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PLCB4 phospholipase C beta 4 [ Anas platyrhynchos (mallard) ]

Gene ID: 101805172, updated on 8-Mar-2024

Summary

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Gene symbol
PLCB4
Gene description
phospholipase C beta 4
See related
EnsemblRapid:ENSAPLG00030011356
Gene type
protein coding
RefSeq status
MODEL
Organism
Anas platyrhynchos
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae; Anatinae; Anas
Orthologs
human mouse all
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Genomic context

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See PLCB4 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
44
Annotation release Status Assembly Chr Location
104 current ZJU1.0 (GCF_015476345.1) 3 NC_051774.1 (5682476..5913799)
103 previous assembly IASCAAS_PekingDuck_PBH1.5 (GCF_003850225.1) 3 NC_040048.1 (9507494..9709375)

Chromosome 3 - NC_051774.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119716459 Neighboring gene phospholipase C beta 1 Neighboring gene uncharacterized LOC113843373 Neighboring gene uncharacterized LOC119716458 Neighboring gene uncharacterized LOC110354504 Neighboring gene lysosomal associated membrane protein family member 5 Neighboring gene p21 (RAC1) activated kinase 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Anas platyrhynchos Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ZJU1.0 Primary Assembly

Genomic

  1. NC_051774.1 Reference ZJU1.0 Primary Assembly

    Range
    5682476..5913799
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038177037.1 → XP_038032965.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X5

    UniProtKB/TrEMBL
    A0A8B9T1S7
    Related
    ENSAPLP00030020820.1, ENSAPLT00030030138.1
    Conserved Domains (6) summary
    PTZ00121
    Location:863 → 1177
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:718 → 834
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 684
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:932 → 971
    DUF1154; Protein of unknown function (DUF1154)

  2. XM_038177041.1 → XP_038032969.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X5

    UniProtKB/TrEMBL
    A0A8B9T1S7
    Conserved Domains (6) summary
    PTZ00121
    Location:863 → 1177
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:718 → 834
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 684
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:932 → 971
    DUF1154; Protein of unknown function (DUF1154)

  3. XM_038177035.1 → XP_038032963.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X5

    UniProtKB/TrEMBL
    A0A8B9T1S7
    Conserved Domains (6) summary
    PTZ00121
    Location:863 → 1177
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:718 → 834
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 684
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:932 → 971
    DUF1154; Protein of unknown function (DUF1154)

  4. XM_038177038.1 → XP_038032966.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X5

    UniProtKB/TrEMBL
    A0A8B9T1S7
    Conserved Domains (6) summary
    PTZ00121
    Location:863 → 1177
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:718 → 834
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 684
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:932 → 971
    DUF1154; Protein of unknown function (DUF1154)

  5. XM_038177036.1 → XP_038032964.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X5

    UniProtKB/TrEMBL
    A0A8B9T1S7
    Conserved Domains (6) summary
    PTZ00121
    Location:863 → 1177
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:718 → 834
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 684
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:932 → 971
    DUF1154; Protein of unknown function (DUF1154)

  6. XM_038177034.1 → XP_038032962.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X5

    UniProtKB/TrEMBL
    A0A8B9T1S7
    Related
    ENSAPLP00030020892.1, ENSAPLT00030030273.1
    Conserved Domains (6) summary
    PTZ00121
    Location:863 → 1177
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:718 → 834
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 684
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:932 → 971
    DUF1154; Protein of unknown function (DUF1154)

  7. XM_038177039.1 → XP_038032967.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X5

    UniProtKB/TrEMBL
    A0A8B9T1S7
    Conserved Domains (6) summary
    PTZ00121
    Location:863 → 1177
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:718 → 834
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 684
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:932 → 971
    DUF1154; Protein of unknown function (DUF1154)

  8. XM_038177042.1 → XP_038032970.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X6

    UniProtKB/TrEMBL
    U3J1V3
    Conserved Domains (6) summary
    PTZ00121
    Location:880 → 1197
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:735 → 851
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:329 → 701
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:34 → 160
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:165 → 317
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:949 → 988
    DUF1154; Protein of unknown function (DUF1154)

  9. XM_038177043.1 → XP_038032971.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X9

    UniProtKB/TrEMBL
    A0A8B9T1S7
    Related
    ENSAPLP00030020975.1, ENSAPLT00030030427.1
    Conserved Domains (6) summary
    cd00275
    Location:735 → 851
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:329 → 701
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:34 → 160
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam15921
    Location:886 → 1152
    CCDC158; Coiled-coil domain-containing protein 158
    cd16211
    Location:165 → 317
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:949 → 981
    DUF1154; Protein of unknown function (DUF1154)

  10. XM_013108952.4 → XP_012964406.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X7

    UniProtKB/TrEMBL
    U3J1V3
    Conserved Domains (6) summary
    cd00275
    Location:731 → 847
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:329 → 697
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    PLN02228
    Location:235 → 836
    PLN02228; Phosphoinositide phospholipase C
    cd13361
    Location:34 → 160
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam06631
    Location:945 → 983
    DUF1154; Protein of unknown function (DUF1154)
    pfam09279
    Location:238 → 329
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like

  11. XM_038177032.1 → XP_038032960.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1

    UniProtKB/TrEMBL
    A0A8B9T1S7
    Related
    ENSAPLP00030020754.1, ENSAPLT00030030016.1
    Conserved Domains (6) summary
    PTZ00121
    Location:880 → 1194
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:735 → 851
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:329 → 701
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:34 → 160
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:165 → 317
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:949 → 988
    DUF1154; Protein of unknown function (DUF1154)

  12. XM_038177033.1 → XP_038032961.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X3

    UniProtKB/TrEMBL
    A0A8B9T254
    Conserved Domains (6) summary
    PTZ00121
    Location:868 → 1182
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:723 → 839
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:329 → 689
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:34 → 160
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:165 → 317
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:937 → 976
    DUF1154; Protein of unknown function (DUF1154)

  13. XM_021278923.3 → XP_021134598.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X8

    UniProtKB/TrEMBL
    U3J1V3
    Related
    ENSAPLP00030021040.1, ENSAPLT00030030554.1
    Conserved Domains (7) summary
    cd00275
    Location:719 → 835
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:329 → 685
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:34 → 160
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam06631
    Location:933 → 972
    DUF1154; Protein of unknown function (DUF1154)
    pfam11705
    Location:440 → 542
    RNA_pol_3_Rpc31; DNA-directed RNA polymerase III subunit Rpc31
    cd16211
    Location:165 → 317
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    cl26511
    Location:864 → 1181
    Neuromodulin_N; Gap junction protein N-terminal region

  14. XM_013108930.4 → XP_012964384.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X2

    UniProtKB/TrEMBL
    A0A8B9T1S7
    Related
    ENSAPLP00030020523.1, ENSAPLT00030029580.1
    Conserved Domains (7) summary
    cd00275
    Location:731 → 847
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:329 → 697
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    PLN02228
    Location:235 → 836
    PLN02228; Phosphoinositide phospholipase C
    cd13361
    Location:34 → 160
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam06631
    Location:945 → 983
    DUF1154; Protein of unknown function (DUF1154)
    pfam09279
    Location:238 → 329
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
    pfam09728
    Location:958 → 1195
    Taxilin; Myosin-like coiled-coil protein

  15. XM_013108938.4 → XP_012964392.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X4

    UniProtKB/TrEMBL
    A0A8B9T254
    Related
    ENSAPLP00030020604.1, ENSAPLT00030029738.1
    Conserved Domains (7) summary
    cd00275
    Location:719 → 835
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:329 → 685
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    PLN02228
    Location:235 → 824
    PLN02228; Phosphoinositide phospholipase C
    cd13361
    Location:34 → 160
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam06631
    Location:933 → 971
    DUF1154; Protein of unknown function (DUF1154)
    pfam09279
    Location:238 → 329
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
    pfam09728
    Location:946 → 1183
    Taxilin; Myosin-like coiled-coil protein

RNA

  1. XR_005264526.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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