GEO DataSets

(Submitter supplied) Cleavage and polyadenylation are the final steps of eukaryotic mRNA 3' end formation. The most critical element in humans and other model organisms is the poly(A) signal, an AAUAAA hexamer. We recently discovered that the deeply branching eukaryote – Giardia lamblia uses a different but well-defined poly(A) signal, AGURAA. To better characterize when this evolutionary shift in the poly(A) signal occurred, we performed direct RNA sequencing of four protists within the Metamonada supergroup and two outgroup protists. more...

Organism:

Giardia muris; Entamoeba histolytica; Naegleria gruberi; Trichomonas vaginalis; Tritrichomonas foetus; Giardia intestinalis

Type:

Expression profiling by high throughput sequencing

6 related Platforms

20 Samples

Download data: TSV

(Submitter supplied) Naegleria gruberi is a single-celled eukaryote best known for its remarkable ability to form an entire microtubule cytoskeleton de novo during its metamorphosis from an amoeba into a flagellate, including two basal bodies (equivalent to centrioles), two flagella (equivalent to cilia), and a cytoplasmic microtubule array. This full-genome transcriptional analysis, performed at 20-minute intervals throughout Naegleria differentiation, reveals vast transcriptional changes, including the differential expression of cytoskeletal, metabolism, signaling and stress response genes. more...

Organism:

Naegleria gruberi

Type:

Expression profiling by array

Platform:

GPL10359

15 Samples

Download data: PAIR

(Submitter supplied) NimbleGen design name 080519_N_gruberi_UCBerk_LFL_expr, NimbleGen design ID 2451. Array consists of 182,813 probes corresponding to 15,777 gene models predicted on the N.gruberi genome sequence version 1.0 (http://genome.jgi-psf.org/Naegr1/Naegr1.home.html), and an additional 963 orfs identified in intergenic regions (these orf ids can also be accessed via http://genome.jgi-psf.org/Naegr1/Naegr1.home.html). more...

Organism:

Naegleria gruberi

1 Series

15 Samples

Download data: NDF, NGD