembly

Genomic

  1. NC_036455.1 Reference X_maculatus-5.0-male Primary Assembly

    Range
    21261663..21280385 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023344798.1 → XP_023200566.1  protein argonaute-2

    UniProtKB/TrEMBL
    M3ZF21
    Conserved Domains (4) summary
    cd02846
    Location:236 → 356
    PAZ_argonaute_like; PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille. ...
    cd04657
    Location:401 → 826
    Piwi_ago-like; PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the ...
    pfam08699
    Location:187 → 235
    ArgoL1; Argonaute linker 1 domain
    pfam16486
    Location:101 → 175
    ArgoN; N-terminal domain of argonaute

  2. XM_023344796.1 → XP_023200564.1  protein argonaute-2

    UniProtKB/TrEMBL
    M3ZF21
    Related
    ENSXMAP00000000813.1, ENSXMAT00000000816.2
    Conserved Domains (4) summary
    cd02846
    Location:236 → 356
    PAZ_argonaute_like; PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille. ...
    cd04657
    Location:401 → 826
    Piwi_ago-like; PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the ...
    pfam08699
    Location:187 → 235
    ArgoL1; Argonaute linker 1 domain
    pfam16486
    Location:101 → 175
    ArgoN; N-terminal domain of argonaute

RNA

  1. XR_002753669.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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