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Items: 1 to 20 of 135

1.

LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways [LIS1_ESCs_totalRNAseq]

(Submitter supplied) We analyzed gene expression changes in mouse embryonic stem cells.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
8 Samples
Download data: TXT
Series
Accession:
GSE225581
ID:
200225581

PubMed Full text in PMC Similar studies

2.

LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways

(Submitter supplied) Lissencephaly-1 (LIS1) is associated with neurodevelopmental diseases and is known to regulate the molecular motor cytoplasmic dynein activity. Here we show that LIS1 is essential for the viability of mouse embryonic stem cells (mESCs), and it governs the physical properties of these cells. LIS1 dosage substantially affects gene expression, and we uncovered an unexpected interaction of LIS1 with RNA and RNA-binding proteins, most prominently the Argonaute complex. more...
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
4 related Platforms
166 Samples
Download data: BEDGRAPH, TXT
Series
Accession:
GSE198390
ID:
200198390

PubMed Full text in PMC Similar studies

3.

LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways [8_totalRNA_B]

(Submitter supplied) We analyzed gene expression changes in mouse embryonic stem cells.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21273
16 Samples
Download data: TXT
Series
Accession:
GSE198389
ID:
200198389

PubMed Full text in PMC Similar studies

4.

LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways [7_smRNA_B]

(Submitter supplied) We analyzed small RNA expression changes in embryonic stem cells.
Organism:
Mus musculus
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL21626
16 Samples
Download data: TXT
Series
Accession:
GSE198388
ID:
200198388

PubMed Full text in PMC Similar studies

5.

LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways [6_ATAC_seq]

(Submitter supplied) Genome binding/occupancy profiling by high throughput sequencing in mouse embryonic stem cells
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL21273 GPL21626
18 Samples
Download data: BEDGRAPH
Series
Accession:
GSE198387
ID:
200198387

PubMed Full text in PMC Similar studies

6.

LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways [5_smRNA_A]

(Submitter supplied) We analyzed small RNA expression changes in embryonic stem cells.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21626
20 Samples
Download data: TXT
Series
Accession:
GSE198350
ID:
200198350

PubMed Full text in PMC Similar studies

7.

LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways [4_totalRNA_A]

(Submitter supplied) We analyzed gene expression changes in mouse embryonic stem cells.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21626
20 Samples
Download data: TXT
Series
Accession:
GSE198349
ID:
200198349

PubMed Full text in PMC Similar studies

8.

LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways [3_seCLIP_seq]

(Submitter supplied) LIS1 dosage substantially affects gene expression, and we uncovered RNA binding properties in embryonic stem cells.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21626
4 Samples
Download data: BEDGRAPH
Series
Accession:
GSE198344
ID:
200198344

PubMed Full text in PMC Similar studies

9.

LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways [1_MARS_seq_A]

(Submitter supplied) We analyzed LIS1 dosage dependent gene expression changes in mouse and human embryonic stem cells.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21626
24 Samples
Download data: TXT
Series
Accession:
GSE198342
ID:
200198342

PubMed Full text in PMC Similar studies

10.

mESCs,TT-FHAgo2:LIS1-GFP-OE (+Dox), FBS+LIF condition, Rep#4 - totalRNA-seq

Organism:
Mus musculus
Source name:
mouse embryonic stem cells
Platform:
GPL21273
Series:
GSE198389 GSE198390
Download data: TXT
Sample
Accession:
GSM5946070
ID:
305946070

SRA Run Selector

11.

mESCs,TT-FHAgo2:LIS1-GFP-OE (+Dox), FBS+LIF condition, Rep#3 - totalRNA-seq

Organism:
Mus musculus
Source name:
mouse embryonic stem cells
Platform:
GPL21273
Series:
GSE198389 GSE198390
Download data: TXT
Sample
Accession:
GSM5946069
ID:
305946069

SRA Run Selector

12.

mESCs,TT-FHAgo2:LIS1-GFP-OE (+Dox), FBS+LIF condition, Rep#2 - totalRNA-seq

Organism:
Mus musculus
Source name:
mouse embryonic stem cells
Platform:
GPL21273
Series:
GSE198389 GSE198390
Download data: TXT
Sample
Accession:
GSM5946068
ID:
305946068

SRA Run Selector

13.

mESCs,TT-FHAgo2:LIS1-GFP-OE (+Dox), FBS+LIF condition, Rep#1 - totalRNA-seq

Organism:
Mus musculus
Source name:
mouse embryonic stem cells
Platform:
GPL21273
Series:
GSE198389 GSE198390
Download data: TXT
Sample
Accession:
GSM5946067
ID:
305946067

SRA Run Selector

14.

mESCs,TT-FHAgo2 (+Dox), FBS+LIF condition, Rep#4 - totalRNA-seq

Organism:
Mus musculus
Source name:
mouse embryonic stem cells
Platform:
GPL21273
Series:
GSE198389 GSE198390
Download data: TXT
Sample
Accession:
GSM5946066
ID:
305946066

SRA Run Selector

15.

mESCs,TT-FHAgo2 (+Dox), FBS+LIF condition, Rep#3 - totalRNA-seq

Organism:
Mus musculus
Source name:
mouse embryonic stem cells
Platform:
GPL21273
Series:
GSE198389 GSE198390
Download data: TXT
Sample
Accession:
GSM5946065
ID:
305946065

SRA Run Selector

16.

mESCs,TT-FHAgo2 (+Dox), FBS+LIF condition, Rep#2 - totalRNA-seq

Organism:
Mus musculus
Source name:
mouse embryonic stem cells
Platform:
GPL21273
Series:
GSE198389 GSE198390
Download data: TXT
Sample
Accession:
GSM5946064
ID:
305946064

SRA Run Selector

17.

mESCs,TT-FHAgo2 (+Dox), FBS+LIF condition, Rep#1 - totalRNA-seq

Organism:
Mus musculus
Source name:
mouse embryonic stem cells
Platform:
GPL21273
Series:
GSE198389 GSE198390
Download data: TXT
Sample
Accession:
GSM5946063
ID:
305946063

SRA Run Selector

18.

mESCs,TT-FHAgo2:LIS1-GFP-OE, FBS+LIF condition, Rep#4 - totalRNA-seq

Organism:
Mus musculus
Source name:
mouse embryonic stem cells
Platform:
GPL21273
Series:
GSE198389 GSE198390
Download data: TXT
Sample
Accession:
GSM5946062
ID:
305946062

SRA Run Selector

19.

mESCs,TT-FHAgo2:LIS1-GFP-OE, FBS+LIF condition, Rep#3 - totalRNA-seq

Organism:
Mus musculus
Source name:
mouse embryonic stem cells
Platform:
GPL21273
Series:
GSE198389 GSE198390
Download data: TXT
Sample
Accession:
GSM5946061
ID:
305946061

SRA Run Selector

20.

mESCs,TT-FHAgo2:LIS1-GFP-OE, FBS+LIF condition, Rep#2 - totalRNA-seq

Organism:
Mus musculus
Source name:
mouse embryonic stem cells
Platform:
GPL21273
Series:
GSE198389 GSE198390
Download data: TXT
Sample
Accession:
GSM5946060
ID:
305946060

SRA Run Selector

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