(Submitter supplied) Abstract: Cellular senescence, an integral component of aging and cancer, arises in response to diverse triggers, including telomere attrition, macromolecular damage, and signaling from activated oncogenes. At present, senescent cells are identified by the combined presence of multiple traits, such as senescence-associated protein expression and secretion, DNA damage, and β-galactosidase activity; unfortunately, these traits are neither exclusively nor universally present in senescent cells.
more...- Organism:
- Homo sapiens
- Type:
- Expression profiling by high throughput sequencing
- Platforms:
- GPL16791 GPL20301
- 37 Samples
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