txid10090[orgn] AND "subtype Day4"[All Fields] - GEO DataSets - NCBI

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Select item 2000894051.

Early transcriptional and epigenetic regulation of CD8+ T cell differentiation revealed by single-cell RNA-seq

(Submitter supplied) During microbial infection, responding CD8+ T lymphocytes differentiate into heterogeneous subsets that together provide immediate and durable protection. To elucidate the dynamic transcriptional changes that underlie this process, we applied a single-cell RNA sequencing approach and analyzed individual CD8+ T lymphocytes sequentially throughout the course of a viral infection in vivo. Our analyses revealed a striking transcriptional divergence among cells that had undergone their first division and identified previously unknown molecular determinants controlling CD8+ T lymphocyte fate specification, including Ezh2, the catalytic component of the Polycomb Repressive Complex 2. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL17021 GPL21103
304 Samples

Download data: BED, CSV

Series

Accession:: GSE89405

ID:: 200089405

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 3023708732.

Organism:: Mus musculus

Source name:: CD8+ T cell

Platform:: GPL17021
Series:: GSE89405

Sample

Accession:: GSM2370873

ID:: 302370873

SRA Run Selector

Select item 3023708623.

Organism:: Mus musculus

Source name:: CD8+ T cell

Platform:: GPL17021
Series:: GSE89405

Sample

Accession:: GSM2370862

ID:: 302370862

SRA Run Selector

Select item 3023708294.

Organism:: Mus musculus

Source name:: CD8+ T cell

Platform:: GPL17021
Series:: GSE89405

Sample

Accession:: GSM2370829

ID:: 302370829

SRA Run Selector

Select item 3023708285.

Organism:: Mus musculus

Source name:: CD8+ T cell

Platform:: GPL17021
Series:: GSE89405

Sample

Accession:: GSM2370828

ID:: 302370828

SRA Run Selector

Select item 3023708276.

Organism:: Mus musculus

Source name:: CD8+ T cell

Platform:: GPL17021
Series:: GSE89405

Sample

Accession:: GSM2370827

ID:: 302370827

SRA Run Selector

Select item 3023708267.

Organism:: Mus musculus

Source name:: CD8+ T cell

Platform:: GPL17021
Series:: GSE89405

Sample

Accession:: GSM2370826

ID:: 302370826

SRA Run Selector

Select item 3023708258.

Organism:: Mus musculus

Source name:: CD8+ T cell

Platform:: GPL17021
Series:: GSE89405

Sample

Accession:: GSM2370825

ID:: 302370825

SRA Run Selector

Select item 3023708249.

Organism:: Mus musculus

Source name:: CD8+ T cell

Platform:: GPL17021
Series:: GSE89405

Sample

Accession:: GSM2370824

ID:: 302370824

SRA Run Selector

Select item 30237082310.

Organism:: Mus musculus

Source name:: CD8+ T cell

Platform:: GPL17021
Series:: GSE89405

Sample

Accession:: GSM2370823

ID:: 302370823

SRA Run Selector

Select item 30237082211.

Organism:: Mus musculus

Source name:: CD8+ T cell

Platform:: GPL17021
Series:: GSE89405

Sample

Accession:: GSM2370822

ID:: 302370822

SRA Run Selector

Select item 30237082112.

Organism:: Mus musculus

Source name:: CD8+ T cell

Platform:: GPL17021
Series:: GSE89405

Sample

Accession:: GSM2370821

ID:: 302370821

SRA Run Selector

Select item 30237082013.

Organism:: Mus musculus

Source name:: CD8+ T cell

Platform:: GPL17021
Series:: GSE89405

Sample

Accession:: GSM2370820

ID:: 302370820

SRA Run Selector

Select item 30237081914.

Organism:: Mus musculus

Source name:: CD8+ T cell

Platform:: GPL17021
Series:: GSE89405

Sample

Accession:: GSM2370819

ID:: 302370819

SRA Run Selector

Select item 30237081815.

Organism:: Mus musculus

Source name:: CD8+ T cell

Platform:: GPL17021
Series:: GSE89405

Sample

Accession:: GSM2370818

ID:: 302370818

SRA Run Selector

Select item 30237081716.

Organism:: Mus musculus

Source name:: CD8+ T cell

Platform:: GPL17021
Series:: GSE89405

Sample

Accession:: GSM2370817

ID:: 302370817

SRA Run Selector

Select item 30237081617.

Organism:: Mus musculus

Source name:: CD8+ T cell

Platform:: GPL17021
Series:: GSE89405

Sample

Accession:: GSM2370816

ID:: 302370816

SRA Run Selector

Select item 30237081518.

Organism:: Mus musculus

Source name:: CD8+ T cell

Platform:: GPL17021
Series:: GSE89405

Sample

Accession:: GSM2370815

ID:: 302370815

SRA Run Selector

Select item 30237081419.

Organism:: Mus musculus

Source name:: CD8+ T cell

Platform:: GPL17021
Series:: GSE89405

Sample

Accession:: GSM2370814

ID:: 302370814

SRA Run Selector

Select item 30237076220.

Organism:: Mus musculus

Source name:: CD8+ T cell

Platform:: GPL17021
Series:: GSE89405

Sample

Accession:: GSM2370762

ID:: 302370762

SRA Run Selector

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