GEO DataSet Links for SRA (Select 9840379) - GEO DataSets

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Items: 2

Select item 3042582631.

Liver, GP2L

Organism:: Mus musculus

Source name:: Liver

Platform:: GPL24247
Series:: GSE143391

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Accession:: GSM4258263

ID:: 304258263

SRA Run Selector

Select item 2001433912.

Impact of Microbiome on Hepatic Drug Processing Genes in Mice during Pregnancy

(Submitter supplied) While microbiome and pregnancy are known to alter drug disposition, the interplay of the two physiological factors to impact expression and/or activity of drug processing genes (DPGs) has yet to be elucidated. This study aimed to investigate the effects of microbiome on host hepatic DPGs during pregnancy using conventional (CV) and germ-free (GF) mice. Four groups of female mice were used, namely CV non-pregnant (CVNP), GF non-pregnant (GFNP), CV pregnant (CVP), and GF pregnant (GFP) mice. more...