ACACB acetyl-CoA carboxylase beta [Sus scrofa (pig)] - Gene

Summary

Gene symbol: ACACB
Gene description: acetyl-CoA carboxylase beta
See related: Ensembl:ENSSSCG00000061436
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression: Broad expression in psoas major muscle (RPKM 22.1), heart (RPKM 21.1) and 6 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 54

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	14	NC_010456.5 (41621574..41739916, complement)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	14	NC_010456.4 (44153373..44271216, complement)

Chromosome 14 - NC_010456.5 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables acetyl-CoA carboxylase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables metal ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in fatty acid biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: acetyl-CoA carboxylase 2

NP_001193328.1

EC 6.3.4.14

EC 6.4.1.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001206399.1 → NP_001193328.1 acetyl-CoA carboxylase 2

See identical proteins and their annotated locations for NP_001193328.1

Status: PROVISIONAL

Source sequence(s)

CU329699

UniProtKB/TrEMBL

A0A480EBI4, A0A4X1SU80, A0A8D0NU40

Related

ENSSSCP00000078742.1, ENSSSCT00000095843.1

Conserved Domains (8) summary

COG0439
Location:256 → 759

AccC; Biotin carboxylase [Lipid transport and metabolism]

pfam00289
Location:256 → 375

CPSase_L_chain; Carbamoyl-phosphate synthase L chain, N-terminal domain

pfam00364
Location:893 → 957

Biotin_lipoyl; Biotin-requiring enzyme

pfam01039
Location:1777 → 2324

Carboxyl_trans; Carboxyl transferase domain

pfam02785
Location:646 → 753

Biotin_carb_C; Biotin carboxylase C-terminal domain

pfam08326
Location:958 → 1684

ACC_central; Acetyl-CoA carboxylase, central region

cl17255
Location:416 → 609

ATP-grasp_4; ATP-grasp domain

cl23717
Location:2060 → 2098

crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...