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Items: 10

1.

Striatal gene expression data from 22-month-old CHL2 mice and control mice.

(Submitter supplied) Achieving a mechanistic understanding of disease and initiating preclinical therapeutic trials necessitate the study of huntingtin toxicity and its remedy in model systems. To allow the engagement of appropriate experimental paradigms, Huntington’s disease (HD) models need to be validated in terms of how they recapitulate a particular aspect of human disease. In order to examine transcriptome-related effects of mutant huntingtin, we compared striatal mRNA profiles from seven genetic mouse models of disease to that of postmortem human HD caudate using microarray analysis. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
8 Samples
Download data: CEL
Series
Accession:
GSE10202
ID:
200010202
2.

Mutant huntingtin's effects on striatal gene expression in mice

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array
Platforms:
GPL1261 GPL81
32 Samples
Download data: CEL
Series
Accession:
GSE10263
ID:
200010263
3.

striatum_wt_22m_200

Organism:
Mus musculus
Source name:
Striatum (brain) wild-type, 22 months, 200
Platform:
GPL1261
Series:
GSE10202 GSE10263
Download data: CEL
Sample
Accession:
GSM257687
ID:
300257687
4.

striatum_wt_22m_180

Organism:
Mus musculus
Source name:
Striatum (brain) wild-type, 22 months, 180
Platform:
GPL1261
Series:
GSE10202 GSE10263
Download data: CEL
Sample
Accession:
GSM257686
ID:
300257686
5.

striatum_wt_22m_170

Organism:
Mus musculus
Source name:
Striatum (brain) wild-type, 22 months, 170
Platform:
GPL1261
Series:
GSE10202 GSE10263
Download data: CEL
Sample
Accession:
GSM257685
ID:
300257685
6.

striatum_wt_22m_161

Organism:
Mus musculus
Source name:
Striatum (brain) wild-type, 22 months, 161
Platform:
GPL1261
Series:
GSE10202 GSE10263
Download data: CEL
Sample
Accession:
GSM257684
ID:
300257684
7.

striatum_CHL2_22m_191

Organism:
Mus musculus
Source name:
Striatum (brain) CHL2 mutant, 22 months, 191
Platform:
GPL1261
Series:
GSE10202 GSE10263
Download data: CEL
Sample
Accession:
GSM257683
ID:
300257683
8.

striatum_CHL2_22m_154

Organism:
Mus musculus
Source name:
Striatum (brain) CHL2 mutant, 22 months, 154
Platform:
GPL1261
Series:
GSE10202 GSE10263
Download data: CEL
Sample
Accession:
GSM257682
ID:
300257682
9.

striatum_CHL2_22m_153

Organism:
Mus musculus
Source name:
Striatum (brain) CHL2 mutant, 22 months, 153
Platform:
GPL1261
Series:
GSE10202 GSE10263
Download data: CEL
Sample
Accession:
GSM257681
ID:
300257681
10.

striatum_CHL2_22m_141

Organism:
Mus musculus
Source name:
Striatum (brain) CHL2 mutant, 22 months, 141
Platform:
GPL1261
Series:
GSE10202 GSE10263
Download data: CEL
Sample
Accession:
GSM257680
ID:
300257680
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Supplemental Content

db=gds|term=txid10090[orgn]%20AND%20%22strain%20C57BL/6%20x%20CBA%20F1%20hybrid%22[All%20Fields]|query=1|qty=2|blobid=MCID_6636472f3ac0d96fcb71ca8a|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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