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PLXNA1 plexin A1 [ Ornithorhynchus anatinus (platypus) ]

Gene ID: 100075458, updated on 30-Apr-2024

Summary

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Gene symbol
PLXNA1
Gene description
plexin A1
See related
Ensembl:ENSOANG00000013278
Gene type
protein coding
RefSeq status
MODEL
Organism
Ornithorhynchus anatinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus
Orthologs
human mouse all
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Genomic context

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See PLXNA1 in Genome Data Viewer
Location:
chromosome: X1
Exon count:
33
Annotation release Status Assembly Chr Location
105 current mOrnAna1.pri.v4 (GCF_004115215.2) X1 NC_041749.1 (87984871..88228259, complement)

Chromosome X1 - NC_041749.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114806300 Neighboring gene small nucleolar RNA SNORA7 Neighboring gene small nucleolar RNA SNORA7 Neighboring gene small nucleolar RNA SNORA7 Neighboring gene transfer RNA lysine (anticodon CUU) Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 6 Neighboring gene transmembrane protein adipocyte associated 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_041749.1 Chromosome X1 Reference mOrnAna1.pri.v4 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables semaphorin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of axonogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell shape IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in semaphorin-plexin signaling pathway involved in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of semaphorin receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
plexin-A1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ornithorhynchus anatinus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrnAna1.pri.v4 Primary Assembly

Genomic

  1. NC_041749.1 Reference mOrnAna1.pri.v4 Primary Assembly

    Range
    87984871..88228259 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029050206.2 → XP_028906039.1  plexin-A1 isoform X2

    UniProtKB/TrEMBL
    A0A6I8NJA4, F6T081
    Related
    ENSOANP00000020965.3
    Conserved Domains (9) summary
    cd11271
    Location:30 → 503
    Sema_plexin_A1; The Sema domain, a protein interacting module, of Plexin A1
    smart00423
    Location:799 → 844
    PSI; domain found in Plexins, Semaphorins and Integrins
    cd01179
    Location:950 → 1035
    IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    cd01180
    Location:853 → 949
    IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    cd01181
    Location:1037 → 1137
    IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    pfam01833
    Location:1139 → 1223
    TIG; IPT/TIG domain
    pfam05283
    Location:651 → 727
    MGC-24; Multi-glycosylated core protein 24 (MGC-24), sialomucin
    pfam01437
    Location:504 → 546
    PSI; Plexin repeat
    pfam08337
    Location:1307 → 1855
    Plexin_cytopl; Plexin cytoplasmic RasGAP domain

  2. XM_029050204.2 → XP_028906037.1  plexin-A1 isoform X1

    UniProtKB/TrEMBL
    A0A6I8NJA4
    Conserved Domains (9) summary
    cd11271
    Location:30 → 503
    Sema_plexin_A1; The Sema domain, a protein interacting module, of Plexin A1
    smart00423
    Location:799 → 844
    PSI; domain found in Plexins, Semaphorins and Integrins
    cd01179
    Location:950 → 1035
    IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    cd01180
    Location:853 → 949
    IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    cd01181
    Location:1037 → 1137
    IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    pfam01833
    Location:1139 → 1223
    TIG; IPT/TIG domain
    pfam05283
    Location:651 → 727
    MGC-24; Multi-glycosylated core protein 24 (MGC-24), sialomucin
    pfam01437
    Location:504 → 546
    PSI; Plexin repeat
    pfam08337
    Location:1307 → 1856
    Plexin_cytopl; Plexin cytoplasmic RasGAP domain

  3. XM_029050202.2 → XP_028906035.1  plexin-A1 isoform X1

    UniProtKB/TrEMBL
    A0A6I8NJA4
    Conserved Domains (9) summary
    cd11271
    Location:30 → 503
    Sema_plexin_A1; The Sema domain, a protein interacting module, of Plexin A1
    smart00423
    Location:799 → 844
    PSI; domain found in Plexins, Semaphorins and Integrins
    cd01179
    Location:950 → 1035
    IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    cd01180
    Location:853 → 949
    IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    cd01181
    Location:1037 → 1137
    IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    pfam01833
    Location:1139 → 1223
    TIG; IPT/TIG domain
    pfam05283
    Location:651 → 727
    MGC-24; Multi-glycosylated core protein 24 (MGC-24), sialomucin
    pfam01437
    Location:504 → 546
    PSI; Plexin repeat
    pfam08337
    Location:1307 → 1856
    Plexin_cytopl; Plexin cytoplasmic RasGAP domain

  4. XM_039910099.1 → XP_039766033.1  plexin-A1 isoform X3

    UniProtKB/TrEMBL
    A0A6I8NJA4
    Conserved Domains (9) summary
    cd11271
    Location:30 → 503
    Sema_plexin_A1; The Sema domain, a protein interacting module, of Plexin A1
    cd01179
    Location:950 → 1035
    IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    cd01180
    Location:853 → 949
    IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    cd01181
    Location:1037 → 1137
    IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    pfam01437
    Location:504 → 546
    PSI; Plexin repeat
    pfam01833
    Location:1139 → 1223
    TIG; IPT/TIG domain
    pfam08337
    Location:1307 → 1679
    Plexin_cytopl; Plexin cytoplasmic RasGAP domain
    pfam17960
    Location:559 → 649
    TIG_plexin; TIG domain
    pfam18020
    Location:703 → 797
    TIG_2; TIG domain found in plexin
Nucleotide Protein
Heading Accession and Version

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