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Items: 1 to 20 of 1540

1.

Listeria monocytogenes transcriptional response to low concentrations of paracetic acid (PAA)

(Submitter supplied) Peracetic acid (PAA), a strong oxidizing agent, has been widely used as a disinfectant in food processing settings as it does not produce harmful chlorinated by-products. In the present study, the transcriptional response of Listeria monocytogenes to 2.5 ppm of PAA was assessed using RNA-sequencing (RNA-seq). Our analysis revealed 12 differentially expressed genes, of which 9 were up-regulated (ohrR, ohrA, rpsN, lmo0637, lmo1973, fur, lmo2492, zurM, and lmo1007), and 3 were down-regulated (argG, lmo0604, lmo2156) in PAA treated samples compared to the control samples. more...
Organism:
Listeria monocytogenes
Type:
Expression profiling by high throughput sequencing
Platform:
GPL27107
18 Samples
Download data: TAB
Series
Accession:
GSE269393
ID:
200269393
2.

Untargeted and targeted transcriptome analysis to decipher the impact of exogenous fatty acids in cold stress adaptation of Listeria monocytogenes

(Submitter supplied) Listeria monocytogenes is a ubiquitous and psychrophilic foodborne pathogen commonly found in raw materials, ready to eat products and food environments. It was previously demonstrated that L. monocytogenes can grow faster at low temperature when unsaturated fatty acids (UFA) are present in its environment. In this study, we used comparative gene expression profiling of RNA-sequencing data to understand the impact of UFA on the behavior and cold adaptation of L. more...
Organism:
Listeria monocytogenes
Type:
Expression profiling by high throughput sequencing
Platform:
GPL26477
12 Samples
Download data: TXT
Series
Accession:
GSE268246
ID:
200268246
3.

Deep starvation induces loss of cell wall and dormancy in Listeria

(Submitter supplied) Bacteria have developed multiple strategies, such as sporulation, to cope with environmental stress. Non-sporulating bacteria, however, may “hibernate” into a so-called viable but non-culturable (VBNC) state, where they are no longer able to grow in standard culture media and thus become undetectable by conventional growth-based methods. VBNC pathogens pose a significant risk for human and animal health as they can “wake up” back into a vegetative and virulent state. more...
Organism:
Listeria monocytogenes EGD-e
Type:
Expression profiling by high throughput sequencing
Platform:
GPL33865
6 Samples
Download data: TSV
Series
Accession:
GSE246157
ID:
200246157
4.

Catabolite control protein C (CcpC) contributes to virulence and hydrogen peroxide-induced oxidative stress responses in Listeria monocytogenes

(Submitter supplied) Listeria monocytogenes causes listeriosis, an infectious and potentially fatal disease of animals and humans. A diverse network of transcriptional regulators, including LysR-type catabolite control protein C (CcpC), is critical for the survival of L. monocytogenes and its ability to transition into the host environment. In this study, we explored the physiological and genetic consequences of deleting ccpC and the effects of such deletion on the ability of L. more...
Organism:
Listeria monocytogenes serotype 4b str. F2365
Type:
Expression profiling by high throughput sequencing
Platform:
GPL34483
9 Samples
Download data: TXT
Series
Accession:
GSE267669
ID:
200267669
5.

Microscopic and transcriptomic characterization of Listeria monocytogenes aggregation and biofilm formation on stainless steel surfaces in the presence of cantaloupe juice extract

(Submitter supplied) Listeria monocytogenes (Lm) cells can attach to both cantaloupe surface and food contact surfaces and promote biofilm growth. This study was to understand the impact of cantaloupe juice on the physiology and transcriptome of Lm planktonic cells and biofilm cells grown on stainless steel coupons using confocal laser scanning microscopy (CLSM), Cryo-Scanning Electron Microscopy (Cryo-SEM) and RNA Seq technology. more...
Organism:
Listeria monocytogenes
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL33772 GPL26477
30 Samples
Download data: SF
Series
Accession:
GSE243459
ID:
200243459
6.

Contrasting genes conferring short and long-term biofilm adaptation in Listeria

(Submitter supplied) Listeria monocytogenes is an opportunistic food-borne bacterium that is capable of infecting humans with high rates of hospitalisation and mortality. Natural populations are genotypically and phenotypically variable, with some lineages being responsible for most human infections. The success of L. monocytogenes is linked to its capacity to persist on food and in the environment. Biofilms are an important feature that allow these bacteria to persist and infect humans, therefore, understanding the genetic basis of biofilm formation is key to understanding transmission. more...
Organism:
Listeria monocytogenes
Type:
Expression profiling by high throughput sequencing
Platform:
GPL33536
16 Samples
Download data: CSV, XLSX
Series
Accession:
GSE235979
ID:
200235979
7.

The RNA-binding protein PNPase regulates biofilm formation and virulence in Listeria monocytogenes

(Submitter supplied) Biofilm-related diseases are typically persistent infections, and a challenge for medical treatment. Biofilms are communities of bacteria that attach to surfaces and are enclosed in an extracellular matrix. These sessile microorganisms can endure external stresses like nutrient deprivation, antibiotic treatments, and immune defences. Therefore, biofilms create conditions favourable for bacterial pathogenesis. more...
Organism:
Listeria monocytogenes
Type:
Expression profiling by high throughput sequencing
Platform:
GPL32523
4 Samples
Download data: TXT
Series
Accession:
GSE210097
ID:
200210097
8.

RNA degradation analysis reveals ribosome dynamics in complex microbiome samples

(Submitter supplied) The microbiome has revealed itself as a key player in health and disease. To better understand its role, in addition to microbial diversity, it is important to understand species-specific activity and gene expression. While metatranscriptomics investigates mRNA abundance2, it does not inform about faster post-transcriptional regulation3. Although prokaryotic translation is a common target for antibiotics, a direct measurement of microbiome ribosome dynamics remains inaccessible. more...
Organism:
Escherichia coli; Synechocystis sp. PCC 6803; Staphylococcus aureus; Bacillus amyloliquefaciens; Lactiplantibacillus plantarum; Cryptococcus neoformans; Caulobacter vibrioides; Enterococcus faecalis; Bacillus subtilis; Limosilactobacillus reuteri; Limosilactobacillus fermentum; human feces metagenome; Segatella copri; Alistipes finegoldii; Hoylesella timonensis; compost metagenome; Listeria monocytogenes; Saccharomyces cerevisiae; Salmonella enterica; Parabacteroides merdae
Type:
Other
17 related Platforms
199 Samples
Download data: BEDGRAPH, TXT, XLSX
Series
Accession:
GSE153497
ID:
200153497
9.

Analysis of Listeria monocytogenes

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Listeria monocytogenes
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17257
11 Samples
Download data
Series
Accession:
GSE103754
ID:
200103754
10.

Analysis of Listeria monocytogenes response to bacitracin

(Submitter supplied) we report that bacitracin is the signal that triggers the induction of VirR, its operon and its regulon
Organism:
Listeria monocytogenes
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17257
5 Samples
Download data: TXT
Series
Accession:
GSE103752
ID:
200103752
11.

Analysis of Listeria monocytogenes VirR regulon

(Submitter supplied) by comparing WT strain vs a delta-VirR strain, we complete the analysis of VirR regulon, and we show that virR induces the expression of a small RNA
Organism:
Listeria monocytogenes
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17257
6 Samples
Download data: TXT
Series
Accession:
GSE103751
ID:
200103751
12.

Transcriptomic analysis of biofilm formation in persistent and transient Listeria monocytogenes from the retail deli environment

(Submitter supplied) Persistence of Listeria monocytogenes in retail deli environments is a serious food safety issue, potentially leading to cross-contamination of ready-to-eat foods such as deli meats, salads, and cheeses. We previously discovered strong evidence of L. monocytogenes persistence in delis across multiple states. We hypothesized that this was correlated with isolates’ innate characteristics, such as biofilm-forming capacity or gene differences.We further chose four isolates for RNA-sequencing analysis and compared their global biofilm transcriptome to their global planktonic transcriptome. more...
Organism:
Listeria monocytogenes; Listeria innocua
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL21330 GPL30260
30 Samples
Download data: TXT
Series
Accession:
GSE176617
ID:
200176617
13.

RNA Atlas of Bacterial Human Pathogens Uncovers Stress Dynamics Linked to Bacterial Infections

(Submitter supplied) Pathogenic bacteria encounter a variety of stressful host environments during infection. Their responses to meet these challenges protect them from deadly damages and aid in adaption to harmful environments. Bacterial products critical for this protection are therefore interesting as suitable targets for new antimicrobials. To shed light on the complex array of molecular pathways involved in bacterial stress responses we challenged 32 diverse human pathogenic bacteria to 11 infection related stress conditions and catalogued their transcriptomes. more...
Organism:
Campylobacter jejuni; Francisella tularensis; Acinetobacter baumannii; Neisseria gonorrhoeae; Escherichia coli; Shigella flexneri; Aggregatibacter actinomycetemcomitans; Haemophilus influenzae; Staphylococcus aureus subsp. aureus MRSA252; Staphylococcus aureus subsp. aureus MSSA476; Helicobacter pylori; Enterococcus faecalis; Borreliella burgdorferi; Pseudomonas aeruginosa; Legionella pneumophila; Klebsiella pneumoniae; Yersinia pseudotuberculosis; Vibrio cholerae; Streptococcus suis; Streptococcus agalactiae; Streptococcus pneumoniae; Mycobacterium tuberculosis; Burkholderia pseudomallei; Neisseria meningitidis; Staphylococcus epidermidis; Streptococcus pyogenes; Listeria monocytogenes; Salmonella enterica; Achromobacter xylosoxidans
Type:
Expression profiling by high throughput sequencing
30 related Platforms
1122 Samples
Download data: TXT
Series
Accession:
GSE152295
ID:
200152295
14.

Differential expression of genes in Listeria monocytogenes under prolonged heat shock

(Submitter supplied) Microarray analysis was performed to identify the differentially expressed genes during heat stress by comparing the transcriptome of L. monocytogenes under optimal temperature (37°C), and prolonged heat shock (60°C for 9 minutes) conditions.
Organism:
Listeria monocytogenes
Type:
Expression profiling by array
Platform:
GPL4284
5 Samples
Download data: GPR
Series
Accession:
GSE26670
ID:
200026670
15.

Differential expression of genes in Listeria monocytogenes under thermo-tolerance condition of heat shock

(Submitter supplied) Previous studies have shown the increased thermo-tolerance of pathogenic bacteria if pre-exposed to temperatures above their optimal levels prior to a particular heat treatment. It was unclear, however, whether there was a direct relationship between the different gene expression and the induced thermo-tolerance. Microarray analysis was performed to identify the differentially expressed genes during heat stress by comparing the transcriptome of L. more...
Organism:
Listeria monocytogenes
Type:
Expression profiling by array
Platform:
GPL4284
5 Samples
Download data: GPR
Series
Accession:
GSE26570
ID:
200026570
16.

Chitin attenuates virulence gene expression of Listeria monocytogenes in vitro

(Submitter supplied) External signals are key for bacteria to sense their immediate environment and fine-tune gene expression accordingly. The foodborne pathogen Listeria monocytogenes senses a range of environmental cues in order to activate or deactivate the virulence-inducing transcriptional factor PrfA during transition between infectious and saprophytic lifecycles. Chitin is an abundant biopolymer formed from linked β-(1–4)-N-acetyl-D-glucosamine residues associated with fungi, the exoskeleton of insects and often incorporated into foods as a thickener or stabiliser. more...
Organism:
Listeria monocytogenes
Type:
Expression profiling by high throughput sequencing
Platform:
GPL26477
6 Samples
Download data: XLSX
Series
Accession:
GSE154844
ID:
200154844
17.

RNA-sequencing of L. monocytogenes under PrfA-inducing conditions refines the PrfA regulon and reveals a putative novel PrfA-dependent gene and its associated PrfA box

(Submitter supplied) Purpose: The objective of the present study was to refine the PrfA regulatory network using RNA-seq to characterize the L. monocytogenes transcriptome in a wt, ∆prfA, and prfA* under PrfA-inducing conditions. Methods: Sequence reads were aligned to the L. monocytogenes 10403S genome using the BWA-MEM algorithm, version 0.7.3a. The data for coverage per base on the sense and antisense strands were analyzed separately using SAMtools. more...
Organism:
Listeria monocytogenes
Type:
Expression profiling by high throughput sequencing
Platform:
GPL26477
9 Samples
Download data: TXT
Series
Accession:
GSE146507
ID:
200146507
18.

4-hydroxy-2-nonenal (4-HNE) induced transcriptional changes in Listeria monocytogenes

(Submitter supplied) Pathogens must counteract a wide array of antimicrobial responses, including the reactive oxygen species (ROS) burst. ROS mediated oxidation of host membrane poly-unsaturated fatty acids (PUFAs) leads to the production of the toxic alpha-beta carbonyl 4-hydroxy-2-nonenal (4-HNE). 4-HNE has been studied extensively in the context of sterile inflammation but understanding of its role during bacterial infection remains limited. more...
Organism:
Listeria monocytogenes 10403S
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20912
4 Samples
Download data: TXT
Series
Accession:
GSE150188
ID:
200150188
19.

Transcriptional analysis of the GlnR regulon of Listeria monocytogenes

(Submitter supplied) RNA-Seq analysis of L. monocytogenes wild-type and glnR null mutant strains was performed in a defined medium
Organism:
Listeria monocytogenes 10403S
Type:
Expression profiling by high throughput sequencing
Platform:
GPL28017
8 Samples
Download data: TSV
Series
Accession:
GSE143874
ID:
200143874
20.

Expression analysis of Listeria monocytogenes during adaptation in soil

(Submitter supplied) Investigation of whole genome gene expression level changes in Listeria monocytogenes EGD-e during incubation (0, 15 min, 30 min) in two types of soil extracts (TA, DA).
Organism:
Listeria monocytogenes EGD-e
Type:
Expression profiling by array
Platform:
GPL13478
15 Samples
Download data: PAIR
Series
Accession:
GSE29039
ID:
200029039
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