AGO3 argonaute RISC catalytic component 3 [Oryctolagus cuniculus (rabbit)] - Gene

Summary

Gene symbol: AGO3
Gene description: argonaute RISC catalytic component 3
See related: Ensembl:ENSOCUG00000006255
Gene type: protein coding
RefSeq status: MODEL
Organism: Oryctolagus cuniculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Also known as: EIF2C1
Orthologs: human mouse all
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Genomic context

Location:: chromosome: Un

Exon count:: 24

Annotation release	Status	Assembly	Chr	Location
RS_2023_02	current	UM_NZW_1.0 (GCF_009806435.1)	Unplaced Scaffold	NW_026259156.1 (4283142..4427518)

NW_026259156.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NW_026259156 Unplaced Scaffold Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of stem cell proliferation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulatory ncRNA-mediated gene silencing	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: protein argonaute-3

Names: argonaute 3, RISC catalytic component; eukaryotic translation initiation factor 2C, 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

NW_026259156.1 Reference UM_NZW_1.0 Primary Assembly

Range

4283142..4427518

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_008273686.3 → XP_008271908.1 protein argonaute-3 isoform X1

See identical proteins and their annotated locations for XP_008271908.1

UniProtKB/TrEMBL

G1SQM3

Related

ENSOCUP00000005411.2

Conserved Domains (4) summary

cd02846
Location:228 → 348

PAZ_argonaute_like; PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille. ...

cd04657
Location:393 → 818

Piwi_ago-like; PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the ...

pfam08699
Location:177 → 227

ArgoL1; Argonaute linker 1 domain

pfam16486
Location:73 → 167

ArgoN; N-terminal domain of argonaute
XM_017350208.2 → XP_017205697.1 protein argonaute-3 isoform X5
XM_051832179.1 → XP_051688139.1 protein argonaute-3 isoform X2
XM_051832182.1 → XP_051688142.1 protein argonaute-3 isoform X4
XM_051832185.1 → XP_051688145.1 protein argonaute-3 isoform X6
XM_051832181.1 → XP_051688141.1 protein argonaute-3 isoform X4
XM_051832184.1 → XP_051688144.1 protein argonaute-3 isoform X5
XM_051832180.1 → XP_051688140.1 protein argonaute-3 isoform X3
XM_051832183.1 → XP_051688143.1 protein argonaute-3 isoform X4
XM_051832186.1 → XP_051688146.1 protein argonaute-3 isoform X7