U.S. flag

An official website of the United States government

Format
Items per page
Sort by

Send to:

Choose Destination

Search results

Items: 1 to 20 of 653

1.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Quercus alba; Trypanosoma cruzi; Bothrops moojeni; Pachymenia carnosa; Rhodotorula; Bos taurus; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius; Gallus gallus; Oryctolagus cuniculus; Mus musculus; Human immunodeficiency virus 1; unidentified; Megathura crenulata; Gossypium hirsutum; Pandalus borealis; Oncorhynchus nerka; Homo sapiens; Sus scrofa domesticus
Type:
Protein profiling by protein array
Platforms:
GPL23565 GPL23566
55 Samples
Download data: GPR
Series
Accession:
GSE100438
ID:
200100438
2.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies VII

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...
Organism:
Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Mus musculus; Human immunodeficiency virus 1; Trypanosoma cruzi; Gallus gallus; Pachymenia carnosa; Quercus alba; Pandalus borealis; Oncorhynchus nerka; Sus scrofa domesticus; Ceratonia siliqua; Bothrops moojeni; Senegalia senegal; Dermestes lardarius; Ovis aries; Oryctolagus cuniculus; Megathura crenulata; Frangula alnus
Type:
Protein profiling by protein array
Platform:
GPL23566
7 Samples
Download data: GPR, TXT
Series
Accession:
GSE100310
ID:
200100310
3.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies VI

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...
Organism:
Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Mus musculus; Human immunodeficiency virus 1; Quercus alba; Oryctolagus cuniculus; Megathura crenulata; Pandalus borealis; Oncorhynchus nerka; Sus scrofa domesticus; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius; Trypanosoma cruzi; Gallus gallus; Bothrops moojeni; Pachymenia carnosa
Type:
Protein profiling by protein array
Platform:
GPL23566
7 Samples
Download data: GPR, TXT
Series
Accession:
GSE100309
ID:
200100309
4.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies V

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...
Organism:
Rhodotorula; Trypanosoma cruzi; Gallus gallus; Mus musculus; Human immunodeficiency virus 1; Homo sapiens; Bos taurus; Bothrops moojeni; Pachymenia carnosa; Pandalus borealis; Oncorhynchus nerka; Sus scrofa domesticus; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius; Quercus alba; Gossypium hirsutum; Oryctolagus cuniculus; Megathura crenulata
Type:
Protein profiling by protein array
Platform:
GPL23566
7 Samples
Download data: GPR, TXT
Series
Accession:
GSE100308
ID:
200100308
5.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies IV

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...
Organism:
Quercus alba; Gossypium hirsutum; Pandalus borealis; Oncorhynchus nerka; Homo sapiens; Trypanosoma cruzi; Bos taurus; Gallus gallus; Sus scrofa domesticus; Ovis aries; Oryctolagus cuniculus; Ceratonia siliqua; Megathura crenulata; Frangula alnus; Rhodotorula; Mus musculus; Human immunodeficiency virus 1; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa; Dermestes lardarius
Type:
Protein profiling by protein array
Platform:
GPL23566
7 Samples
Download data: GPR, TXT
Series
Accession:
GSE100307
ID:
200100307
6.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies III

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...
Organism:
Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Trypanosoma cruzi; Gallus gallus; Mus musculus; Human immunodeficiency virus 1; Bothrops moojeni; Pachymenia carnosa; Pandalus borealis; Oncorhynchus nerka; Sus scrofa domesticus; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius; Quercus alba; Oryctolagus cuniculus; Megathura crenulata
Type:
Protein profiling by protein array
Platform:
GPL23566
7 Samples
Download data: GPR, TXT
Series
Accession:
GSE99874
ID:
200099874
7.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies II

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...
Organism:
Homo sapiens; Bos taurus; Quercus alba; Gossypium hirsutum; Oncorhynchus nerka; Pandalus borealis; Gallus gallus; Sus scrofa domesticus; Ovis aries; Oryctolagus cuniculus; Ceratonia siliqua; Megathura crenulata; Frangula alnus; Dermestes lardarius; Rhodotorula; Trypanosoma cruzi; Mus musculus; Human immunodeficiency virus 1; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa
Type:
Protein profiling by protein array
Platform:
GPL23566
14 Samples
Download data: GPR, TXT
Series
Accession:
GSE99873
ID:
200099873
8.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies I

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...
Organism:
Trypanosoma cruzi; Rhodotorula; Bos taurus; Mus musculus; Human immunodeficiency virus 1; Ceratonia siliqua; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa; Dermestes lardarius; Gallus gallus; Ovis aries; Oryctolagus cuniculus; unidentified; Megathura crenulata; Frangula alnus; Quercus alba; Gossypium hirsutum; Pandalus borealis; Oncorhynchus nerka; Homo sapiens; Sus scrofa domesticus
Type:
Protein profiling by protein array
Platform:
GPL23565
6 Samples
Download data: GPR, TXT
Series
Accession:
GSE99872
ID:
200099872
9.

Whole-Cell Cancer Vaccines Induce Large Antibody Responses to Carbohydrates and Glycoproteins

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to profile anti-glycan immune responses to whole-cell vaccines: GVAX Pancreas, K562-GM and H1299. The aim was to indentify anti-glycan antibody responses relevent to patient clinical outcomes Results: Immune responses to non-human antigens bovine fetuin and alpha-Gal antigens were identified induced by GVAX Pancreas. The magnitude of these responses inversely correlate with patient survival. more...
Organism:
Trypanosoma cruzi; Gallus gallus; Bothrops moojeni; Pachymenia carnosa; Pandalus borealis; Oncorhynchus nerka; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius; Gossypium hirsutum; Homo sapiens; Bos taurus; Mus musculus; Human immunodeficiency virus 1; Quercus alba; Oryctolagus cuniculus; Megathura crenulata
Type:
Other
Platform:
GPL21991
168 Samples
Download data: GPR, TXT
Series
Accession:
GSE83087
ID:
200083087
10.

A Simple, Inexpensive Strategy for Predicting Potential Beneficial Clinical Responses on Prostate Cancer Vaccine Therapy

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Quercus alba; Megathura crenulata; Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Mus musculus; Pandalus borealis; Oncorhynchus nerka; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius; Trypanosoma cruzi; Gallus gallus; Bothrops moojeni; Pachymenia carnosa
Type:
Other
Platforms:
GPL20117 GPL20116
331 Samples
Download data
Series
Accession:
GSE68405
ID:
200068405
11.

Development of a glycan microarray based method for ABO blood typing

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to develop a novel method to assign ABO blood type. The method will then be applied to samples from patients treated with PROSTVAC to determine if blood type correlates with survival Results: Many blood group A and B antigens correlate with blood type. Blood typing is best achieved using a combination of 10 signals Conclusion: ABO blood type can be determined with greater than 97% accuracy using only 4 microliters of serum.
Organism:
Quercus alba; Gossypium hirsutum; Pandalus borealis; Oncorhynchus nerka; Homo sapiens; Trypanosoma cruzi; Bos taurus; Gallus gallus; Ovis aries; Ceratonia siliqua; Megathura crenulata; Frangula alnus; Rhodotorula; Mus musculus; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa; Dermestes lardarius
Type:
Other
Platform:
GPL20116
220 Samples
Download data: TXT
Series
Accession:
GSE68403
ID:
200068403
12.

Infectious hematopoietic necrosis virus (IHNV) persistence in Sockeye Salmon: effect on brain transcriptome and response to the viral mimic poly(I:C)

(Submitter supplied) To characterise the transcriptional response in brain of Sockeye Salmon (Oncorhynchus nerka) that were persistently infected with infectious hematopoietic necrosis virus (IHNV) and to determine whether carrying the IHNV affects the ability to respond to other immunological challenges we compared the brain transcriptome of IHNV carriers, IHNV-negative survivors, and naïve Sockeye Salmon that were never exposed to IHNV. more...
Organism:
Oncorhynchus nerka; Salmo salar
Type:
Expression profiling by array
Platform:
GPL11299
35 Samples
Download data: TXT
Series
Accession:
GSE65241
ID:
200065241
13.

Facing warm temperatures during migration – cardiac mRNA responses of two adult sockeye salmon Oncorhynchus nerka populations to warming and swimming challenges

(Submitter supplied) The main findings of the current study were that exposing adult sockeye salmon Oncorhynchus nerka to a warm temperature that they regularly encounter during their river migration induced an mRNA-level heat shock response that is exacerbated with swimming. Similar immune defense-related responses were also observed. Microarray analyses revealed that 347 genes were differentially expressed between the cold (12-13° C) and warm (18-19° C) treated fish (P < 0.01), with stress response (GO:0006950; P = 0.014) and response to fungus (GO:0009620; P = 0.003) elevated with warm treatment, while expression for genes involved in oxidative phosphorylation (GO:0006119; P = 0.0019) and electron transport chain (GO:0022900; P = 0.00043) increased in cold-treated fish. more...
Organism:
Salmo salar; Oncorhynchus nerka; Oncorhynchus mykiss
Type:
Expression profiling by array
Platform:
GPL3976
8 Samples
Download data: TXT
Series
Accession:
GSE50054
ID:
200050054
14.

Transcriptomic responses to high water temperature in Pacific salmon

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Oncorhynchus nerka; Oncorhynchus gorbuscha; Salmo salar
Type:
Expression profiling by array
Platform:
GPL11299
98 Samples
Download data: TXT
Series
Accession:
GSE42558
ID:
200042558
15.

Transcriptomic responses to high water temperature in Pacific salmon [2009]

(Submitter supplied) Characterizing a common cellular stress response (CSR) to high water temperature across species and populations is necessary for identifying the capacity of Pacific salmon (Oncorhynchus spp.) to persist in current and future climate warming scenarios, especially for populations at the southern periphery of their species' distributions. In this study, populations of wild adult pink (O. gorbuscha) and sockeye (O. more...
Organism:
Salmo salar; Oncorhynchus gorbuscha; Oncorhynchus nerka
Type:
Expression profiling by array
Platform:
GPL11299
44 Samples
Download data: TXT
Series
Accession:
GSE42557
ID:
200042557
16.

Transcriptomic responses to high water temperature in Pacific salmon [2008]

(Submitter supplied) Characterizing a common cellular stress response (CSR) to high water temperature across species and populations is necessary for identifying the capacity of Pacific salmon (Oncorhynchus spp.) to persist in current and future climate warming scenarios, especially for populations at the southern periphery of their species' distributions. In this study, populations of wild adult pink (O. gorbuscha) and sockeye (O. more...
Organism:
Oncorhynchus nerka; Oncorhynchus gorbuscha; Salmo salar
Type:
Expression profiling by array
Platform:
GPL11299
33 Samples
Download data: TXT
Series
Accession:
GSE42556
ID:
200042556
17.

Transcriptomic responses to high water temperature in Pacific salmon [2007]

(Submitter supplied) Characterizing a common cellular stress response (CSR) to high water temperature across species and populations is necessary for identifying the capacity of Pacific salmon (Oncorhynchus spp.) to persist in current and future climate warming scenarios, especially for populations at the southern periphery of their species' distributions. In this study, populations of wild adult pink (O. gorbuscha) and sockeye (O. more...
Organism:
Oncorhynchus gorbuscha; Salmo salar; Oncorhynchus nerka
Type:
Expression profiling by array
Platform:
GPL11299
21 Samples
Download data: TXT
Series
Accession:
GSE42555
ID:
200042555
18.

Sockeye salmon (Oncorhynchus nerka) from Aniakchak National Monument and Preserve muscle transcriptome

(Submitter supplied) This dataset was gene expression from natural sockeye salmon populations used to test the preservation of coexpression networks that were found in lake whitefish. Here is the abstract of the manuscript:Background : A functional understanding of processes involved in adaptive divergence is one of the awaiting opportunities afforded by high throughput transcriptomic technologies. Functional analysis of co-expressed genes has succeeded in the biomedical field in identifying key drivers of disease pathways. more...
Organism:
Oncorhynchus nerka; Salmo salar
Type:
Expression profiling by array
Platform:
GPL6260
49 Samples
Download data: TXT
Series
Accession:
GSE42985
ID:
200042985
19.

Consequences of high temperatures and premature mortality on the transcriptome and blood physiology of wild adult sockeye salmon (Oncorhynchus nerka)

(Submitter supplied) We collected sockeye salmon from the Fraser River, British Columbia, and held them at ecologically relevant temperatures (14C and 19C) determine the effect of elevated water temperature on cellular processes in non-lethally sampled gill tissue and blood plasma over a period of seven days that represents a significant portion of their upstream migration. Time-matched fish that died prematurely over the course of the holding study were also sampled for gill tissue and the transcriptomic responses in moribund fish were compared with surviving fish. more...
Organism:
Oncorhynchus mykiss; Oncorhynchus nerka; Salmo salar; Oncorhynchus tshawytscha; Coregonus clupeaformis; Osmerus mordax
Type:
Expression profiling by array
Platform:
GPL2716
40 Samples
Download data: TXT
Series
Accession:
GSE33586
ID:
200033586
20.

Ecological transcriptomics of lake-type and riverine sockeye salmon (Oncorhynchus nerka) muscle tissue

(Submitter supplied) We sampled lake-type and riverine sockeye in the pristine natural habitats of Aniakchak National Monument and Preserve, Alaska USA.
Organism:
Oncorhynchus nerka; Salmo salar
Type:
Expression profiling by array
Platform:
GPL6260
30 Samples
Download data: TXT
Series
Accession:
GSE31214
ID:
200031214
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=txid8023[Organism]|query=1|qty=29|blobid=MCID_670a927cc7d3ca20d5788753|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center