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CHD8 chromodomain helicase DNA binding protein 8 [ Sus scrofa (pig) ]

Gene ID: 100156733, updated on 17-Aug-2024

Summary

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Official Symbol
CHD8provided by VGNC
Official Full Name
chromodomain helicase DNA binding protein 8provided by VGNC
Primary source
VGNC:VGNC:86634
See related
Ensembl:ENSSSCG00000002127
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
CHD8_tv1
Expression
Ubiquitous expression in spleen (RPKM 9.5), ovary (RPKM 9.5) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See CHD8 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
38
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 7 NC_010449.5 (77719476..77780148)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 7 NC_010449.4 (83061334..83121484)

Chromosome 7 - NC_010449.5Genomic Context describing neighboring genes Neighboring gene methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit Neighboring gene TOX high mobility group box family member 4 Neighboring gene RAB2B, member RAS oncogene family Neighboring gene uncharacterized LOC106504487 Neighboring gene SPT16 homolog, facilitates chromatin remodeling subunit Neighboring gene RPGR interacting protein 1 Neighboring gene heterogeneous nuclear ribonucleoprotein C

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP-dependent chromatin remodeler activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
chromodomain-helicase-DNA-binding protein 8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010449.5 Reference Sscrofa11.1 Primary Assembly

    Range
    77719476..77780148
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021099301.1 → XP_020954960.1  chromodomain-helicase-DNA-binding protein 8 isoform X6

    UniProtKB/TrEMBL
    A0A4X1V101, A0A8D0RZ80
    Conserved Domains (5) summary
    smart00592
    Location:2320 → 2360
    BRK; domain in transcription and CHROMO domain helicases
    cd00024
    Location:644 → 704
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:724 → 777
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    pfam10500
    Location:490 → 584
    SR-25; Nuclear RNA-splicing-associated protein
    cl26465
    Location:810 → 1409
    SNF2_N; SNF2 family N-terminal domain

  2. XM_021099294.1 → XP_020954953.1  chromodomain-helicase-DNA-binding protein 8 isoform X1

    UniProtKB/TrEMBL
    A0A8D0RZ80
    Conserved Domains (5) summary
    smart00592
    Location:2368 → 2412
    BRK; domain in transcription and CHROMO domain helicases
    cd00024
    Location:644 → 704
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:724 → 777
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    pfam10500
    Location:490 → 584
    SR-25; Nuclear RNA-splicing-associated protein
    cl26465
    Location:810 → 1409
    SNF2_N; SNF2 family N-terminal domain

  3. XM_021099297.1 → XP_020954956.1  chromodomain-helicase-DNA-binding protein 8 isoform X5

    UniProtKB/TrEMBL
    A0A8D0RZ80
    Conserved Domains (5) summary
    smart00592
    Location:2328 → 2368
    BRK; domain in transcription and CHROMO domain helicases
    cd00024
    Location:644 → 704
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:724 → 777
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    pfam10500
    Location:490 → 584
    SR-25; Nuclear RNA-splicing-associated protein
    cl26465
    Location:810 → 1409
    SNF2_N; SNF2 family N-terminal domain

  4. XM_021099296.1 → XP_020954955.1  chromodomain-helicase-DNA-binding protein 8 isoform X4

    UniProtKB/TrEMBL
    A0A8D0RZ80
    Conserved Domains (5) summary
    smart00592
    Location:2377 → 2417
    BRK; domain in transcription and CHROMO domain helicases
    cd00024
    Location:644 → 704
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:724 → 777
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    pfam10500
    Location:490 → 584
    SR-25; Nuclear RNA-splicing-associated protein
    cl26465
    Location:810 → 1409
    SNF2_N; SNF2 family N-terminal domain

  5. XM_021099298.1 → XP_020954957.1  chromodomain-helicase-DNA-binding protein 8 isoform X6

    UniProtKB/TrEMBL
    A0A4X1V101, A0A8D0RZ80
    Conserved Domains (5) summary
    smart00592
    Location:2320 → 2360
    BRK; domain in transcription and CHROMO domain helicases
    cd00024
    Location:644 → 704
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:724 → 777
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    pfam10500
    Location:490 → 584
    SR-25; Nuclear RNA-splicing-associated protein
    cl26465
    Location:810 → 1409
    SNF2_N; SNF2 family N-terminal domain

  6. XM_013978247.2 → XP_013833701.1  chromodomain-helicase-DNA-binding protein 8 isoform X2

    UniProtKB/TrEMBL
    A0A481CXW3, A0A8D0IS76, A0A8D0RZ80
    Conserved Domains (6) summary
    smart00592
    Location:2319 → 2363
    BRK; domain in transcription and CHROMO domain helicases
    cd00024
    Location:644 → 704
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:830 → 979
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    pfam00176
    Location:814 → 1101
    SNF2_N; SNF2 family N-terminal domain
    pfam00271
    Location:1133 → 1247
    Helicase_C; Helicase conserved C-terminal domain
    pfam00385
    Location:725 → 781
    Chromo; Chromo (CHRromatin Organization MOdifier) domain

  7. XM_021099292.1 → XP_020954951.1  chromodomain-helicase-DNA-binding protein 8 isoform X1

    UniProtKB/TrEMBL
    A0A8D0RZ80
    Conserved Domains (5) summary
    smart00592
    Location:2368 → 2412
    BRK; domain in transcription and CHROMO domain helicases
    cd00024
    Location:644 → 704
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:724 → 777
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    pfam10500
    Location:490 → 584
    SR-25; Nuclear RNA-splicing-associated protein
    cl26465
    Location:810 → 1409
    SNF2_N; SNF2 family N-terminal domain

  8. XM_003482263.4 → XP_003482311.2  chromodomain-helicase-DNA-binding protein 8 isoform X3

    UniProtKB/TrEMBL
    A0A4X1UY74, A0A5K1U8D0, A0A8D0J4L3, A0A8D0RZ80
    Related
    ENSSSCP00000035899.1, ENSSSCT00000056768.2
    Conserved Domains (5) summary
    smart00592
    Location:2311 → 2355
    BRK; domain in transcription and CHROMO domain helicases
    cd00024
    Location:644 → 704
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:724 → 777
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    pfam10500
    Location:490 → 584
    SR-25; Nuclear RNA-splicing-associated protein
    cl26465
    Location:810 → 1409
    SNF2_N; SNF2 family N-terminal domain

  9. XM_021099302.1 → XP_020954961.1  chromodomain-helicase-DNA-binding protein 8 isoform X8

    UniProtKB/TrEMBL
    A0A287BN32
    Related
    ENSSSCP00000057845.2, ENSSSCT00000052517.3
    Conserved Domains (5) summary
    smart00592
    Location:2032 → 2076
    BRK; domain in transcription and CHROMO domain helicases
    cd00024
    Location:365 → 425
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:445 → 498
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    pfam10500
    Location:211 → 305
    SR-25; Nuclear RNA-splicing-associated protein
    cl26465
    Location:531 → 1130
    SNF2_N; SNF2 family N-terminal domain

  10. XM_013978251.2 → XP_013833705.1  chromodomain-helicase-DNA-binding protein 8 isoform X7

    UniProtKB/TrEMBL
    A0A287BN32
    Conserved Domains (6) summary
    smart00592
    Location:2040 → 2084
    BRK; domain in transcription and CHROMO domain helicases
    cd00024
    Location:365 → 425
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:551 → 700
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    pfam00176
    Location:535 → 822
    SNF2_N; SNF2 family N-terminal domain
    pfam00271
    Location:854 → 968
    Helicase_C; Helicase conserved C-terminal domain
    pfam00385
    Location:446 → 502
    Chromo; Chromo (CHRromatin Organization MOdifier) domain

  11. XM_021099300.1 → XP_020954959.1  chromodomain-helicase-DNA-binding protein 8 isoform X6

    UniProtKB/TrEMBL
    A0A4X1V101, A0A8D0RZ80
    Conserved Domains (5) summary
    smart00592
    Location:2320 → 2360
    BRK; domain in transcription and CHROMO domain helicases
    cd00024
    Location:644 → 704
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:724 → 777
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    pfam10500
    Location:490 → 584
    SR-25; Nuclear RNA-splicing-associated protein
    cl26465
    Location:810 → 1409
    SNF2_N; SNF2 family N-terminal domain

  12. XM_021099293.1 → XP_020954952.1  chromodomain-helicase-DNA-binding protein 8 isoform X1

    UniProtKB/TrEMBL
    A0A8D0RZ80
    Conserved Domains (5) summary
    smart00592
    Location:2368 → 2412
    BRK; domain in transcription and CHROMO domain helicases
    cd00024
    Location:644 → 704
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:724 → 777
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    pfam10500
    Location:490 → 584
    SR-25; Nuclear RNA-splicing-associated protein
    cl26465
    Location:810 → 1409
    SNF2_N; SNF2 family N-terminal domain

  13. XM_013978249.2 → XP_013833703.1  chromodomain-helicase-DNA-binding protein 8 isoform X2

    UniProtKB/TrEMBL
    A0A481CXW3, A0A8D0IS76, A0A8D0RZ80
    Conserved Domains (6) summary
    smart00592
    Location:2319 → 2363
    BRK; domain in transcription and CHROMO domain helicases
    cd00024
    Location:644 → 704
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:830 → 979
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    pfam00176
    Location:814 → 1101
    SNF2_N; SNF2 family N-terminal domain
    pfam00271
    Location:1133 → 1247
    Helicase_C; Helicase conserved C-terminal domain
    pfam00385
    Location:725 → 781
    Chromo; Chromo (CHRromatin Organization MOdifier) domain

  14. XM_021099295.1 → XP_020954954.1  chromodomain-helicase-DNA-binding protein 8 isoform X3

    UniProtKB/TrEMBL
    A0A4X1UY74, A0A5K1U8D0, A0A8D0J4L3, A0A8D0RZ80
    Conserved Domains (5) summary
    smart00592
    Location:2311 → 2355
    BRK; domain in transcription and CHROMO domain helicases
    cd00024
    Location:644 → 704
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    pfam00385
    Location:724 → 777
    Chromo; Chromo (CHRromatin Organisation MOdifier) domain
    pfam10500
    Location:490 → 584
    SR-25; Nuclear RNA-splicing-associated protein
    cl26465
    Location:810 → 1409
    SNF2_N; SNF2 family N-terminal domain

  15. XM_013978252.2 → XP_013833706.1  chromodomain-helicase-DNA-binding protein 8 isoform X7

    UniProtKB/TrEMBL
    A0A287BN32
    Conserved Domains (6) summary
    smart00592
    Location:2040 → 2084
    BRK; domain in transcription and CHROMO domain helicases
    cd00024
    Location:365 → 425
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:551 → 700
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    pfam00176
    Location:535 → 822
    SNF2_N; SNF2 family N-terminal domain
    pfam00271
    Location:854 → 968
    Helicase_C; Helicase conserved C-terminal domain
    pfam00385
    Location:446 → 502
    Chromo; Chromo (CHRromatin Organization MOdifier) domain
Nucleotide Protein Strain
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